[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-331990-105":59,"doc-detail-331990-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","multiple-carcinomas-in-a-woman-with-hiv-infection-a-case-report-and-literature-review","Multiple carcinomas in a woman with HIV infection - a case report and literature review","","Non-acquired immunodeficiency syndrome-defining cancers (NADCs) are malignancies occurring in persons living with human immunodeficiency virus (PLWHIV) that are not primarily driven by host immunodeficiency. The work reports a 36-year-old woman with a 2-year history of an anal wound and right breast mass, subsequently diagnosed with breast and anal cancers. Chemotherapy and antiretroviral therapy were initiated but discontinued early with loss to follow-up. The review emphasizes early HIV identification, prompt cancer-care linkage, and screening for NADCs.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/multiple-carcinomas-in-a-woman-with-hiv-infection-a-case-report-and-literature-review/331990/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/multiple-carcinomas-in-a-woman-with-hiv-infection-a-case-report-and-literature-review/331990.png","ImageObject",300,407,{"name":92,"@type":93},"Olivia Brown","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What are non-acquired immunodeficiency syndrome-defining cancers (NADCs) in PLWHIV?","Question",{"text":112,"@type":113},"NADCs are malignancies that occur in persons living with HIV and are not primarily caused by the host’s immunodeficiency. They represent a growing source of morbidity in PLWHIV.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What clinical findings led to the diagnoses in the reported case?",{"text":117,"@type":113},"A 36-year-old woman presented with a 2-year history of an anal wound and a right breast mass. Clinical and laboratory evaluations identified both breast and anal cancers.",{"name":119,"@type":110,"acceptedAnswer":120},"How were treatment and follow-up handled in the case?",{"text":121,"@type":113},"Chemotherapy and antiretroviral therapy were started, but the patient discontinued treatment early and was lost to follow-up.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},331990,1790119893,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},16904993612988,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Multiple carcinomas in a woman with HIV infection:  \na case report and literature review  \nJohn Adi Ashindoitiang 1 ,  \nVictor Ikechukwu Carnice Nwagbara 1, Mba Okpan Ozinko 1 ,  \nTheophilus Ipeh Ugbem2 and Maurice Efana Asuquo 1  \nJournal of International Medical Research 2024, Vol. 52(4) 1–9! The Author(s) 2024 Article reuse guidelines:  \n[sagepub.com/journals-permissions](sagepub.com/journals-permissions)[ ](sagepub.com/journals-permissions)[DOI: 10.1177/03000605241245011](DOI: 10.1177/03000605241245011)[ ](DOI: 10.1177/03000605241245011)[journals.sagepub.com/home/imr](journals.sagepub.com/home/imr)  \nAbstract  \nNon-acquired immunodeficiency syndrome-defining cancers (NADCs) are malignancies in persons living with human immunodeficiency virus (PLWHIV) and are not primarily due to the host’s immunodeficiency. There is renewed clinical interest in long-term morbidities in PLWHIV as well as malignancies that occur in this population. We herein describe a 36-year-old woman with a 2-year history of an anal wound and right breast mass. She had been diagnosed with HIV infection prior to the development of these lesions. Clinical and laboratory evaluations led to diagnoses of breast and anal cancers. Chemotherapy and antiretroviral therapy were begun, but the patient discontinued these treatments early and was lost to follow-up. NADCs will continue to be a major clinical issue as the global population ages. This presentation of two NADCs (breast and anal cancers) in a PLWHIV further highlights the burden of multiple malignancies on the depleted health of HIV-infected patients. Early identification and treatment of HIV upon patients’ presentation to cancer care sites and screening for NADCs at HIV/AIDS care sites are recommended for improved outcomes.  \n1 Department of Surgery, University of Calabar/University of Calabar Teaching Hospital, Calabar, Nigeria 2Department of Pathology, University of Calabar/ University of Calabar Teaching Hospital, Calabar, Nigeria  \nCorresponding author:  \nJohn Adi Ashindoitiang, Department of Surgery, University of Calabar Teaching Hospital, UNICAL Hotel Road, Calabar, Cross River State 540281, Nigeria.  \nEmail: [ashindoitiang90@yahoo.com](ashindoitiang90@yahoo.com)  \nCreative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative  \nCommons Attribution-NonCommercial 4.0 License ([https://creativecommons.org/licenses/by-nc/4.0/](https://creativecommons.org/licenses/by-nc/4.0/)) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages ([https://us.sagepub.com/en-us/nam/open-access-at-sage](https://us.sagepub.com/en-us/nam/open-access-at-sage)).  \nKeywords  \nBreast cancer, anal cancer, non-acquired immunodeficiency syndrome-defining cancer, person living with human immunodeficiency virus, screening, case report  \nDate received: 24 October 2023; accepted: 15 March 2024  \nIntroduction  \nNon-acquired immunodeficiency syndromedefining cancers (NADCs) are malignancies in people living with human immunodeficiency virus (PLWHIV) and are not primarily due to the host’s immunodeficiency.1 NADCs are a growing cause of morbidity for PLWHIV.2 Highly active antiretroviral therapy (HAART) has transformed HIV infection from a fatal disease to a chronic condition.3,4 The association between HIV and malignancies became evident early in the HIV epidemic. Kaposi sarcoma (KS) was the first described AIDS-defining cancer (ADC); others include cervical cancer and non-Hodgkin lymphoma. 1,3 These three ADCs are due to HIV-induced T-cell reduction and consequent immunosuppression.1 Since the introduction of HAART, the incidence of NADCs has increased among PLWHIV in both developed and developing countries. This rise is projected to persist in future, whereas the incidence of ADCs has decreased.2,3 Thereis renewed clinical interest in long-term morbidities as w","cbCaipLAEaDTAh5x","https://ap.wps.com/l/cbCaipLAEaDTAh5x","pdf",686932,"English","# Abstract\n# Keywords\n# Introduction\n# Case report","[{\"question\":\"What are non-acquired immunodeficiency syndrome-defining cancers (NADCs) in PLWHIV?\",\"answer\":\"NADCs are malignancies that occur in persons living with HIV and are not primarily caused by the host’s immunodeficiency. They represent a growing source of morbidity in PLWHIV.\"},{\"question\":\"What clinical findings led to the diagnoses in the reported case?\",\"answer\":\"A 36-year-old woman presented with a 2-year history of an anal wound and a right breast mass. Clinical and laboratory evaluations identified both breast and anal cancers.\"},{\"question\":\"How were treatment and follow-up handled in the case?\",\"answer\":\"Chemotherapy and antiretroviral therapy were started, but the patient discontinued treatment early and was lost to follow-up.\"}]","Multiple carcinomas in a woman with HIV infection - a case report and literature review | PDF",1789996195,23]