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This study uses real-world multicenter data to compare outcomes in cSDH patients treated with surgery alone versus surgery combined with MMAE. Methods A multi-institutional, multinational retrospective propensity-matched analysis used the TriNetX platform and evaluated readmission, need for repeat surgery, and 6-month mortality. Results and conclusion MMAE with surgical evacuation was associated with reduced mortality and lower readmission and reoperation rates.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/middle-meningeal-artery-embolization-with-surgical-evacuation-improves-outcomes-in-chronic-subdural-hematoma-original-research/440423/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/middle-meningeal-artery-embolization-with-surgical-evacuation-improves-outcomes-in-chronic-subdural-hematoma-original-research/440423.png","ImageObject",300,407,{"name":92,"@type":93},"jayni","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the purpose of combining middle meningeal artery embolization with surgery for chronic subdural hematoma?","Question",{"text":112,"@type":113},"The study evaluates whether adding MMAE to surgical evacuation improves outcomes compared with surgery alone in real-world patients with cSDH.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the study designed and what dataset was used?",{"text":117,"@type":113},"It was a multi-institutional, multinational retrospective propensity-matched study using the TriNetX platform to compare surgical evacuation plus MMAE versus surgery alone.",{"name":119,"@type":110,"acceptedAnswer":120},"Which outcomes were assessed to compare the two treatment strategies?",{"text":121,"@type":113},"The study assessed inpatient readmission, the need for repeat surgery, and mortality at 6 months after treatment.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},440423,1790789532,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},3985747859343,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","New devices and techniques  \n1Department of Neuroradiology, West Virginia University Rockefeller Neuroscience Institute, Morgantown, West Virginia, USA  \n2Department of Neurosurgery, West Virginia University Rockefeller Neuroscience Institute, Morgantown, West Virginia, USA  \nCorrespondence to  \nDr Dhairya A Lakhani; [dhairyalakhan](dhairyalakhani@gmail.com)[i@gmail.com](dhairyalakhani@gmail.com)  \nReceived 12 December 2024 Accepted 3 January 2025  \n© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.  \nTo cite: Lakhani DA, Balar AB, Boo SH, et al. J NeuroIntervent Surg Epub ahead of print: [please include Day Month Year] . doi:10 . 1136/jnis-2024- 022932  \nOriginal research  \nMiddle meningeal artery embolization with surgical evacuation improves outcomes in chronic subdural hematoma: a multi-institutional and multinational database study  \nDhairya A Lakhani  , 1 Aneri B Balar, 1 SoHyun Boo  , 1 Sanjay Bhatia,2 Ansaar T Rai  1  \nABSTRACT:  \nBackground Middle meningeal artery embolization (MMAE) is emerging as a promising adjunctive treatment in patients with chronic subdural hematomas (cSDH) . This study presents real world multicenter data comparing outcomes in cSDH patients undergoing surgical treatment alone or combined with MMAE.  \nMethods This multi-institutional, multinational, retrospective, propensity-matched study utilized the TriNetX platform to compare outcomes in patients undergoing surgical evacuation and MMAE versus surgery alone for cSDH. The outcomes included inpatient readmission, need for repeat surgery, and mortality at 6 months following treatment.  \nResults Among 253 108 patients with cSDH, 14 568 underwent surgical evacuation and 711 underwent surgical evacuation with MMAE. Patients who underwent surgical evacuation alone had higher odds of unplanned readmission, need for repeat surgery, and mortality at 6 months, both before and after propensity score matched analysis.  \nConclusion Patients undergoing MMAE with surgical evacuation for cSDH had reduced mortality along with reduced rates of readmission and reoperation, suggesting MMAE as a valuable adjunct in managing cSDH.  \nINTRODUCTION  \nA chronic subdural hematoma (cSDH) is one of the most common causes of neurosurgical admissionsin patients aged over 65 years1 and is a sentinel health event often leading to a cascade of disability and repeat admissions.2 Recent randomized clinical trials have shown a favorable treatment effect of middle meningeal artery embolization (MMAE) over standard of care.3–5 The typical surgical management options include craniotomy with burr hole drainage or craniectomy, and more recently less invasive percutaneous drain systems.2 6  \nThe nationwide 30-day readmission rate following craniotomy is 21.7%(10 643 out of 49 013 patients).7 Similarly, the nationwide 30-day readmission rate following burr hole craniotomy is 24.5%(675 out of 2753 patients).8 Retreatment rates for both craniotomy and burr hole craniotomyare relatively low, with patients in the burr hole cohort showing a slightly higher rate of retreatment  \n\n| WHAT IS ALREADY KNOWN ON THIS TOPIC |\n| --- |\n| ⇒ Previous studies and ongoing clinical trials have demonstrated the potential benefits of middle meningeal artery embolization (MMAE) in managing chronic subdural hematomas (cSDH) . While MMAE has been shown to reduce recurrence and improve outcomes when combined with surgery, it is not yet a universally adopted adjunctive treatment in clinical practice.\u003Cbr>WHAT THIS STUDY ADDS |\n| ⇒ This study provides robust, real-world, multiinstitutional, and multinational data comparing outcomes of patients with cSDH undergoing surgery alone to those receiving surgery combined with MMAE. The findings show that MMAE improves clinical outcomes by reducing unplanned readmission rates, the need for repeat surgeries, and mortality at 6 months post-treatment.\u003Cbr>HOW THIS STUDY MIGHT AFFECT","cbCaiqv7xQTdMIz5","https://ap.wps.com/l/cbCaiqv7xQTdMIz5","pdf",274393,"English","# Abstract\n# Introduction\n# What is already known on this topic\n# What this study adds\n# How this study might affect research, practice or policy","[{\"question\":\"What is the purpose of combining middle meningeal artery embolization with surgery for chronic subdural hematoma?\",\"answer\":\"The study evaluates whether adding MMAE to surgical evacuation improves outcomes compared with surgery alone in real-world patients with cSDH.\"},{\"question\":\"How was the study designed and what dataset was used?\",\"answer\":\"It was a multi-institutional, multinational retrospective propensity-matched study using the TriNetX platform to compare surgical evacuation plus MMAE versus surgery alone.\"},{\"question\":\"Which outcomes were assessed to compare the two treatment strategies?\",\"answer\":\"The study assessed inpatient readmission, the need for repeat surgery, and mortality at 6 months after treatment.\"}]","Middle meningeal artery embolization with surgical evacuation improves outcomes in chronic subdural hematoma - original research | PDF",1790692162,13]