[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-450043-105":59,"doc-detail-450043-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","motivational-significance-of-control-failures-as-a-window-on-risk-for-problematic-alcohol-involvement-commentary","Motivational Significance of Control Failures as a Window on Risk for Problematic Alcohol Involvement - Commentary","","Motivational Significance of Control Failures as a Window on Risk for Problematic Alcohol Involvement analyzes findings from a Biological Psychiatry: Global Open Science study (Boer et al.). Smaller error-related negativity (ERN) amplitude is linked to multiple AUD risk behaviors, while larger error positivity (Pe) also relates to binge drinking frequency. The commentary highlights the cohort study’s value and confounding control, then questions whether cognitive control frameworks best explain electrophysiological markers without accompanying behavioral measures, proposing affective-motivational dysregulation as an alternative account.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/motivational-significance-of-control-failures-as-a-window-on-risk-for-problematic-alcohol-involvement-commentary/450043/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/motivational-significance-of-control-failures-as-a-window-on-risk-for-problematic-alcohol-involvement-commentary/450043.png","ImageObject",300,407,{"name":92,"@type":93},"Patrick","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What associations did Boer et al. report between error signals and AUD risk behaviors?","Question",{"text":112,"@type":113},"Smaller ERN amplitude was associated with several AUD risk behaviors, including earlier initiation of alcohol use and more frequent binge drinking. Unexpectedly, larger Pe values were also associated with higher binge drinking frequency.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Why does the commentary question the cognitive control interpretation of the electrophysiological findings?",{"text":117,"@type":113},"It argues there is little evidence that ERN (and related measures) directly indexes between-person differences in cognitive control, and it notes a conceptual inconsistency in treating neurophysiological responses to control failures as control itself.",{"name":119,"@type":110,"acceptedAnswer":120},"What alternative explanation does the commentary propose for the observed relationships?",{"text":121,"@type":113},"The commentary contends the findings may reflect underlying trait dimensions tied to affective-motivational dysregulation that covary with substance involvement, rather than aberrant cognitive control per se.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},450043,1791096387,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":14,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":24,"preview_page_count":4},549758146520,"https://ap-avatar.wpscdn.com/avatar/80002397d8c0411e94?_k=1775819394049821470","Commentary  \nBiological Psychiatry: GOS  \nMotivational Significance of Control Failures as a Window on Risk for Problematic Alcohol Involvement  \nBruce D. Bartholow  \nIn a recent study published in Biological Psychiatry: Global Open Science, Boer et al. (1) present data from the largest study to date examining associations between electrophysiological responses to performance errors and risk for alcohol use disorder (AUD) in young people. They reported that smaller error-related negativity (ERN) amplitude was associated with several AUD risk behaviors, including earlier initiation of alcohol use and higher frequency of binge drinking. Unexpectedly, larger error positivity (Pe) values were also associated with higher binge drinking frequency. The authors interpreted their findings as consistent with the notion that altered cognitive control increases risk for early and potentially problematic alcohol use in adolescence.  \nThe study of Boer et al. (1) represents an important contribution to the literature on neurocognitive AUD risk factors in adolescents and emerging adults. The large birth cohort sample allowed the researchers to account for numerous person-level confounders (e.g. , IQ, prenatal alcohol/tobacco exposure) that otherwise could offer alternative explanations for associations that they observed. The study also adds large-scale validation of previously identified links between blunted ERN amplitude and alcohol/drug involvement. However, several conceptual and methodological issues in the work of Boer etal. (1) warrant some caution when considering their findings.  \nHow Should Individual Differences in Error Reactivity Be Interpreted?  \nBoer et al. (1) framed their findings in terms of aberrant cognitive control as an AUD risk factor. This framing makes sense in the context of the large literature linking control deficits with risky alcohol involvement, as well as the literature associating the ERN with cognitive control. However, there are reasons to question whether a cognitive control framework provides the best understanding of the findings of Boer et al.  \n(1) . First, as others have highlighted (2), there is little evidence linking ERN amplitude (or Pe or frontal midline theta power) with between-person differences in cognitive control. Rather, the ERN often is larger within persons in situations requiring greater control compared to situations in which control is deemphasized, and it should not be assumed that phenomena varying within individuals translate directly to betweenindividual differences.  \nSecond, there is a logical inconsistency in the idea that neurophysiological activity elicited by failures of control (i.e. , errors) is somehow indicative of control itself. To the extent that they relate to control at all, it seems more likely that  \nERN, Pe, and frontal midline theta power reflect functions adjacent and potentially antecedent to control adjustments. Considerable evidence links ERN amplitude with a cascade of affective/motivational processes that covary with the importance or significance of the error (3) . Given the known neural source of the ERN in the medial frontal cortex (especially dorsal anterior cingulate cortex), this signal likely reflects engagement of the salience network that functions to switch between default mode processing and the focused attention and motor control instigated by engagement of the frontoparietal executive control network (4) . Pe amplitude seems to index a distinct function that tracks the degree of postdecision evidence accumulation concerning the correctness of the decision/response, with larger amplitude indicating stronger evidence for an error (5) . Together, the ERN and Pe reflect processes integral to performance monitoring that, while clearly important for initiating control adjustments, should not be considered core elements of control.  \nA second reason why the findings of Boer et al. (1) may not best be interpreted through the lens of cognitive contro","cbCaiuLvi7M1hVUC","https://ap.wps.com/l/cbCaiuLvi7M1hVUC","pdf",140275,"English","# Motivational Significance of Control Failures as a Window on Risk for Problematic Alcohol Involvement\n## How Should Individual Differences in Error Reactivity Be Interpreted?","[{\"question\":\"What associations did Boer et al. report between error signals and AUD risk behaviors?\",\"answer\":\"Smaller ERN amplitude was associated with several AUD risk behaviors, including earlier initiation of alcohol use and more frequent binge drinking. Unexpectedly, larger Pe values were also associated with higher binge drinking frequency.\"},{\"question\":\"Why does the commentary question the cognitive control interpretation of the electrophysiological findings?\",\"answer\":\"It argues there is little evidence that ERN (and related measures) directly indexes between-person differences in cognitive control, and it notes a conceptual inconsistency in treating neurophysiological responses to control failures as control itself.\"},{\"question\":\"What alternative explanation does the commentary propose for the observed relationships?\",\"answer\":\"The commentary contends the findings may reflect underlying trait dimensions tied to affective-motivational dysregulation that covary with substance involvement, rather than aberrant cognitive control per se.\"}]","Motivational Significance of Control Failures as a Window on Risk for Problematic Alcohol Involvement - Commentary | PDF",1790731899]