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Adult patients undergoing pancreatectomy received clinician-rated facial flushing levels (0–2) while the Nix sensor recorded facial redness (a-value) at four points. Heart rate and arterial blood pressure were also tracked, comparing MTS versus non-MTS groups to identify threshold signals for future larger trials.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/objective-evaluation-of-facial-flushing-for-mesenteric-traction-syndrome-diagnosis-during-laparotomy-a-prospective-observational-pilot-study/468171/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/objective-evaluation-of-facial-flushing-for-mesenteric-traction-syndrome-diagnosis-during-laparotomy-a-prospective-observational-pilot-study/468171.png","ImageObject",300,407,{"name":92,"@type":93},"Asher","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the study objective regarding facial flushing in MTS patients?","Question",{"text":112,"@type":113},"To assess the concordance between objective facial flushing measured by a color sensor and subjective visual assessment, supporting the design of a future large-scale study with objective diagnostic tools.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were facial flushing and key physiologic signals measured?",{"text":117,"@type":113},"Anesthesiologists graded facial flushing visually on a 0–2 scale while the Nix color sensor measured facial redness (a-value) at four facial points; heart rate and arterial blood pressure were also recorded.",{"name":119,"@type":110,"acceptedAnswer":120},"What outcomes distinguished the MTS group from the non-MTS group?",{"text":121,"@type":113},"The MTS group showed significantly higher median change ratios in a-value and heart rate, along with a greater decrease in mean arterial pressure; subjective flushing levels also correlated with MTS diagnosis.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},468171,1791095131,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},687197207639,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Ikki et al. JA Clinical Reports (2026) 12:6 [https://doi.org/10.1186/s40981-025-00843-3](https://doi.org/10.1186/s40981-025-00843-3)  \nJA Clinical Reports  \nCLINICAL RESEARCH ARTICLE Open Access  \nObjective evaluation of facial flushing for mesenteric traction syndrome diagnosis during laparotomy: a prospective observational pilot study  \nYutaro Ikki 1, Takeshi Negita 1, Kimitoshi Nishiwaki2 and Takahiro Tamura2*  \nAbstract  \nBackground We aimed to evaluate the concordance between facial flushing assessment using an objective color sensor and subjective visual assessment in patients with mesenteric traction syndrome (MTS), to inform the design of a future large-scale study that incorporates objective diagnostic tools.  \nMethods In this prospective pilot study, we enrolled adult patients who underwent pancreatectomy. Anesthesiologists assessed the degree of facial flushing subjectively using a scale of levels 0–2 . Simultaneously, the Nix color sensor objectively measured the facial redness (a-value) at four facial points. Heart rate and arterial blood pressure were also recorded. Based on the anesthesiologist’s diagnosis, patients were categorized into either the MTS or non-MTS group. We compared the ratio of changes in a-value, heart rate, and blood pressure between the two groups, and their thresholds were also calculated.  \nResults We included 38 patients: 14 in the MTS group and 24 in the non-MTS group. The MTS group showed significantly higher median change ratio in a-value (0 .45 vs. 0. 25, P = 0 . 02) and heart rate (0 .45 vs. 0. 23, P \u003C 0. 01) and a greater decrease in mean arterial pressure (-0 . 26 vs. -0. 14, P = 0 . 01) than the non-MTS group. Subjective flushing levels correlated with MTS diagnosis (P \u003C 0. 01) . While the Nix sensor detected flushing in some subjectively undiagnosed cases, one patient in the non-MTS group met all three objective thresholds.  \nConclusion Objective evaluation of facial flushing using a color sensor is feasible and may enhance conventional assessment methods. To further improve the accuracy of objective evaluation, this pilot study may lead to a largerscale study including blood tests.  \nKeywords Mesenteric traction syndrome, Monitoring, Facial flushing  \n*Correspondence:  \nTakahiro Tamura  \n[tamura.takahiro.x5@f.mail.nagoya-u.ac.jp](tamura.takahiro.x5@f.mail.nagoya-u.ac.jp)  \n1Department of Anesthesiology, Chitahanto Medical Center, Handa, Japan  \n2Department of Anesthesiology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-Ku, Nagoya 466-8550, Japan  \n© The Author(s) 2026. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit [http://creativecommons.org/licenses/by/4.0/](http://creativecommons.org/licenses/by/4.0/.)[.](http://creativecommons.org/licenses/by/4.0/.)  \nIkki et al. JA Clinical Reports (2026) 12:6  \nBackground  \nMesenteric traction syndrome (MTS) is characterized by a clinical triad of hypotension, tachycardia, and facial flushing, typically triggered by surgical manipulation of the mesentery [1, 2]. MTS reportedly occurs in 30–85% of patients undergoing abdominal surgery [3–6] and is believed to result from prostacyclin (PGI2) release due tomesenteric traction [3].  \nHowever, the diagnosis of MTS currently re","cbCairm3F0co3JQZ","https://ap.wps.com/l/cbCairm3F0co3JQZ","pdf",1508338,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusion\n# Background\n## Rationale for objective facial flushing assessment\n## Current diagnostic limitations and need for standardization","[{\"question\":\"What was the study objective regarding facial flushing in MTS patients?\",\"answer\":\"To assess the concordance between objective facial flushing measured by a color sensor and subjective visual assessment, supporting the design of a future large-scale study with objective diagnostic tools.\"},{\"question\":\"How were facial flushing and key physiologic signals measured?\",\"answer\":\"Anesthesiologists graded facial flushing visually on a 0–2 scale while the Nix color sensor measured facial redness (a-value) at four facial points; heart rate and arterial blood pressure were also recorded.\"},{\"question\":\"What outcomes distinguished the MTS group from the non-MTS group?\",\"answer\":\"The MTS group showed significantly higher median change ratios in a-value and heart rate, along with a greater decrease in mean arterial pressure; subjective flushing levels also correlated with MTS diagnosis.\"}]","Objective evaluation of facial flushing for mesenteric traction syndrome diagnosis during laparotomy - a prospective observational pilot study | PDF",1790773846,23]