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Mathias Grote traces shifting concepts of membranes, from early molecular-mechanical visions of life to the rise of instruments, metaphors, and experimental techniques that made cellular processes tangible. The book connects membrane dynamics, pumps, receptors, and transducers with case studies spanning different places and decades, linking molecular mechanisms to broader philosophical and scientific epistemology. Extensive references and an index support the analysis of molecular biology research and its history.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":15,"@type":76,"position":81},"https://docshare.wps.com/document/literature/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/membranes-to-molecular-machines-active-matter-and-the-remaking-of-life/296482/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/membranes-to-molecular-machines-active-matter-and-the-remaking-of-life/296482.png","ImageObject",300,407,{"name":92,"@type":93},"Logic","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-18",true,{"@type":102,"interactionType":103,"userInteractionCount":81},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the central subject of Membranes to Molecular Machines?","Question",{"text":112,"@type":113},"It studies how membranes and active matter are connected to the development of molecular machines and the reworking of life at the molecular level.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How does the book organize its historical discussion?",{"text":117,"@type":113},"It moves from an introduction on molecular-mechanical ideas of life into Part One that focuses on taking membranes apart and isolating molecular pumps, followed by chapters on active matter.",{"name":119,"@type":110,"acceptedAnswer":120},"Which topics are highlighted in the early chapters?",{"text":121,"@type":113},"The early sections address membrane boundaries and structure, membrane dynamics, black-box interpretations of membranes, and the roles of pumps, transducers, receptors, and molecular mechanisms.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},296482,1792180047,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":14,"category_name":15,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":81,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},1099513958762,"https://ap-avatar.wpscdn.com/avatar/1000023916a998db790?x-image-process=image/resize,m_fixed,w_180,h_180&k=1784791008015729253","Copyright 2019. University of Chicago Press. .All rights reserved May not be reproduced in any form without permission from the publisher, except fair uses permitted under U .S . or applicable copyright law .  \nEBSCO Publishing : eBook Collection (EBSCOhost) -printed on 2/13/2023 7:00 AM via  \nAN: 1941159 ; Mathias Grote . ; Membranes to Molecular Machines : Active Matter and the Remaking of Life  \nAccount: ns335141  \nMembranes to Molecular Machines  \nEBSCOhost -printed on 2/13/2023 7:00 AM via . All use subject to [https://www.ebsco.com/terms-of-use](https://www.ebsco.com/terms-of-use)  \nSynthesis  \nA series in the history of chemistry, broadly construed, edited by Carin Berkowitz, Angela N. H. Creager, John E. Lesch, Lawrence M. Principe, Alan Rocke, and E. C. Spary, in partnership with the Science History Institute  \nEBSCOhost -printed on 2/13/2023 7:00 AM via . All use subject to [https://www.ebsco.com/terms-of-use](https://www.ebsco.com/terms-of-use)  \nMembranes to Molecular Machines:  \nActive Matter and the Remaking of Life  \nMathias Grote  \nThe University of Chicago Press :: Chicago and London  \nEBSCOhost -printed on 2/13/2023 7:00 AM via . All use subject to [https://www.ebsco.com/terms-of-use](https://www.ebsco.com/terms-of-use)  \nThe University of Chicago Press, Chicago 60637  \nThe University of Chicago Press, Ltd., London  \n© 2019 by The University of Chicago  \nAll rights reserved. No part of this book may be used or reproduced in any manner whatsoever without written permission, except in the case of brief quotations in critical articles and reviews. For more information, contact the University of Chicago Press, 1427 E. 60th St., Chicago, IL 60637.  \nPublished 2019  \nPrinted in the United States of America  \n28 27 26 25 24 23 22 21 20 19 1 2 3 4 5  \nisbn-13: 978-0-226-62515-7 (cloth)  \nisbn-13: 978-0-226-62529-4 (e-book)  \ndoi: [https://doi.org/](https://doi.org/10.7208/chicago/9780226625294.001.0001)[10.7208](https://doi.org/10.7208/chicago/9780226625294.001.0001)[/chicago/](https://doi.org/10.7208/chicago/9780226625294.001.0001)[9780226625294](https://doi.org/10.7208/chicago/9780226625294.001.0001)[.](https://doi.org/10.7208/chicago/9780226625294.001.0001)[001](https://doi.org/10.7208/chicago/9780226625294.001.0001)[.](https://doi.org/10.7208/chicago/9780226625294.001.0001)[0001](https://doi.org/10.7208/chicago/9780226625294.001.0001)  \n[Library of Congress Cataloging-in-Publication Data](Library of Congress Cataloging-in-Publication Data)  \n[Names: Grote](Names: Grote), [Mathias](Mathias), author.  \nTitle: Membranes to molecular machines : active matter and the remaking of life / Mathias Grote.  \nDescription: Chicago : The University of Chicago Press, 2019. | Includes  \nbibliographical references and index.  \nIdentifiers: LCCN 2018044853 | isbn 9780226625157 (cloth : alk. paper) |  \nisbn 9780226625294 (e-book)  \nSubjects: LCSH: Molecular biology—Research—History. | Membranes (Biology)—Research—History. | Biotechnology—Research—History.  \nClassification: LCC QH506 .G768 2019 | DDC 572.8—dc23  \nLC record available at [https://lccn.loc.gov/2018044853](https://lccn.loc.gov/2018044853)  \n♾ This paper meets the requirements of ansi/niso Z39.48-1992 (Permanence of Paper) .  \nEBSCOhost -printed on 2/13/2023 7:00 AM via . All use subject to [https://www.ebsco.com/terms-of-use](https://www.ebsco.com/terms-of-use)  \nTo my parents, who taught me to look at small things  \nEBSCOhost -printed on 2/13/2023 7:00 AM via . All use subject to [https://www.ebsco.com/terms-of-use](https://www.ebsco.com/terms-of-use)  \nd’alembert: [ . . . ] Si c’est une qualité générale de la matière, il faut que la pierre sente.  \ndiderot: Pourquoi non?  \nd’alembert: Cela est dur à croire.  \ndiderot: Oui, pour celui qui la coupe, la taille, la broue et quine l’entend pas crier.  \nDenis Diderot, Entretien entre Diderot et d’Alembert, 1769.  \nEBSCOhost -printed on 2/13/2023 7:00 AM via . All use subject to [https://www.ebsco.com/terms-of-use](https://www","cbCairPnxZlN3p4O","https://ap.wps.com/l/cbCairPnxZlN3p4O","pdf",4350013,307,"English","# Preface\n# Introduction: The Molecular-Mechanical Vision of Life\n## Descarts among the X-ray machines? Mechanisms, molecular machines, and the epistemology of science\n## Life and matter—another history of the molecular life sciences after 1970\n## Constitutive and exemplary: Bacteriorhodopsin, membranes, and the rise of molecular machinery\n## A note on people and places, times and sources\n## Outline of the book\n# Part One: Taking Membranes Apart, Isolating a Molecular Pump\n## What Membranes Can Tell a Historian and Philosopher of the Life Sciences\n## The cell’s elusive boundaries and the molecular age\n## Neglected dimensions: Membrane structure\n## “The riddle of surface action”—membrane dynamics\n## Membranes as black boxes\n## Pumps and transducers—metaphors in search of a substrate\n## Receptors and transducers, or materializations of cellular communication in the cybernetic age\n## Proteins and the promise of molecular mechanisms\n## The membrane frontier\n## Conclusion\n## 2 Active Matter","[{\"question\":\"What is the central subject of Membranes to Molecular Machines?\",\"answer\":\"It studies how membranes and active matter are connected to the development of molecular machines and the reworking of life at the molecular level.\"},{\"question\":\"How does the book organize its historical discussion?\",\"answer\":\"It moves from an introduction on molecular-mechanical ideas of life into Part One that focuses on taking membranes apart and isolating molecular pumps, followed by chapters on active matter.\"},{\"question\":\"Which topics are highlighted in the early chapters?\",\"answer\":\"The early sections address membrane boundaries and structure, membrane dynamics, black-box interpretations of membranes, and the roles of pumps, transducers, receptors, and molecular mechanisms.\"}]","Membranes to Molecular Machines - Active Matter and the Remaking of Life | PDF",1789733022,473]