[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-457949-en":3,"doc-seo-457949-105":31,"detail-sidebar-cat-0-en-105":99},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":21,"is_downloadable":21,"audit_status":21,"page_count":22,"language":23,"language_code":24,"site_id":25,"html_lang":24,"table_of_contents":26,"faqs":27,"seo_title":28,"seo_description":14,"update_tm":29,"read_time":30,"preview_page_count":4},457949,687197100911,"Himbo","https://ap-avatar.wpscdn.com/avatar/a000239b6f1da00475?x-image-process=image/resize,m_fixed,w_180,h_180&k=1785132997149421697",7,"Healthcare","Massive Ovarian Edema Successfully Treated Through Accurate Preoperative Diagnosis and Laparoscopic Conservative Surgery","Massive ovarian edema (MOE) is a rare benign condition causing marked ovarian enlargement through stromal fluid accumulation and can resemble an ovarian neoplasm. Accurate preoperative diagnosis helps avoid unnecessary oophorectomy, particularly in young women. A 26-year-old nulligravid woman presented with right lower abdominal pain; imaging suggested MOE and normal tumor markers. Laparoscopy showed 360-degree torsion; detorsion reduced size, wedge biopsy confirmed MOE, and follow-up showed complete normalization.","Review began 11/27/2025  \nReview ended 12/06/2025  \nPublished 12/08/2025  \n© Copyright 2025  \nYagi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nDOI: 10.7759/cureus.98762  \nOpen Access Case Report  \nMassive Ovarian Edema Successfully Treated Through Accurate Preoperative Diagnosis and Laparoscopic Conservative Surgery  \nMarina Yagi 1 , Takeshi Fukuda 1 , Takuma Wada 1, Makoto Yamauchi 1, Toshiyuki Sumi 1  \n1. Department of Obstetrics and Gynecology, Osaka Metropolitan University Graduate School of Medicine, Osaka, JPN Corresponding author: Takeshi Fukuda, [tfukuda@omu.ac.jp](tfukuda@omu.ac.jp)  \nAbstract  \nMassive ovarian edema (MOE) is a rare benign condition that causes marked ovarian enlargement due tostromal fluid accumulation and can mimic an ovarian neoplasm. Accurate preoperative diagnosis is essential to avoid unnecessary oophorectomy, especially in young women.  \nA 26-year-old nulligravid woman presented with right lower abdominal pain. Ultrasonography showed a markedly enlarged right ovary with peripheral follicles and mottled hypoechoic areas. MRI demonstrated an 85-mm enlarged ovary with high T2 signal intensity and multiple peripheral cysts, findings suggestive of MOE. Tumor markers were within normal limits. Based on characteristic imaging features and prior clinical experience, MOE was strongly suspected preoperatively. Laparoscopy revealed a markedly enlarged ovary with a 360-degree torsion. Following detorsion, the ovary decreased in size. A cortical incision revealed notumorous lesion, and serous fluid leaked from the stroma. A wedge biopsy was performed, and histopathology confirmed MOE. The postoperative course was uneventful, and follow-up ultrasonography one month later showed complete return of the ovary to normal size.  \nThis case illustrates the diagnostic value of characteristic ultrasonographic and MRI findings of MOE and highlights the importance of clinical experience in avoiding unnecessary oophorectomy and achieving fertility-preserving management.  \nCategories: Obstetrics/Gynecology, Radiology  \nKeywords: conservative surgery, fertility preservation, laparoscopy, massive ovarian edema, ovarian torsion  \nIntroduction  \nMassive ovarian edema (MOE) is a rare, tumor-like gynecological condition characterized by marked enlargement of the ovary due to the accumulation of edematous fluid within the ovarian stroma, first described by Kalstone [et al. in 1969](et al. in 1969) [1]. This condition predominantly affects adolescents and young women, with a mean reported age of approximately 20 years; however, both premenarcheal [2] and postmenopausal women [3] may also be affected. MOE is generally considered to result from partial or intermittent torsion of the ovarian pedicle, leading to impaired venous and lymphatic drainage while preserving arterial inflow [1] .  \nClinically and radiologically, MOE often mimics a solid ovarian neoplasm, creating a diagnostic challenge. Ultrasonography and computed tomography may show nonspecific ovarian enlargement, whereas magnetic resonance imaging has been reported to reveal characteristic findings such as peripheral displacement of follicles around a centrally edematous stroma-features that may assist in distinguishing this entity from true ovarian tumors [4,5] . Because MOE is a benign and potentially reversible condition, misdiagnosis may lead to unnecessary oophorectomy, resulting in avoidable loss of ovarian function. Fertility-preserving, conservative surgical management is therefore recommended whenever malignancy can be reasonably excluded.  \nAccurate preoperative recognition is essential, particularly in young women presenting with solid-appearing ovarian enlargement. The present report describes a case of MOE in a 26-year-old woman that was success","cbCaiuyPSz5J5cDw","https://ap.wps.com/l/cbCaiuyPSz5J5cDw","pdf",3773474,10,1,6,"English","en",105,"# Abstract\n# Introduction\n# Case Presentation\n## Imaging findings\n## How to cite this article\n## Figure 1\n## Figure 2","[{\"question\":\"What is massive ovarian edema (MOE) and why is it clinically important?