[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-208059-en":3,"doc-seo-208059-105":30,"detail-sidebar-cat-0-en-105":90},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":4,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":14,"update_tm":28,"read_time":29},208059,687197207919,"Theodora","https://ap-avatar.wpscdn.com/avatar/a000253d6f5f7c60be?x-image-process=image/resize,m_fixed,w_180,h_180&k=1779446848396160552",4,"Exam","Monoclonal Antibodies - QP - Science Exam Questions","Science exam questions focusing on how monoclonal antibodies are used to detect anabolic steroids in urine and how vaccines relate to preventing HIV infection. The document includes tasks on anaerobic respiration during vigorous exercise, investigating exercise effects on heart rate, and explaining steroid use and regulation. It also tests understanding of hybridoma cell creation, antibody specificity, control areas in test strips, interpreting urine test results, and analyzing HIV spread, trends in diagnosed cases, and ratio calculations.","Questions are for separate science science students only  \nQ1 .  \nThis question is about exercise.  \n(a) During vigorous exercise, anaerobic respiration occurs in a person’s body.  \nExplain two effects of anaerobic respiration on the person’s body.  \n1  \n_________________________________________________________  \n___________________________________________________________  \n___________________________________________________________  \n2    \n\n|  |\n| --- |\n|  |\n\n(4)  \n(b) Design an investigation to show the effect of different types of exercise on the heart rate of athletes.  \n\n|  |\n| --- |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n\nAnabolic steroids are drugs.  \nAnabolic steroids:  \n• increase muscle mass in humans  \n• are banned in most competitive sports.  \nSome athletes take anabolic steroids to improve their performance in sport.  \n(c) Explain how taking anabolic steroids could improve an athlete’s performance.  \n\n|  |\n| --- |\n|  |\n|  |\n\n(2)  \nScientists use monoclonal antibodies to test for the presence of anabolic steroids in an athlete’s urine.  \nTo produce monoclonal antibodies, a mouse lymphocyte is combined with a tumour cell.  \n(d) What type of cell is created when a mouse lymphocyte and a tumour cell combine? (biology only) (HT only)  \nTick (✓) one box.  \nEmbryo  \nHybridoma  \nPhagocyte  \nStem cell  \n(1)  \n(e) Describe how scientists make monoclonal antibodies using the cell created when a mouse lymphocyte and a tumour cell combine. (biology only) (HT only)  \n\n|  |\n| --- |\n|  |\n|  |\n|  |\n|  |\n\n(3)  \n(f) What property makes a monoclonal antibody useful in detecting the presence of an anabolic steroid in urine? (biology only) (HT only)  \nTick (✓) one box.  \nA monoclonal antibody is quick and easy to produce.  \nA monoclonal antibody is specific to only one person’s urine.  \nA monoclonal antibody only binds to the anabolic steroid.  \nA monoclonal antibody can identify many different drugs at  \nthe same time.  \n(1)  \nFigure 1 shows a test strip that can detect the presence of an anabolic steroid inan athlete’s urine.  \nFigure 1  \nThe end of the test strip is dipped in urine.  \nThe urine moves up through the test strip.  \nThe test area and the control area contain a dye.  \nThe dye turns blue when monoclonal antibodies bind to it.  \n(g) Suggest the purpose of the control area in the test strip. (biology only)  \n(HT only)  \n___________________________________________________________  \n___________________________________________________________  \n(1)  \nFigure 2 shows the urine test results of four athletes.  \nFigure 2  \n(h) Describe the evidence in Figure 2 that shows the test for athlete B has not worked.  \nSuggest one reason why the test did not work. (biology only) (HT only)  \nEvidence    \nReason    \n(2)  \n(i) Which athlete has tested positive for anabolic steroids in their urine?  \n(biology only) (HT only)  \nTick (✓) one box.  \nA B C D  \n(1)  \n(Total 21 marks)  \nQ2 .  \nHuman immunodeficiency virus (HIV) is a pathogen.  \n(a) Give one way HIV can spread from one person to another person.  \n___________________________________________________________  \n___________________________________________________________  \n(1)  \nThe table below shows information about new cases of HIV diagnosed in the UK.  \n\n| Year | Number of new HIV cases in women | Number of new HIV cases in men |\n| --- | --- | --- |\n| 2010 | 376 | 2266 |\n| 2012 | 361 | 2310 |\n| 2014 | 397 | 2370 |\n| 2016 | 298 | 1886 |\n| 2018 | 242 | 1288 |\n\n(b) Describe the trends shown in the table above between 2010 and 2018.  \n\n|  |\n| --- |\n|  |\n|  |\n\n(2)  \n(c) Suggest one reason for the change in the number of new HIV cases between 2014 and 2018.  \n___________________________________________________________  \n___________________________________________________________  \n(1)  \n(d) Calculate the ratio of new cases of HIV in women to new cases of HIV in men in 2018.  \nGive your answer to 3 significant figures.  \n\n|  |\n| --- |\n|  |\n|  |\n|  |\n\nRatio (3 significant figures) ","cbCaileygnvxnHbN","https://ap.wps.com/l/cbCaileygnvxnHbN","pdf",1098894,1,8,"English","en",105,"# Q1 - Exercise, anabolic steroids detection using monoclonal antibodies\n## (a)-(i)\n# Q2 - HIV spread, UK case data trends, vaccination and monoclonal antibodies","[{\"question\":\"How does anaerobic respiration affect the body during vigorous exercise?\",\"answer\":\"The question requires explaining two effects of anaerobic respiration on the person’s body during vigorous exercise.\"},{\"question\":\"How are monoclonal antibodies produced using a mouse lymphocyte and a tumour cell?\",\"answer\":\"The questions state a mouse lymphocyte is combined with a tumour cell to create a specific cell, then monoclonal antibodies are made using that cell.\"},{\"question\":\"What evidence shows the test for athlete B has not worked, and give one reason?\",\"answer\":\"The document asks for the specific evidence from Figure 2 indicating athlete B’s test failure, plus one suggested reason why the test did not work.\"}]","Monoclonal Antibodies - QP - Science Exam Questions | PDF",1788602299,20,{"code":4,"msg":31,"data":32},"ok",{"site_id":24,"language":23,"slug":33,"title":13,"keywords":34,"description":14,"schema_data":35,"social_meta":85,"head_meta":87,"extra_data":89,"updated_unix":28},"monoclonal-antibodies-qp-science-exam-questions","",{"@graph":36,"@context":84},[37,53,67],{"@type":38,"itemListElement":39},"BreadcrumbList",[40,44,48,51],{"item":41,"name":42,"@type":43,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":45,"name":46,"@type":43,"position":47},"https://docshare.wps.com/document/","Document",2,{"item":49,"name":12,"@type":43,"position":50},"https://docshare.wps.com/document/exam/",3,{"item":52,"name":13,"@type":43,"position":11},"https://docshare.wps.com/document/monoclonal-antibodies-qp-science-exam-questions/208059/",{"url":52,"name":13,"@type":54,"author":55,"headline":13,"publisher":57,"fileFormat":60,"inLanguage":23,"description":14,"dateModified":61,"datePublished":61,"encodingFormat":60,"isAccessibleForFree":62,"interactionStatistic":63},"DigitalDocument",{"name":9,"@type":56},"Person",{"url":41,"name":58,"@type":59},"DocShare","Organization","application/pdf","2026-09-05",true,{"@type":64,"interactionType":65,"userInteractionCount":4},"InteractionCounter",{"@type":66},"ViewAction",{"@type":68,"mainEntity":69},"FAQPage",[70,76,80],{"name":71,"@type":72,"acceptedAnswer":73},"How does anaerobic respiration affect the body during vigorous exercise?","Question",{"text":74,"@type":75},"The question requires explaining two effects of anaerobic respiration on the person’s body during vigorous exercise.","Answer",{"name":77,"@type":72,"acceptedAnswer":78},"How are monoclonal antibodies produced using a mouse lymphocyte and a tumour cell?",{"text":79,"@type":75},"The questions state a mouse lymphocyte is combined with a tumour cell to create a specific cell, then monoclonal antibodies are made using that cell.",{"name":81,"@type":72,"acceptedAnswer":82},"What evidence shows the test for athlete B has not worked, and give one reason?",{"text":83,"@type":75},"The document asks for the specific evidence from Figure 2 indicating athlete B’s test failure, plus one suggested reason why the test did not work.","https://schema.org",{"og:url":52,"og:type":86,"og:title":13,"og:site_name":58,"og:description":14},"article",{"robots":88,"canonical":52},"index,follow",{"doc_id":7,"site_id":24},{"code":4,"msg":5,"data":91},[92,96,100,103,108,113,118,122,126,129,133],{"id":20,"doc_module":4,"doc_module_name":46,"category_name":93,"show_sort_weight":94,"slug":95},"Story & Novel",90,"story-novel",{"id":47,"doc_module":4,"doc_module_name":46,"category_name":97,"show_sort_weight":98,"slug":99},"Literature",80,"literature",{"id":11,"doc_module":4,"doc_module_name":46,"category_name":12,"show_sort_weight":101,"slug":102},70,"exam",{"id":104,"doc_module":4,"doc_module_name":46,"category_name":105,"show_sort_weight":106,"slug":107},5,"Comic",60,"comic",{"id":109,"doc_module":4,"doc_module_name":46,"category_name":110,"show_sort_weight":111,"slug":112},6,"Technology",50,"technology",{"id":114,"doc_module":4,"doc_module_name":46,"category_name":115,"show_sort_weight":116,"slug":117},7,"Healthcare",40,"healthcare",{"id":21,"doc_module":4,"doc_module_name":46,"category_name":119,"show_sort_weight":120,"slug":121},"Research & Report",30,"research-report",{"id":123,"doc_module":4,"doc_module_name":46,"category_name":124,"show_sort_weight":29,"slug":125},9,"Religion & Spirituality","religion-spirituality",{"id":29,"doc_module":4,"doc_module_name":46,"category_name":127,"show_sort_weight":29,"slug":128},"World Cup","world-cup",{"id":130,"doc_module":4,"doc_module_name":46,"category_name":131,"show_sort_weight":130,"slug":132},10,"Lifestyle","lifestyle",{"id":134,"doc_module":4,"doc_module_name":46,"category_name":135,"show_sort_weight":104,"slug":136},19,"General","general"]