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Outcomes included en bloc, complete, and curative resection rates, local recurrence, adverse events, and procedure-related mortality. In 105 included lesions, en bloc resection reached 96.2%, complete resection 81.0%, and curative resection 64.8%, with adverse events totaling 5.7% (delayed bleeding 1.0%, perforation 1.9%, stricture 2.9%). Median follow-up was 18 months with local recurrence 3.8% and metachronous lesions 8.6%.",{"@graph":69,"@context":127},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/management-of-esophageal-neoplasms-by-endoscopic-submucosal-dissection-experience-over-100-consecutive-procedures/385217/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/management-of-esophageal-neoplasms-by-endoscopic-submucosal-dissection-experience-over-100-consecutive-procedures/385217.png","ImageObject",300,407,{"name":92,"@type":93},"Grenda","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-27","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",12,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119,123],{"name":110,"@type":111,"acceptedAnswer":112},"What was the main goal of this study on esophageal ESD?","Question",{"text":113,"@type":114},"To present clinical results of using ESD to manage superficial esophageal neoplasms in a Latin American center across over 100 consecutive cases.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"Which treatment outcomes were evaluated?",{"text":118,"@type":114},"En bloc, complete, and curative resection rates, local recurrence, adverse events, and procedure-related mortality.",{"name":120,"@type":111,"acceptedAnswer":121},"What were the key effectiveness and safety results?",{"text":122,"@type":114},"En bloc resection was 96.2% and complete resection 81.0%, with curative resection 64.8%. Adverse events occurred in 5.7%, including delayed bleeding (1.0%), perforation (1.9%), and stricture (2.9%).",{"name":124,"@type":111,"acceptedAnswer":125},"What follow-up findings were reported regarding recurrence?",{"text":126,"@type":114},"Local recurrence rate was 3.8% and metachronous lesion rate was 8.6%, with an average follow-up period of 29.7 months.","https://schema.org",{"og:url":83,"og:type":129,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":131,"canonical":83},"index,follow",{"doc_id":133,"site_id":62},385217,1790445863,{"code":4,"msg":5,"data":136},{"doc_id":133,"user_id":137,"nickname":92,"user_avatar":138,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":139,"file_id":140,"file_url":141,"file_type":142,"file_size":143,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":52,"language":144,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":145,"faqs":146,"seo_title":147,"seo_description":67,"update_tm":148,"read_time":149},7971474921005,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","ORIGINAL ARTICLE  \nClin Endosc 2023;56:613-622 [https://doi.org/10.5946/ce.2022.245](https://doi.org/10.5946/ce.2022.245)  \n[pISSN: 2234-2400](pISSN: 2234-2400) • eISSN: 2234-2443  \nOpen Access  \nManagement of esophageal neoplasms by endoscopic submucosal dissection: experience over 100 consecutive procedures  \nJosué Aliaga Ramos1,2,3, Yoshinori Morita4, Takashi Toyonaga4, Danilo Carvalho5, Moises Salgado Pedrosa6, Vitor N. Arantes7  \n1Department of Gastroenterology,“Jose Agurto Tello-Chosica” Hospital, Lima; 2Digestive Endoscopy Unit of San Pablo Clinic, Lima; 3Faculty of Medicine, Cayetano Heredia Peruvian University, Lima, Perú; 4Department of Gastroenterology, Kobe University International Clinical Cancer Reserch Center, Kobe, Japan; 5Endoscopy Unit, Alfa Institute of Gastroenterology, Belo Horizonte; 6Pathology Department, Alfa Institute of Gastroenterology, School of Medicine, Federal University of Minas Gerais, Laboratório CEAP, Belo Horizonte; 7Endoscopy Unit, Alfa Institute of Gastroenterology, School of Medicine, Federal University of Minas Gerais, Hospital Mater Dei Contorno, Belo