\",\"answer\":\"MOE is a rare benign condition where the ovary enlarges due to edematous fluid in the stroma. It can mimic an ovarian neoplasm, so correct diagnosis is crucial to prevent unnecessary oophorectomy.\"},{\"question\":\"How was MOE suspected preoperatively in this case?\",\"answer\":\"Ultrasonography showed a markedly enlarged ovary with peripheral follicles and mottled hypoechoic areas, and MRI demonstrated an enlarged ovary with high T2 signal intensity and multiple peripheral cysts. Tumor markers were within normal limits.\"},{\"question\":\"What treatment was performed and what was the outcome?\",\"answer\":\"Laparoscopy revealed a markedly enlarged ovary with 360-degree torsion. After detorsion and wedge biopsy, histopathology confirmed MOE, and the postoperative course was uneventful with complete return to normal ovarian size by one month follow-up.\"}]","Massive Ovarian Edema Successfully Treated Through Accurate Preoperative Diagnosis and Laparoscopic Conservative Surgery | PDF",1790750943,15,{"code":4,"msg":32,"data":33},"ok",{"site_id":25,"language":24,"slug":34,"title":13,"keywords":35,"description":14,"schema_data":36,"social_meta":93,"head_meta":95,"extra_data":97,"updated_unix":98},"massive-ovarian-edema-successfully-treated-through-accurate-preoperative-diagnosis-and-laparoscopic-conservative-surgery","",{"@graph":37,"@context":92},[38,55,75],{"@type":39,"itemListElement":40},"BreadcrumbList",[41,45,49,52],{"item":42,"name":43,"@type":44,"position":21},"https://docshare.wps.com","Home","ListItem",{"item":46,"name":47,"@type":44,"position":48},"https://docshare.wps.com/document/","Document",2,{"item":50,"name":12,"@type":44,"position":51},"https://docshare.wps.com/document/healthcare/",3,{"item":53,"name":13,"@type":44,"position":54},"https://docshare.wps.com/document/massive-ovarian-edema-successfully-treated-through-accurate-preoperative-diagnosis-and-laparoscopic-conservative-surgery/457949/",4,{"url":53,"name":13,"@type":56,"image":57,"author":62,"headline":13,"publisher":64,"fileFormat":67,"inLanguage":24,"description":14,"dateModified":68,"datePublished":69,"encodingFormat":67,"isAccessibleForFree":70,"interactionStatistic":71},"DigitalDocument",{"url":58,"@type":59,"width":60,"height":61},"https://docshare.wps.com/thumbnails/massive-ovarian-edema-successfully-treated-through-accurate-preoperative-diagnosis-and-laparoscopic-conservative-surgery/457949.png","ImageObject",300,407,{"name":9,"@type":63},"Person",{"url":42,"name":65,"@type":66},"DocShare","Organization","application/pdf","2026-11-03","2026-09-30",true,{"@type":72,"interactionType":73,"userInteractionCount":20},"InteractionCounter",{"@type":74},"ViewAction",{"@type":76,"mainEntity":77},"FAQPage",[78,84,88],{"name":79,"@type":80,"acceptedAnswer":81},"What is massive ovarian edema (MOE) and why is it clinically important?","Question",{"text":82,"@type":83},"MOE is a rare benign condition where the ovary enlarges due to edematous fluid in the stroma. It can mimic an ovarian neoplasm, so correct diagnosis is crucial to prevent unnecessary oophorectomy.","Answer",{"name":85,"@type":80,"acceptedAnswer":86},"How was MOE suspected preoperatively in this case?",{"text":87,"@type":83},"Ultrasonography showed a markedly enlarged ovary with peripheral follicles and mottled hypoechoic areas, and MRI demonstrated an enlarged ovary with high T2 signal intensity and multiple peripheral cysts. Tumor markers were within normal limits.",{"name":89,"@type":80,"acceptedAnswer":90},"What treatment was performed and what was the outcome?",{"text":91,"@type":83},"Laparoscopy revealed a markedly enlarged ovary with 360-degree torsion. After detorsion and wedge biopsy, histopathology confirmed MOE, and the postoperative course was uneventful with complete return to normal ovarian size by one month follow-up.","https://schema.org",{"og:url":53,"og:type":94,"og:title":13,"og:site_name":65,"og:description":14},"article",{"robots":96,"canonical":53},"index,follow",{"doc_id":7,"site_id":25},1791086515,{"code":4,"msg":5,"data":100},[101,105,109,113,118,122,125,130,135,138,141],{"id":21,"doc_module":4,"doc_module_name":47,"category_name":102,"show_sort_weight":103,"slug":104},"Story & Novel",90,"story-novel",{"id":48,"doc_module":4,"doc_module_name":47,"category_name":106,"show_sort_weight":107,"slug":108},"Literature",80,"literature",{"id":54,"doc_module":4,"doc_module_name":47,"category_name":110,"show_sort_weight":111,"slug":112},"Exam",70,"exam",{"id":114,"doc_module":4,"doc_module_name":47,"category_name":115,"show_sort_weight":116,"slug":117},5,"Comic",60,"comic",{"id":22,"doc_module":4,"doc_module_name":47,"category_name":119,"show_sort_weight":120,"slug":121},"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":47,"category_name":12,"show_sort_weight":123,"slug":124},40,"healthcare",{"id":126,"doc_module":4,"doc_module_name":47,"category_name":127,"show_sort_weight":128,"slug":129},8,"Research & Report",30,"research-report",{"id":131,"doc_module":4,"doc_module_name":47,"category_name":132,"show_sort_weight":133,"slug":134},9,"Religion & Spirituality",20,"religion-spirituality",{"id":133,"doc_module":4,"doc_module_name":47,"category_name":136,"show_sort_weight":133,"slug":137},"World Cup","world-cup",{"id":20,"doc_module":4,"doc_module_name":47,"category_name":139,"show_sort_weight":20,"slug":140},"Lifestyle","lifestyle",{"id":142,"doc_module":4,"doc_module_name":47,"category_name":143,"show_sort_weight":114,"slug":144},19,"General","general"]