[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-208060-en":3,"doc-seo-208060-105":30,"detail-sidebar-cat-0-en-105":91},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":14,"update_tm":28,"read_time":29},208060,1099514068365,"Aurelia","https://ap-avatar.wpscdn.com/avatar/10000253d8d9f28188e?_k=1776742907772140068",4,"Exam","Monoclonal Antibodies QP - RSV & Pregnancy Test Questions","Assessment questions on monoclonal antibodies in biology and health contexts. Students cover how to reduce RSV transmission, the steps to produce monoclonal antibodies using mice, and why placebo groups are used in a clinical trial, including calculation and evaluation of hospital admission data. Additional questions address pregnancy testing using HCG and antibody-based test strips, interpreting positive/negative results and explaining the mechanism. Further items relate monoclonal antibody test kits for detecting PVY in potatoes.","1.  \nA virus called RSV causes severe respiratory disease.  \n(a) Suggest two precautions that a person with RSV could take to reduce the  \nspread of the virus to other people.  \n1    \n2    \n___________________________________________________________________ (2)  \n(b) One treatment for RSV uses monoclonal antibodies which can be injected into the patient.  \nScientists can produce monoclonal antibodies using mice.  \nThe first step is to inject the virus into a mouse.  \nDescribe the remaining steps in the procedure to produce monoclonal antibodies.  \n\n|  |\n| --- |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n\n(3)  \n(c) Describe how injecting a monoclonal antibody for RSV helps to treat a patient suffering with the disease.  \n\n|  |\n| --- |\n|  |\n|  |\n\n(2)  \nA trial was carried out to assess the effectiveness of using monoclonal antibodies to treat patients with RSV.  \nSome patients were given a placebo.  \n[www.accesstuition.com](www.accesstuition.com)  \nPage 1  \nof 7  \n(d) Why were some patients given a placebo?  \n______________________________________________________________  \n_______________________________________________________________  \n(1)  \nA number of patients had to be admitted to hospital as they became so ill with RSV.  \nThe results are shown in the table below.  \n\n| Treatment received by patient | % of patients within each group admitted to hospital with RSV |\n| --- | --- |\n| Group A: Monoclonal antibody for RSV | 4.8 |\n| Group B: Placebo | 10.4 |\n\nThe trial involved 1 500 patients.  \n• Half of the patients (group A) were given the monoclonal antibodies.  \n• Half of the patients (group B) were given the placebo.  \n(e) Calculate the total number of patients admitted to hospital with RSV during the trial.  \n\n|  |\n| --- |\n|  |\n|  |\n\nTotal number of patients admitted to hospital =    \n(2)  \n(f) Evaluate how well the data in the table above supports the conclusion:  \n‘monoclonal antibodies are more effective at treating RSV than a placebo’.  \n\n|  |\n| --- |\n|  |\n|  |\n\n(2)(Total 12 marks)  \n[www.accesstuition.com](www.accesstuition.com)  \nPage 2 of 7  \n2.  \nMonoclonal antibodies are used to measure the levels of hormones in the blood. Pregnant women produce the hormone HCG.  \nHCG is excreted in urine.  \nFigure 1 shows four pregnancy test strips.  \nFigure 1  \n(a) Which test strip shows a negative test result?  \nTick one box.  \nA  B  C  D   \n(1)  \n(b) Monoclonal antibodies are used for pregnancy testing. Give one other use of monoclonal antibodies.  \n(1)  \n[www.accesstuition.com](www.accesstuition.com)  \nPage 3 of 7  \n(c) Figure 2 shows the parts of a pregnancy test strip. Figure 2  \nThe pregnancy test strip will show a positive test result when a woman is pregnant. Explain how the pregnancy test strip works to show a positive result.  \n\n|  |\n| --- |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n\n(6)(Total 8 marks)  \n[www.accesstuition.com](www.accesstuition.com)  \nPage 4 of 7  \n3.  \nPlants can be infected by fungi, viruses and insects. Aphids are small insects that carry pathogens.  \nThe diagram below shows an aphid feeding from a plant stem.  \n(a) An aphid feeds by inserting its sharp mouthpiece into the stem of a plant.  \nGive the reason why the mouthpiece of an aphid contains a high concentration of dissolved sugars after feeding.  \n___________________________________________________________________  \n___________________________________________________________________  \n(1)  \n[www.accesstuition.com](www.accesstuition.com)  \nPage 5 of 7  \n(b) Plants infected with aphids may show symptoms of magnesium deficiency. Magnesium deficiency symptoms include:  \n• yellow leaves  \n• stunted growth.  \nExplain how a deficiency of magnesium could cause these symptoms.  \n|  |\n| --- |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n|  |\n\n(5)  \n[www.accesstuition.com](www.accesstuition.com)  \nPage 6 of 7  \n(c) A farmer thinks a potato crop is infected with potato virus Y (PVY) .  \nThe farmer obtains a monoclonal antibody test kit for PVY.  \nTo make the monoclonal a","cbCaimOdGjDEkZQH","https://ap.wps.com/l/cbCaimOdGjDEkZQH","pdf",3187878,1,8,"English","en",105,"# Monoclonal antibodies and RSV\n## Precautions to reduce transmission\n## Producing monoclonal antibodies in mice\n## How monoclonal injections treat RSV\n## Clinical trial design: placebo\n## Calculations and evaluation of outcomes\n# Pregnancy testing with monoclonal antibodies\n## Negative vs positive test strips\n## Other applications of monoclonal antibodies\n## Mechanism of a positive result\n# Detecting viruses in plants and aphid impacts\n## Aphid feeding and sugar composition\n## Magnesium deficiency symptoms\n## Producing PVY monoclonal antibodies from isolated protein","[{\"question\":\"How can a person with RSV reduce the spread of the virus to others?\",\"answer\":\"The questions ask for two practical precautions that limit transmission from an RSV-infected person to others.\"},{\"question\":\"Why were some patients given a placebo in the RSV monoclonal antibody trial?\",\"answer\":\"A placebo group helps provide a comparison so that any improvement can be attributed to monoclonal antibodies rather than other factors or natural recovery.\"},{\"question\":\"How does a pregnancy test strip show a positive result using monoclonal antibodies?\",\"answer\":\"The test strip uses monoclonal antibodies that bind specifically to HCG; when HCG is present in a pregnant woman’s urine, the binding produces a visible positive result on the strip.\"}]","Monoclonal Antibodies QP - RSV & Pregnancy Test Questions | PDF",1788602301,20,{"code":4,"msg":31,"data":32},"ok",{"site_id":24,"language":23,"slug":33,"title":13,"keywords":34,"description":14,"schema_data":35,"social_meta":86,"head_meta":88,"extra_data":90,"updated_unix":28},"monoclonal-antibodies-qp-rsv-pregnancy-test-questions","",{"@graph":36,"@context":85},[37,53,68],{"@type":38,"itemListElement":39},"BreadcrumbList",[40,44,48,51],{"item":41,"name":42,"@type":43,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":45,"name":46,"@type":43,"position":47},"https://docshare.wps.com/document/","Document",2,{"item":49,"name":12,"@type":43,"position":50},"https://docshare.wps.com/document/exam/",3,{"item":52,"name":13,"@type":43,"position":11},"https://docshare.wps.com/document/monoclonal-antibodies-qp-rsv-pregnancy-test-questions/208060/",{"url":52,"name":13,"@type":54,"author":55,"headline":13,"publisher":57,"fileFormat":60,"inLanguage":23,"description":14,"dateModified":61,"datePublished":62,"encodingFormat":60,"isAccessibleForFree":63,"interactionStatistic":64},"DigitalDocument",{"name":9,"@type":56},"Person",{"url":41,"name":58,"@type":59},"DocShare","Organization","application/pdf","2026-09-06","2026-09-05",true,{"@type":65,"interactionType":66,"userInteractionCount":20},"InteractionCounter",{"@type":67},"ViewAction",{"@type":69,"mainEntity":70},"FAQPage",[71,77,81],{"name":72,"@type":73,"acceptedAnswer":74},"How can a person with RSV reduce the spread of the virus to others?","Question",{"text":75,"@type":76},"The questions ask for two practical precautions that limit transmission from an RSV-infected person to others.","Answer",{"name":78,"@type":73,"acceptedAnswer":79},"Why were some patients given a placebo in the RSV monoclonal antibody trial?",{"text":80,"@type":76},"A placebo group helps provide a comparison so that any improvement can be attributed to monoclonal antibodies rather than other factors or natural recovery.",{"name":82,"@type":73,"acceptedAnswer":83},"How does a pregnancy test strip show a positive result using monoclonal antibodies?",{"text":84,"@type":76},"The test strip uses monoclonal antibodies that bind specifically to HCG; 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