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This case series reports two patients with pelvic masses suspicious for adnexal neoplasm, managed surgically with complete resection. Pathology confirmed mesenteric–retroperitoneal mucinous cystic neoplasm in both cases. Notably, both patients had diverticulosis, and perioperative diverticulitis complicated their course, prompting evaluation of a potential correlation between diverticular disease and histopathology.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/mesenteric-and-retroperitoneal-mucinous-cystic-neoplasms-a-nongynecologic-process-commonly-managed-by-gynecologic-oncologists/355170/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/mesenteric-and-retroperitoneal-mucinous-cystic-neoplasms-a-nongynecologic-process-commonly-managed-by-gynecologic-oncologists/355170.png","ImageObject",300,407,{"name":92,"@type":93},"Miles","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-22",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why are mesenteric–retroperitoneal mucinous cystic neoplasms difficult to study?","Question",{"text":112,"@type":113},"They are rare, and available evidence on diagnosis and treatment is limited, largely based on case reports and case series.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were the two patients managed in the reported cases?",{"text":117,"@type":113},"Both presented with pelvic masses suspicious for an adnexal neoplasm and were treated surgically with complete resection of the suspected tumor.",{"name":119,"@type":110,"acceptedAnswer":120},"What complication was uniquely observed in both patients?",{"text":121,"@type":113},"Both patients had diverticulosis, and their perioperative course was complicated by diverticulitis.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},355170,1790179153,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},13056703019404,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","Case Reports in Obstetrics and Gynecology  \nCASE REPORT  OPEN ACCESS   \nMesenteric and Retroperitoneal Mucinous Cystic Neoplasms: A Nongynecologic Process Commonly Managed by Gynecologic Oncologists  \nJudy Hayek1 | Jennifer Wolf1 | Alexandra Hamilton2 | Yong Mei Yin3 | Margaux J. Kanis4  \n1Division of Gynecologic Oncology, Maimonides/SUNY Downstate Health Sciences University, Brooklyn, New York, USA | 2Department of Obstetrics and Gynecology, NewYork-Presbyterian (NYP) Brooklyn Methodist Hospital, Brooklyn, New York, USA | 3Department of Pathology, NewYork-Presbyterian (NYP) Brooklyn Methodist Hospital, Brooklyn, New York, USA | 4Division of Gynecologic Oncology, NewYork-Presbyterian (NYP) Brooklyn Methodist Hospital, Brooklyn, New York, USA  \nCorrespondence: Judy Hayek ([j.hayek92@gmail.com](j.hayek92@gmail.com))  \nReceived: 11 February 2025 | Revised: 1 December 2025 | Accepted: 15 December 2025  \nAcademic Editor: Seung-Yup Ku  \nKeywords: diverticulitis | mesenteric–retroperitoneal | mucinous cystic | pelvic mass  \nABSTRACT  \nRetroperitoneal mucinous cystic neoplasm is a rare pathology. Data regarding diagnosis and treatment are limited and based on case reports and series. We describe a case series of two patients each presenting with a pelvic mass suspicious for an adnexal neoplasm. Both were treated surgically with complete resection of the suspected tumor. Pathology from both specimens revealed mesenteric–retroperitoneal mucinous cystic neoplasm. Uniquely, both patients had diverticulosis and their perioperative course was complicated by diverticulitis. We investigate a possible correlation between diverticular disease and the histopathology of mesenteric retroperitoneal mucinous cystic neoplasms.  \n1 | Introduction  \nMucinous cystic neoplasms have most frequently been described arising in the pancreas and liver [1–5] with rare case reports of tumors arising in the retroperitoneum or mesentery [6–9] . These tumors are composed of mucinous epithelium and are most often described as low-grade dysplasia or low malignant potential. They have been described in both males and female patients [5]; in women, they differ from other benign mucinous tumors due to their ovarian-like stroma [6], but have been described by a variety of names in case reports, limiting comparisons. Of the nonpancreatic and hepatic/biliary reports, most are described as originating from the retroperitoneum, with a few originating from the rectal muscularis propria [9], transverse colon mesentery [6], sigmoid mesentery [8], and periappendiceal mesentery versus mesoappendix [5] . No reports of connections to the bowel lumen or postoperative complications have been described. Here, we describe two cases of mucinous cystic  \nneoplasms arising from the retroperitoneum or mesentery in which the patient's course was complicated by diverticulitis. All the patients allowed personal data processing, and informed consent was obtained from all individual participants included in the study.  \n2 | Case Presentations  \n2.1 | Case 1 (1401515970)  \nAn 83-year-old who had previously undergone total abdominal hysterectomy 50 years prior for fibroid uterus was sent to the hospital by her primary care physician due to severe hypertension, where she was incidentally found to have a 20-cm pelvic mass. Bilateral percutaneous nephrostomy tubes were placed due to extrinsic compression of the ureters. She was subsequently referred to gynecologic oncology, and CT of the abdomen and  \nThis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.  \nCopyright © 2026 Judy Hayek et al. Case Reports in Obstetrics and Gynecology published by John Wiley & Sons Ltd.  \nCase Reports in Obstetrics and Gynecology, 2026; 2026:7921200 1 of 5  \n[https://doi.org/10.1155/crog/7921200](https://doi.org/10.1155/crog/7921200)  \n(a) (b)  \nFIGURE 1 | (a) Case 1: CT ab","cbCaieZVy2q5ss3w","https://ap.wps.com/l/cbCaieZVy2q5ss3w","pdf",2615619,"English","# Abstract\n# Introduction\n# Case Presentations\n## Case 1\n## Case 2","[{\"question\":\"Why are mesenteric–retroperitoneal mucinous cystic neoplasms difficult to study?\",\"answer\":\"They are rare, and available evidence on diagnosis and treatment is limited, largely based on case reports and case series.\"},{\"question\":\"How were the two patients managed in the reported cases?\",\"answer\":\"Both presented with pelvic masses suspicious for an adnexal neoplasm and were treated surgically with complete resection of the suspected tumor.\"},{\"question\":\"What complication was uniquely observed in both patients?\",\"answer\":\"Both patients had diverticulosis, and their perioperative course was complicated by diverticulitis.\"}]","Mesenteric and Retroperitoneal Mucinous Cystic Neoplasms: A Nongynecologic Process Commonly Managed by Gynecologic Oncologists | PDF",1790116488,13]