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These frameworks, while addressing longstanding racial inequities, often miss infection-, geography-, and early-life–driven malignancies that are well defined in global cancer epidemiology. As migration reshapes disease distribution, persistent prevention gaps arise among immigrant and diaspora populations. The perspective integrates nativity, early-life exposure, and transnational determinants into prevention design, using gastric cancer as a case study.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/migration-informed-cancer-equity-a-global-perspective/350346/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/migration-informed-cancer-equity-a-global-perspective/350346.png","ImageObject",300,407,{"name":92,"@type":93},"Adam","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-09-23","2026-09-22",true,{"@type":102,"interactionType":103,"userInteractionCount":14},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why do US cancer-prevention frameworks often fail to capture certain cancer risks?","Question",{"text":112,"@type":113},"They are largely shaped by domestic policy histories and nationally bounded concepts of disparity, which can overlook malignancies driven by infection, geography, and early-life exposure.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How does migration affect cancer equity in the United States?",{"text":117,"@type":113},"Migration reshapes population composition, leaving migration-linked risks incompletely captured by existing surveillance and prevention frameworks, so prevention gaps persist among immigrant and diaspora groups.",{"name":119,"@type":110,"acceptedAnswer":120},"What is the paper’s proposed solution for improving cancer equity?",{"text":121,"@type":113},"A migration-informed approach that integrates nativity, early-life exposure, and transnational determinants into prevention design, enabling risk-based stratification and targeted intervention across the life course.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},350346,1790198689,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":14,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":34,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},1374404737137,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Migration-Informed Cancer Equity: A Global Perspective  \nCHUL S. HYUN  \n*Author affiliations can be found in the back matter of this article   \nABSTRACT  \nHealth equity is now a central aim of modern medicine, yet US cancer-prevention frameworks remain largely shaped by domestic policy histories and nationally bounded conceptions of disparity. While essential for addressing longstanding racial inequities, these frameworks often overlook malignancies driven by infection, geography, and early-life exposure—risks that are well characterized in global cancer epidemiology but imperfectly translated into domestic prevention strategies. As migration reshapes disease distribution, this misalignment leaves persistent gaps in the prevention of cancers such as gastric, liver, and cervical cancer among immigrant and diaspora populations. This perspective advances a migration-informed approach to cancer equity that integrates nativity, early-life exposure, and transnational determinants into prevention design. Using gastric cancer as a case study, we show how omission of migration-linked risk contributes to systematic under-recognition of high-risk populations in low-incidence countries, despite strong global evidence for effective prevention. Achieving meaningful cancer equity in the twenty-first century will require frameworks that extend beyond national borders and reflect how cancer risk is distributed in an increasingly mobile world.  \nVIEWPOINTS  \nCORRESPONDING AUTHOR:  \nChul S. Hyun  \nSection of Digestive Diseases, Department of Medicine, Yale School of Medicine, Yale University, New Haven, CT 06510, USA; Yale School of Public Health, Yale University, New Haven, CT 06510, USA  \n[chul.hyun@yale.edu](chul.hyun@yale.edu)  \nKEYWORDS:  \ncancer equity, migration and health, infection-related cancers, gastric cancer prevention, global cancer epidemiology, risk-based prevention  \nTO CITE THIS ARTICLE:  \nHyun CS. Migration-Informed Cancer Equity: A Global Perspective. Annals of Global Health. 2026; 92(1): 48, 1–  \n7. DOI: [https://doi.org/10.5334/](https://doi.org/10.5334/)[ ](https://doi.org/10.5334/)[aogh.5189](aogh.5189)  \nINTRODUCTION  \nUS health-equity frameworks have been shaped by a specific historical mandate: to confront injustice produced within national borders. Emerging from the civil-rights movement and formalized through federal efforts such as the 1985 Heckler Report [1], these approaches have appropriately focused on racial and ethnic inequities rooted in domestic social, economic, and healthcare systems [2, 3] . They remain foundational to public health policy, research priorities, and clinical practice.  \nMore recently, the concept of structural racism has further strengthened this orientation by reframing inequity as a systemic property of institutions rather than individual prejudice. Health outcomes are now understood as the cumulative result of interlocking systems, including housing, education, employment, healthcare, and criminal justice, that differentially distribute risk and opportunity [4, 5]. This framework has been indispensable in clarifying how inequity is reproduced within US society and in motivating reforms across multiple sectors [6, 7] .  \nAt the global level, cancer prevention efforts have long shared a concern with inequity and unequal access to health-promoting conditions, but they have emphasized a complementary set of determinants. Initiatives led by the World Health Organization (WHO) and the International Agency for Research on Cancer (IARC) have foregrounded how cancer risk is shaped by geography, early-life conditions, and environmental and infectious exposures, particularly in low- and middle-income settings. This perspective has highlighted malignancies linked to Helicobacter pylori, hepatitis B virus, and human papillomavirus as preventable consequences of the place and timing of exposure [8–11]. As a result, global prevention strategies have prioritized population-level interventions such as ","cbCairzH64MZXU4t","https://ap.wps.com/l/cbCairzH64MZXU4t","pdf",249901,"English","# Abstract\n# Viewpoints\n# Introduction","[{\"question\":\"Why do US cancer-prevention frameworks often fail to capture certain cancer risks?\",\"answer\":\"They are largely shaped by domestic policy histories and nationally bounded concepts of disparity, which can overlook malignancies driven by infection, geography, and early-life exposure.\"},{\"question\":\"How does migration affect cancer equity in the United States?\",\"answer\":\"Migration reshapes population composition, leaving migration-linked risks incompletely captured by existing surveillance and prevention frameworks, so prevention gaps persist among immigrant and diaspora groups.\"},{\"question\":\"What is the paper’s proposed solution for improving cancer equity?\",\"answer\":\"A migration-informed approach that integrates nativity, early-life exposure, and transnational determinants into prevention design, enabling risk-based stratification and targeted intervention across the life course.\"}]","Migration-Informed Cancer Equity - A Global Perspective | PDF",1790088572,18]