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Describes NIH funding governance through institutes and centers, interdisciplinary team-based approaches, and the activity flow covering budget allocation, scientific program development, and grantee research. Details major stages including strategic vision, congressional justification, appropriations, apportionment, allotment, and sub-allotment, followed by how funding opportunity announcements drive applicant preparation, submission timelines, and review leading to awards.",{"@graph":69,"@context":116},[70,84,99],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/nhgri-grant-funding-review-and-award-the-path-from-nhgri-appropriations-to-scientific-discovery/618909/",{"url":83,"name":65,"@type":85,"author":86,"headline":65,"publisher":89,"fileFormat":92,"inLanguage":63,"description":67,"dateModified":93,"datePublished":93,"encodingFormat":92,"isAccessibleForFree":94,"interactionStatistic":95},"DigitalDocument",{"name":87,"@type":88},"Miles","Person",{"url":74,"name":90,"@type":91},"DocShare","Organization","application/pdf","2026-10-20",true,{"@type":96,"interactionType":97,"userInteractionCount":4},"InteractionCounter",{"@type":98},"ViewAction",{"@type":100,"mainEntity":101},"FAQPage",[102,108,112],{"name":103,"@type":104,"acceptedAnswer":105},"How does NHGRI ensure the impact of its research dollars?","Question",{"text":106,"@type":107},"NHGRI uses innovative, team-based methods and assembles interdisciplinary research teams to ensure funded projects advance genomics research. Its stewardship relies on a rigorous application and review process.","Answer",{"name":109,"@type":104,"acceptedAnswer":110},"What are the main stages between NHGRI appropriations and funded research?",{"text":111,"@type":107},"The process follows strategic planning into budget allocation and scientific program development, then moves to grantee research. It includes appropriations, apportionment, allotment, and sub-allotment steps that transfer and divide funding authority.",{"name":113,"@type":104,"acceptedAnswer":114},"How do researchers participate in NHGRI funding opportunities?",{"text":115,"@type":107},"Researchers apply through funding opportunity announcements (FOAs), after preparing required registrations and meeting specific FOA requirements. The document outlines key dates such as open dates, application periods, letter of intent deadlines, and submission timing before review and award.","https://schema.org",{"og:url":83,"og:type":118,"og:title":65,"og:site_name":90,"og:description":67},"article",{"robots":120,"canonical":83},"index,follow",{"doc_id":122,"site_id":62},618909,1792461975,{"code":4,"msg":5,"data":125},{"doc_id":122,"user_id":126,"nickname":87,"user_avatar":127,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":128,"file_id":129,"file_url":130,"file_type":131,"file_size":132,"view_count":4,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":14,"language":133,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":134,"faqs":135,"seo_title":136,"seo_description":67,"update_tm":123,"read_time":24},13056703019404,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","NHGRI Grant Funding, Review and Award  \nThe Path from NHGRI Appropriations to Scientific Discovery    \nThe National Institutes of Health (NIH) is the largest public funder of biomedical research in the world. NIH provides funding through its 27 institutes and centers, each with unique research missions, priorities, budgets, and funding strategies. The National Human Genome Research Institute (NHGRI) builds on its leadership role in sequencing and understanding the human genome to advance genomics research at NIH and the scientific and medical community at-large.  \nAs one of the smaller institutes at NIH, NHGRI works to make every dollar we spend as impactful as possible by using innovative, team-based methods. We assemble interdisciplinary research teams made up of scientists, clinicians, ethicistsand other experts, and we ensure they have the funding and resources to advance genomics research. NHGRI funded $430 million in extramural research at 184 institutions in 2020. Stewardship of this investment involves a rigorous application and review process.  \nActivity Types  \nBudget Allocation  \nScientific Program Development  \nGrantee Research  \nActivity Information Timeframe  \nBudget Allocation Scientific Program Development  \n\n| Strategic Planning of NHGRI Research Priorities | NHGRI sets the big picture for the research projects it will fund through strategic planning. The 2020 NHGRI Strategic Vision (Nature 586 , 683–692) articulates a vision for genomics research at The Forefront of Genomics that outlines the most compelling opportunities for human genomics research, informed by a multi-year planning process that involved over 50 events nationally and internationally with a wide and diverse range of stakeholders. | Ongoing process |\n| --- | --- | --- |\n| Congressional\u003Cbr>Justification | The annual NHGRI Congressional Justification provides the Senate and House Appropriations Committees detailed estimates and justifications for research and research support activities (e.g. , infrastructure and administrative) . | - |\n| Appropriation of Funds | The federal appropriations process provides NHGRI with budget authority each fiscal year. |  |\n|  | Budget authority is given to carry out Section 301 and Title IV of the Public Health Service | Before Oct. 1 or |\n|  | Act with respect to human genome research. Authority provided by appropriations is not immediately available for obligation or expenditure. | Variable |\n| Apportionment by the Office of Management and Budget | The Office of Management and Budget (OMB) distributes funding available for obligation to | Before Nov. 1 or |\n|  | NIH. NIH must receive the funds from OMB no later than 30 days after the start of the new | ≤ 30 days after |\n|  | fiscal year or 30 days after enactment of the appropriations act. | appropriation |\n| Allotment by NIH\u003Cbr>Office of Budget | Allotment by the NIH Office of Budget (OB) transfers authority over the funds as allowances from the director of NIH to directors of institutes and centers, such as the NHGRI director, to incur obligations within a specified amount, within a specified period. | - |\n| Sub-Allotment by NHGRI Budget Office | The NHGRI Budget Office further divides these funds within the operating budget for the Institute, following NHGRI’s policies and priorities. First, NHGRI funds projects and centers that have commitments from previous years. NHGRI funds each grant for about 3 years, on average. The Institute uses the remainder of the funds on operations, new strategic scientific funding, small business grants, and ethical, legal and social implications (ELSI) research. | - |\n\nActivity  \nInformation  \nTimeframe  \nGrantee Research Budget Allocation Scientific Program Development  \n\n| Preparation of Funding Opportunity Announcements | For new strategic scientific funding, NHGRI solicits applications from researchers across the U.S. with projects aligned with the Institute’s mission and priorities. Grant support availability is typicall","cbCaioSJBJmOa7qG","https://ap.wps.com/l/cbCaioSJBJmOa7qG","pdf",174767,"English","# Activity Types\n## Budget Allocation\n## Scientific Program Development\n## Grantee Research\n# Funding and Review Process\n## Strategic Vision and Planning\n## Congressional Justification\n## Appropriations, Apportionment, and Allotment\n## Funding Opportunity Announcements (FOAs)\n## Application and Review Timeframes","[{\"question\":\"How does NHGRI ensure the impact of its research dollars?\",\"answer\":\"NHGRI uses innovative, team-based methods and assembles interdisciplinary research teams to ensure funded projects advance genomics research. Its stewardship relies on a rigorous application and review process.\"},{\"question\":\"What are the main stages between NHGRI appropriations and funded research?\",\"answer\":\"The process follows strategic planning into budget allocation and scientific program development, then moves to grantee research. It includes appropriations, apportionment, allotment, and sub-allotment steps that transfer and divide funding authority.\"},{\"question\":\"How do researchers participate in NHGRI funding opportunities?\",\"answer\":\"Researchers apply through funding opportunity announcements (FOAs), after preparing required registrations and meeting specific FOA requirements. The document outlines key dates such as open dates, application periods, letter of intent deadlines, and submission timing before review and award.\"}]","NHGRI Grant Funding, Review and Award - The Path from NHGRI Appropriations to Scientific Discovery | PDF"]