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This article reports a 39-year-old woman admitted with progressive enlargement of an abdominal mass and provides clinical context including prior thoracic teratoma surgery and cesarean section history. The paper outlines the rarity, diagnostic criteria, and clinical considerations, and emphasizes multidisciplinary management and individualized therapy with attention to vigilant follow-up.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/malignant-transformation-associated-with-endometrioid-adenocarcinoma-of-abdominal-wall-endometriosis-case-report-and-literature-review/420418/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/malignant-transformation-associated-with-endometrioid-adenocarcinoma-of-abdominal-wall-endometriosis-case-report-and-literature-review/420418.png","ImageObject",300,407,{"name":92,"@type":93},"LangkahRina","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-06","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is abdominal wall endometriosis, and how rare is malignant transformation?","Question",{"text":113,"@type":114},"Abdominal wall endometriosis (AWE) involves endometriosis lesions within the abdominal wall and has an extremely low incidence. Malignant transformation of AWE is exceptionally rare and is mostly documented through case reports.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What was the clinical presentation in the reported case?",{"text":118,"@type":114},"A 39-year-old female was admitted for progressive enlargement of an abdominal mass over about four months. Her history included prior surgery for a left lung teratoma and a cesarean section, with no family history of malignancy.",{"name":120,"@type":111,"acceptedAnswer":121},"Why is a multidisciplinary approach important for AWE with suspected malignant transformation?",{"text":122,"@type":114},"The article stresses heightened vigilance for malignant transformation in AWE patients and suggests a multidisciplinary team (MDT) approach. 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This condition is one of the most common benign endometrioid proliferations, especially among premenopausal women. Although it is considered benign, endometriosis shares biological characteristics with malignant tumors, including invasion, implantation, metastasis, and recurrence. Abdominal wall endometriosis (AWE) refers to the presence of endometriosis lesions within the abdominal wall, with an extremely low incidence. Malignant transformation of AWE is exceptionally rare.\u003Cbr>Case Presentation: A 39-year-old female was admitted to the hospital on May 11, 2023, due to progressive enlargement of an abdominal mass noticed over a period of 4 months. To our knowledge, malignant transformation of abdominal wall endometriosis (AWE) is extremely rare in clinical practice, and cases of endometrioid adenocarcinoma arising from cesarean section-related AWE are even more scarce. Her medical history included surgery for a left lung teratoma 20 years ago and a cesarean section 6 years ago, with no family history of malignant tumor. This report presents a case of AWE subsequent to cesarean section, demonstrating a rare occurrence of malignant transformation into endometrioid adenocarcinoma.\u003Cbr>Conclusion: This article emphasizes the need for heightened vigilance regarding the possibility of malignant transformation in AWE patients and suggests a multidisciplinary team (MDT) approach and individualized treatment to improve clinical outcomes. A summary of the malignant transformation associated with endometrioid adenocarcinoma in cases of AWE has been provided to describe the Pathogenesis, Clinical Manifestation, Auxiliary Examination, Pathological Features, Treatment and Follow-up of this rare condition.\u003Cbr>Keywords: abdominal wall endometriosis, malignant transformation, endometrioid adenocarcinoma |\n| --- |\n| Introduction\u003Cbr>Endometriosis is defined as the presence of endometrial glands and stroma outside the uterine cavity.1 It affects approximately 176 million women worldwide, with an incidence rate of 10–15% among women of childbearing age.1 As a benign disease, endometriosis exhibits characteristics reminiscent of malignant tumors,2 and a small percentage (0.7% to 1%) of endometriosis patients have a risk of malignancy. In 1925, Sampson first described of malignant transformation of ectopic endometrial tissue and proposed three diagnostic criteria for the disease: (1) close association of endometriosis with the tumor; (2) histological consistency with endometrial origin; (3) absence of other primary tumor sites. Subsequently, in 1953, Scott introduced an additional diagnostic criterion: (4) morphologic demonstration of benign endometriosis contiguous with malignant tissue.2,3 However, the clinical application of these criteria has limitations, especially when dealing with small adjacent benign endometriosis lesions or those affected by adjacent malignant tissue |\n\nReceived: 6 October 2025  \nAccepted: 23 December 2025  \nPublished: 30 December 2025  \nInt","cbCaiisz4HjlfnSe","https://ap.wps.com/l/cbCaiisz4HjlfnSe","pdf",787752,"English","# Introduction\n## Case Presentation\n## Conclusion","[{\"question\":\"What is abdominal wall endometriosis, and how rare is malignant transformation?\",\"answer\":\"Abdominal wall endometriosis (AWE) involves endometriosis lesions within the abdominal wall and has an extremely low incidence. Malignant transformation of AWE is exceptionally rare and is mostly documented through case reports.\"},{\"question\":\"What was the clinical presentation in the reported case?\",\"answer\":\"A 39-year-old female was admitted for progressive enlargement of an abdominal mass over about four months. Her history included prior surgery for a left lung teratoma and a cesarean section, with no family history of malignancy.\"},{\"question\":\"Why is a multidisciplinary approach important for AWE with suspected malignant transformation?\",\"answer\":\"The article stresses heightened vigilance for malignant transformation in AWE patients and suggests a multidisciplinary team (MDT) approach. It also recommends individualized treatment planning to improve clinical outcomes.\"}]","Malignant Transformation Associated with Endometrioid Adenocarcinoma of Abdominal Wall Endometriosis - Case Report and Literature Review | PDF",1790620902,23]