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It emphasizes that the monograph is not a review but a direct experimental record, beginning with observations on repeated injections of horse serum in rabbits and connected to the Arthus Phenomenon and Richet’s anaphylaxis. It also highlights the freshness of Arthus’ philosophical preface, prompted by a physician’s question, and notes the translation effort by Henry E. Sigerist with publication by The Johns Hopkins Press in 1943.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/maurice-arthus-philosophy-of-scientific-investigation-preface-foreword/422399/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/maurice-arthus-philosophy-of-scientific-investigation-preface-foreword/422399.png","ImageObject",300,407,{"name":92,"@type":93},"\tCallum ","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main purpose of the monograph by Maurice Arthus, as described in the foreword?","Question",{"text":112,"@type":113},"It records a direct experimental attack on the problem rather than serving as a review of current information. The work traces original observations related to repeated injections of horse serum in rabbits.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Why is Arthus’ preface described as especially fresh and appealing?",{"text":117,"@type":113},"The foreword links it to a personal circumstance: Arthus received a question from a young physician and chose to answer it by presenting his own experimental account along with an essay on the philosophy of scientific investigation.",{"name":119,"@type":110,"acceptedAnswer":120},"How did the translation become available to readers, according to the foreword?",{"text":121,"@type":113},"A translation was contemplated but did not materialize until Henry E. Sigerist suggested the task to Dr. Sigerist. With his enthusiasm and kindness, the preface was made readily available, with publication by the Johns Hopkins Press in 1943.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},422399,1790820554,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":36,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},137451211410,"https://ap-avatar.wpscdn.com/avatar/2000bb0a9246f588df?x-image-process=image/resize,m_fixed,w_180,h_180&k=1786362646172706240","# MAURICE ARTHUS'\n\nPHILOSOPHY OF SCIENTIFICINVESTIGATION  \nPREFACE TO De PAnaphylaxie à PImmunité,PARIS,1921  \nTRANSLATED FROM THE FRENCH,WITH AN INTRODUCTION BYHENRY E.SIGERIST  \nFOREWORD BY  \nWARFIELD T.LONGCOPE  \nBALTIMORETHE JOHNS HOPKINS PRESS  \n1943  \nhttps://archive.org/details/philosophyofscie0000unse_s3v8  \n 4geus   \n500的下时  \n# MAURICE ARTHUS'\n\nPHILOSOPHY OF SCIENTIFICINVESTIGATION  \nPREFACE TO De I'Anaphylaxie à VImmunité,PARIS,1921  \nTRANSLATED FROM THE FRENCH,WITH AN INTRODUCTION BYHENRY E.SIGERIST  \nFOREWORD BY  \nWARFIELD T.LONGCOPE  \nBALTIMORETHE JOHNS HOPKINS PRESS  \n1943  \nReprinted from Bulletin of the History of Medicine,Volume XIV,Number 3,October,1943,pages 366-390.  \nFOREWORD  \nIt is now more than 20 years since the French physiologist,Maurice Arthus,published a book,the title of which was“DePAnaphylaxie à I'Immunité.”At that time the monograph was anotable contribution to the subject,for Arthus was one of thepioneers in this particular field of investigation.His book is not areview of current information upon the subject,as he takes pains topoint out,but the record of a direct experimental attack upon theproblem.This starts with his original observations upon the reac-tion to repeated injections of horse serum in the rabbit;and,sincethe“Arthus Phenomenon\"and the“Anaphylaxis”of Richet aretwo phenomena of fundamental significance,the text remainshistorically important.  \nThere is,however,another reason why the treatise should not beforgotten,for it is introduced by a preface which is as fresh andappealing today as it was at the time it was written.An explanationfor this preface is to be found in an interesting little circumstancethat led Arthus to write the monograph itself.He received a letterone day from a young physician asking,“Mais qu'est-ce donc queI'anaphylaxie?”Arthus thought the question could best be answeredby preparing an account of his own experiments;and as an in-troduction he wrote an essay upon the philosophy of scientificinvestigation.  \nThis intimate and charming address of the master to his pupilsis a bit of medical literature which is worthy of being preserved.There is certainly nothing novel in the topic,but Arthus approachesit in such an unusual manner,and with such full understanding ofthe pitfalls that lie in the path of the unwary student,that the essayacquires a unique quality.In its own way it compares well withthe celebrated“Introduction à I'Etude de la Médecine Expéri-mentale”of Claude Bernard,though Arthus has condensed whathe has to say in comparatively few pages.He says this,however,inbeautiful French,with feeling,\"esprit\"and great wisdom.  \nThe book is now difficult to obtain in this country,for it is not to  \nbe found in some of the largest medical libraries.For many yearsit has seemed desirable that this delightful preface should be betterknown.A translation was contemplated but never materializeduntil the suggestion was made to Dr.Sigerist.With his quickappreciation and enthusiasm he immediately consented to under-take this rather delicate and difficult task,and now through hiskindness it is possible to make this unique piece of medical literaturereadily available.It is hoped that all who read it may derive pleasureand profit from it.  \nWARFIELD T.LONGCOPE","cbCaiq70DXnMf83m","https://ap.wps.com/l/cbCaiq70DXnMf83m","pdf",1902891,"English","# Foreword\n## Historical significance of Arthus' work\n## Philosophical preface and its origin\n## Value to students and relation to Claude Bernard\n## Publication, translation, and availability","[{\"question\":\"What is the main purpose of the monograph by Maurice Arthus, as described in the foreword?\",\"answer\":\"It records a direct experimental attack on the problem rather than serving as a review of current information. The work traces original observations related to repeated injections of horse serum in rabbits.\"},{\"question\":\"Why is Arthus’ preface described as especially fresh and appealing?\",\"answer\":\"The foreword links it to a personal circumstance: Arthus received a question from a young physician and chose to answer it by presenting his own experimental account along with an essay on the philosophy of scientific investigation.\"},{\"question\":\"How did the translation become available to readers, according to the foreword?\",\"answer\":\"A translation was contemplated but did not materialize until Henry E. Sigerist suggested the task to Dr. Sigerist. With his enthusiasm and kindness, the preface was made readily available, with publication by the Johns Hopkins Press in 1943.\"}]","MAURICE ARTHUS' PHILOSOPHY OF SCIENTIFIC INVESTIGATION - Preface & Foreword | PDF",1790627174,101]