[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-638992-105":59,"doc-detail-638992-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","metamo-pro-product-information-from-herbs-to-skin","Metamo PRO - Product Information - From Herbs To Skin","","Metamo PRO is a plant-origin skin and hair care ingredient extracted from Plantago asiatica using J2K METACARE technology. It contains Plantamajoside and is designed to enhance hair growth factor activation by promoting KGF, VEGF, FGF2 and increasing expression of β-catenin and CREB in hair-related cells. In-vitro angiogenesis and clinical shampoo tests indicate improved hair fall reduction and increased hair root thickness after 12 weeks. The product specification includes wash-off and leave-on hair care applications.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/metamo-pro-product-information-from-herbs-to-skin/638992/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/metamo-pro-product-information-from-herbs-to-skin/638992.png","ImageObject",300,407,{"name":92,"@type":93},"Mafia Boss","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-09","2026-10-22",true,{"@type":102,"interactionType":103,"userInteractionCount":81},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is Metamo PRO made from and what is its main active component?","Question",{"text":112,"@type":113},"Metamo PRO is extracted from Plantago asiatica using J2K METACARE technology. It contains Plantamajoside, which supports activation of hair growth factors.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What in-vitro results does Metamo PRO show for hair-related markers?",{"text":117,"@type":113},"Metamo PRO dose-dependently increased expression of KGF, VEGF, and FGF2, and also increased CREB and β-catenin expression in hair dermal papilla cells.",{"name":119,"@type":110,"acceptedAnswer":120},"How effective is Metamo PRO in the clinical shampoo test?",{"text":121,"@type":113},"After 12 weeks using Shampoo B containing 3% Metamo PRO, hair fall reduction improved by 78.80%, and hair root thickness improved by 25.21%.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},638992,1792701037,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":81,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":19,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":129,"read_time":52,"preview_page_count":4},962090760730,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc","Metamo PRO  \n\\#HairGrowthPromotion \\#PlantOrigin \\#Plantamajoside  \nFrom Herbs To Skin  \nMetamo PRO  \nGeneral Information  \nINCI Name : Plantago Asiatica Extract  \nPlantago asiatica is a self-fertile, perennial herb that can grow even in barren environments where ordinary plants find it difficult to thrive. Metamo PRO, an ingredient for skin and hair care, is extracted using J2K METACARE technology. Metamo PRO contains Plantamajoside, which enhances the activation of hair growth factors. Additionally, METAMO PRO can promote hair growth by increasing the expression of β-catenin and CREB.  \nEfficacy Evaluation (In-vitro)  \nGrowth Factors expression promotion ※ On Human Hair Follicle Dermal Papilla Cells  \nRe lative mRNA Expression(%)  \n150  \n100  \n50  \n0  \n\n| |    *\u003Cbr>\u003Cbr>|   *\u003Cbr>|\n| --- | --- | --- |\n| \u003Cbr>|  |  |\n|  |  |  |\n\n* * *  \n**  \nKGF VEGF FGF2 *  \n0. 1%  \n2.5%  \n0.5%  \n1ppm  \n0. 1%  \n2.5%  \n0.5%  \n0. 1%  \n2.5%  \n0.5%  \nControl  \n1ppm  \nControl  \n1ppm  \n└ Metamo PRO ┘ Minoxidil └ Metamo PRO ┘ Minoxidil └ Metamo PRO ┘ Minoxidil  \nMetamo PRO dose-dependently increased the expression of KGF, VEGF and FGF2 in hair dermal papilla cells.  \nPromotion of Growth Factors Expression ※ On Human Hair Germinal Matrix Cells  \n└ Metamo PRO ┘ Minoxidil └ Metamo PRO ┘ Minoxidil └ Metamo PRO ┘ Minoxidil  \nMetamo PRO dose-dependently increased the expression of CREB and β-Catenin in hair dermal papilla cells. Also, dose-dependently increased the expression of MYC in hair dermal papilla cells in hair follicle stem cells.  \nMetamo PRO  \nEfficacy Evaluation (In-vitro)  \nAngiogenesis Effect ※ On Human Umbilical Vein Endothelial Cells  \nTube formation(% of control)  \n180  \n150  \n120  \n30  \n43 16%  \n90  \n60  \n0  \n\n| .\u003Cbr>* |  |  |  |\n| --- | --- | --- | --- |\n|  |  | |  |\n| |  |  |  |\n| l |  |  |  |\n| ntro\u003Cbr>025% | 05% |  | 1% |\n| Co\u003Cbr>0. | 0. |  | 0. |\n\n└ Metamo PRO ┘  \nMetamo PRO dose-dependently increased the expression of new blood vessels  \nClinical Test  \nHair Fall Reduction  \nBefore Use  \nAfter 4 Weeks  \nAfter 8 Weeks  \nAfter 12 Weeks  \nShampoo A (Control Group)  \n Shampoo B (Test Group)  \nAfter 12 weeks of using Shampoo B, which contains Metamo PRO hair fall reduction was improved by 78. 80%  \n*Shampoo B contains 3% of Metamo PRO  \nHair Root Thickness Improvement  \nBefore Use  \nAfter 4 Weeks  \nAfter 8 Weeks  \nAfter 12 Weeks  \n(%) 0 20  \n40 60 80 100 120 140 (%)  \n Shampoo A (Control Group)  \n Shampoo B (Test Group)  \nAfter 12 weeks of using Shampoo B, which contains Metamo PRO hair root thickness was improved by 25. 21%  \n*Shampoo B contains 3% of Metamo PRO  \nFrom Herbs To Skin  \nMetamo PRO  \nProduct Information  \nMetamo PRO  \nSpecification  \nApplication  \nOther Benefits  \nActive ingredient for hair growth promotion  \nINCI Names  \nAppearance Odor  \npH (25℃)  \nRelative Density at 25℃  \nButylene Glycol, Water, Plantago Asiatica Extract Yellow to dark yellow liquid Characteristic  \n3.0 ~ 6.0  \n0.990 ~ 1.040  \nWash-off and leave-on products for hair care Hair growth promotion products  \nChina IECIC (Inventory of Existing Cosmetic Ingredients in China) listed Paper published on the Journal of cosmetic science in 2023  \nEWG Grade 1  \nThis material is produced based on our current knowledge and test results. This material is only to give the information related with the product and it should not be used for other purposes by any third party. The copyright of this material is subject to J2KBIO Co., Ltd. Any kind of reproduction, reconstitution or amendment of this material without our prior consent is prohibited, and we do not bear any liability for such unauthorized activities. The content in this material may be changed, amended or deleted without prior notice.  \nJ2KBIO Co., Ltd.,  \nSep., 2024  \nFrom Herbs To Skin  \n50-3 Dureungyuri-ro, Ochang, Cheongwon, Cheongju, Chungbuk, 28104 Korea  \nT : +82.43.280.9030 / F : +82.43.280.9099 [www.j2kbio.com](www.j2kbio.com)  \n[care@j2kbio.com](care@j2kbio.com)","cbCaihz2nSnhUt0L","https://ap.wps.com/l/cbCaihz2nSnhUt0L","pdf",731256,"English","# General Information\n# Efficacy Evaluation (In-vitro)\n## Growth Factors Expression Promotion\n## Angiogenesis Effect\n# Clinical Test\n## Hair Fall Reduction\n## Hair Root Thickness Improvement\n# Product Information\n## Specification\n## Application\n## Other Benefits","[{\"question\":\"What is Metamo PRO made from and what is its main active component?\",\"answer\":\"Metamo PRO is extracted from Plantago asiatica using J2K METACARE technology. It contains Plantamajoside, which supports activation of hair growth factors.\"},{\"question\":\"What in-vitro results does Metamo PRO show for hair-related markers?\",\"answer\":\"Metamo PRO dose-dependently increased expression of KGF, VEGF, and FGF2, and also increased CREB and β-catenin expression in hair dermal papilla cells.\"},{\"question\":\"How effective is Metamo PRO in the clinical shampoo test?\",\"answer\":\"After 12 weeks using Shampoo B containing 3% Metamo PRO, hair fall reduction improved by 78.80%, and hair root thickness improved by 25.21%.\"}]","Metamo PRO - Product Information - From Herbs To Skin | PDF"]