Horizonte, Brazil  \nManagement of esophageal neoplasms by endoscopic submucosal dissection: experience over 􏚲􏚱􏚱 consecutive procedures  \n• Number of included lesions: 105  \n• Mean size: 33.8 mm (10−100 mm)  \n• Median follow-up period: 18 months  \n• En bloc resection rate: 96.2%  \n• Complete resection rate: 81.0%  \n• Curative resection rate: 64.8%  \n• Adverse events: 5.7%  \n- Delayed bleeding: 1.0%  \n- Perforation: 1.9%  \n- Stricture: 2.9%  \n• Local recurrence rate: 3.8%  \n• Metachronous lesion rate: 8.6%  \nESD performed by trained operators is feasible, safe, and clinically effective for managing superficial neoplastic lesions of the esophagus in LatinAmerica.  \nClin Endosc 􏚳􏚱􏚳􏚴; 􏚶􏚷: 􏚷􏚲􏚴‒􏚷􏚳􏚳  \nReceived: September 1, 2022 Revised: November 7, 2022  \nAccepted: November 14, 2022  \nCorrespondence: Vitor N. Arantes  \nEndoscopy Unit, Alfa Institute of Gastroenterology, School of Medicine, Federal University of Minas Gerais, Hospital Mater Dei Contorno, Belo Horizonte 30310690, Brazil  \n[E-mail:](E-mail: arantesvitor@ufmg.br)[ arantesvitor@ufmg.br](E-mail: arantesvitor@ufmg.br)  \n This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ([http://creativecommons.org/licenses/by-nc/4.0/](http://creativecommons.org/licenses/by-nc/4.0/)) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.  \nCopyright © 2023 Korean Society of Gastrointestinal Endoscopy 613  \nBackground/Aims: Endoscopic submucosal dissection (ESD) is currently considered the first-line treatment for the eradication of superficial neoplasms of the esophagus in Eastern countries. However, in the West, particularly in Latin America, the experience with esophageal ESD is still limited because of the high technical complexity required for its execution. This study aimed to present the results ofthe clinical application of ESD to manage superficial esophageal neoplasms in a Latin American center in over 100 consecutive cases.  \nMethods: This retrospective study included consecutive patients who underwent endoscopic ESD for superficial esophageal neoplasms between 2009 and 2022. The following clinical outcomes were assessed: en bloc, complete, and curative resection rates, local recurrence, adverse events, and procedure-related mortality.  \nResults: Esophageal ESD was performed mainly for squamous cell carcinoma (66.6%), high-grade intraepithelial neoplasia (17.1%), and adenocarcinoma (11.4%). En bloc and complete resection rates were 96.2% and 81.0%, respectively. The curative resection rate was 64.8%. Adverse events occurred in six cases (5.7%). Endoscopic follow-up was performed for an average period of 29.7 months. Conclusions: ESD performed by trained operators is feasible, safe, and clinically effective for managing superficial neoplastic lesi","cbCaifO8TsmBOg9F","https://ap.wps.com/l/cbCaifO8TsmBOg9F","pdf",3633414,"English","# Background/Aims\n# Methods\n## Patients\n# Results\n# Conclusions\n# Keywords","[{\"question\":\"What was the main goal of this study on esophageal ESD?\",\"answer\":\"To present clinical results of using ESD to manage superficial esophageal neoplasms in a Latin American center across over 100 consecutive cases.\"},{\"question\":\"Which treatment outcomes were evaluated?\",\"answer\":\"En bloc, complete, and curative resection rates, local recurrence, adverse events, and procedure-related mortality.\"},{\"question\":\"What were the key effectiveness and safety results?\",\"answer\":\"En bloc resection was 96.2% and complete resection 81.0%, with curative resection 64.8%. Adverse events occurred in 5.7%, including delayed bleeding (1.0%), perforation (1.9%), and stricture (2.9%).\"},{\"question\":\"What follow-up findings were reported regarding recurrence?\",\"answer\":\"Local recurrence rate was 3.8% and metachronous lesion rate was 8.6%, with an average follow-up period of 29.7 months.\"}]","Management of esophageal neoplasms by endoscopic submucosal dissection - experience over 100 consecutive procedures | PDF",1790267404,25]