[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-27606-en":3,"doc-seo-27606-105":27,"detail-sidebar-cat-0-en-105":69},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":4,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":20,"language":21,"language_code":22,"site_id":23,"html_lang":22,"table_of_contents":15,"faqs":15,"seo_title":24,"seo_description":14,"update_tm":25,"read_time":26},27606,549758146520,"Patrick","https://ap-avatar.wpscdn.com/avatar/80002397d8c0411e94?_k=1775819394049821470",7,"Healthcare","Mineralocorticoids","This document provides comprehensive information on mineralocorticoids, focusing on their mechanism of action, indications, adverse reactions, and interactions. Mineralocorticoids, including aldosterone and desoxycorticosterone, are crucial in regulating sodium and water balance by promoting sodium conservation and potassium excretion. Aldosterone is identified as the more potent hormone. Deficiencies lead to sodium and water loss, alongside potassium retention. The document details contraindications for fludrocortisone, specifically in patients with hypersensitivity or systemic fungal infections. It strongly advises patients to adhere strictly to prescribed dosages, avoid abrupt discontinuation, and report any adverse reactions such as edema, muscle weakness, weight gain, anorexia, extremity swelling, dizziness, severe headache, or shortness of breath to their healthcare provider. Potential adverse effects from excessive or prolonged use, or rapid withdrawal, include edema, hypertension, cardiac enlargement (HF), increased sweating, allergic skin rash, and hypokalemia. Drug interactions are also highlighted, noting that fludrocortisone can decrease the efficacy of hydantoins and rifampin, and reduce serum salicylate levels. The information presented is intended for healthcare professionals and patients seeking detailed knowledge about mineralocorticoid therapy.","","cbCaicT7C3KfhM3e","https://ap.wps.com/l/cbCaicT7C3KfhM3e","pdf",580461,1,"English","en",105,"Mineralocorticoids | PDF",1778275704,3,{"code":4,"msg":28,"data":29},"ok",{"site_id":23,"language":22,"slug":30,"title":13,"keywords":15,"description":14,"schema_data":31,"social_meta":64,"head_meta":66,"extra_data":68,"updated_unix":25},"mineralocorticoids",{"@graph":32,"@context":63},[33,49],{"@type":34,"itemListElement":35},"BreadcrumbList",[36,40,44,46],{"item":37,"name":38,"@type":39,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":41,"name":42,"@type":39,"position":43},"https://docshare.wps.com/document/","Document",2,{"item":45,"name":12,"@type":39,"position":26},"https://docshare.wps.com/document/healthcare/",{"item":47,"name":13,"@type":39,"position":48},"https://docshare.wps.com/document/mineralocorticoids/27606",4,{"url":47,"name":13,"@type":50,"author":51,"headline":13,"publisher":53,"fileFormat":56,"description":14,"dateModified":57,"datePublished":57,"encodingFormat":56,"isAccessibleForFree":58,"interactionStatistic":59},"DigitalDocument",{"name":9,"@type":52},"Person",{"url":37,"name":54,"@type":55},"DocShare","Organization","application/pdf","2026-05-08",true,{"@type":60,"interactionType":61,"userInteractionCount":4},"InteractionCounter",{"@type":62},"ViewAction","https://schema.org",{"og:url":47,"og:type":65,"og:title":13,"og:site_name":54,"og:description":14},"article",{"robots":67,"canonical":47},"index,follow",{"doc_id":7,"site_id":23},{"code":4,"msg":5,"data":70},[71,75,79,83,88,93,96,101,106,109,113],{"id":20,"doc_module":4,"doc_module_name":42,"category_name":72,"show_sort_weight":73,"slug":74},"Story & Novel",90,"story-novel",{"id":43,"doc_module":4,"doc_module_name":42,"category_name":76,"show_sort_weight":77,"slug":78},"Literature",80,"literature",{"id":48,"doc_module":4,"doc_module_name":42,"category_name":80,"show_sort_weight":81,"slug":82},"Exam",70,"exam",{"id":84,"doc_module":4,"doc_module_name":42,"category_name":85,"show_sort_weight":86,"slug":87},5,"Comic",60,"comic",{"id":89,"doc_module":4,"doc_module_name":42,"category_name":90,"show_sort_weight":91,"slug":92},6,"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":42,"category_name":12,"show_sort_weight":94,"slug":95},40,"healthcare",{"id":97,"doc_module":4,"doc_module_name":42,"category_name":98,"show_sort_weight":99,"slug":100},8,"Research & Report",30,"research-report",{"id":102,"doc_module":4,"doc_module_name":42,"category_name":103,"show_sort_weight":104,"slug":105},9,"Religion & Spirituality",20,"religion-spirituality",{"id":104,"doc_module":4,"doc_module_name":42,"category_name":107,"show_sort_weight":104,"slug":108},"World Cup","world-cup",{"id":110,"doc_module":4,"doc_module_name":42,"category_name":111,"show_sort_weight":110,"slug":112},10,"Lifestyle","lifestyle",{"id":114,"doc_module":4,"doc_module_name":42,"category_name":115,"show_sort_weight":84,"slug":116},19,"General","general"]