[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-437644-105":59,"doc-detail-437644-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","making-future-udders-mammary-development-and-perinatal-programming-of-dairy-cattle","Making future udders - Mammary development and perinatal programming of dairy cattle","","The last 2 months before birth and the first 2 months after birth form a crucial developmental window in dairy cows, when mammary gland development is highly sensitive to environmental and nutritional influences. Evidence summarized in the review challenges the idea that major mammary growth starts only after weaning or around puberty, showing substantial early mammary parenchyma development during the perinatal period. Heat abatement and improved nutrition enhance parenchyma growth and support greater future milk productivity.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/making-future-udders-mammary-development-and-perinatal-programming-of-dairy-cattle/437644/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/making-future-udders-mammary-development-and-perinatal-programming-of-dairy-cattle/437644.png","ImageObject",300,407,{"name":92,"@type":93},"Kurz","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-06","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why is the perinatal period important for mammary development in dairy cattle?","Question",{"text":113,"@type":114},"The review states that the final 2 months of gestation and the first 2 months after birth are a critical window for mammary gland development. Mammary parenchymal growth during this period is highly sensitive to environmental and nutritional factors.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How does early-life management affect future milk production?",{"text":118,"@type":114},"Heat abatement and higher nutritional planes early in life increase mammary parenchyma growth. Proper perinatal management is described as essential to optimize lifetime milk yield and future lactational performance.",{"name":120,"@type":111,"acceptedAnswer":121},"What challenges the traditional view of mammary growth timing in dairy cows?",{"text":122,"@type":114},"The review reports evidence that significant mammary parenchyma development occurs during the perinatal period, not only after weaning or around puberty. It also describes pronounced allometric growth of the mammary parenchyma from birth to around 60 days.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},437644,1790812106,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":29,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},2336478945635,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","JDS Communications® 2025; 6:S42–S46  \n[https://doi.org/10.3168/jdsc.2025-0828](https://doi.org/10.3168/jdsc.2025-0828)[ ](https://doi.org/10.3168/jdsc.2025-0828)Invited Review Physiology  \nMaking future udders: Mammary development and perinatal programming of dairy cattle  \nJimena Laporta*  and Maverick C. Guenther   \nGraphical Abstract  \nSummary  \nThe last 2 months before birth and the first 2 months after birth represent a crucial window for organ development, including the mammary gland, in dairy cows. Traditionally, it was thought that allometric mammary growth began after weaning or around puberty. However, recent research indicates that significant early development of the mammary parenchyma occurs during the perinatal period and can influence a cow’s future milk production. This early growth is highly sensitive to environmental and nutritional factors. Heat stress abatement and higher nutritional planes in early life increase mammary parenchyma growth and improve future productivity. Proper management during the perinatal period is essential to optimize lifetime milk yield.  \nHighlights  \n• The perinatal period is a critical window for mammary parenchymal development.  \n• Early-life heat abatement and enhanced milk nutrition promote parenchyma growth.  \n• Environmental and nutritional factors can program future lactational performance.  \nDepartment of Animal and Dairy Sciences, University of Wisconsin–Madison, Madison, WI 53706. *[Corresponding author:](Corresponding author: jlaporta@wisc.edu)[ jlaporta@wisc.edu](Corresponding author: jlaporta@wisc.edu). © 2025, The Authors. Published by Elsevier Inc. on behalf of the American Dairy Science Association®. This is an open access article under the CC BY license ([https://](https://)[ ](https://)[creativecommons.org/licenses/by/4.0/](creativecommons.org/licenses/by/4.0/)). Received July 01, 2025. Accepted August 16, 2025.  \nThe list of standard abbreviations [for JDSC is available at](for JDSC is available at adsa.org/jdsc-abbreviations-25. Nonstandard abbreviations are available in the Notes)[ adsa.org/jdsc-abbreviations-25](for JDSC is available at adsa.org/jdsc-abbreviations-25. Nonstandard abbreviations are available in the Notes)[. Nonstandard abbreviations are available in the Notes](for JDSC is available at adsa.org/jdsc-abbreviations-25. Nonstandard abbreviations are available in the Notes).  \nJDS Communications® 2025; 6:S42–S46  \n[https://doi.org/10.3168/jdsc.2025-0828](https://doi.org/10.3168/jdsc.2025-0828)[ ](https://doi.org/10.3168/jdsc.2025-0828)Invited Review Physiology  \nMaking future udders: Mammary development and perinatal programming of dairy cattle  \nJimena Laporta*  and Maverick C. Guenther   \nAbstract: The perinatal period, described herein as the time spanning the final 2 mo of gestation through 2 mo postnatal, is a critical window of developmental plasticity for many organs in placental mammals, including the mammary gland (MG) . In dairy cattle, early-life MG development involves foundational morphogenic events that are highly sensitive to environmental and nutritional factors. Emerging evidence challenges the long-standing belief that substantial MG development begins after weaning and lasts until puberty, showing instead that preweaning mammary parenchymal (mPAR) growth is allometric and its degree of development can influence future lactational capacity. Overall BW typically doubles from birth to 60 d, whereas both whole udder weight and the mammary fat pad increase by ~2.2 to 3 times over the same period. In contrast, the mPAR exhibits pronounced allometric growth, expanding 15 to 35 times during this time. Early-life management strategies, such as heat abatement to maintain thermal homeostasis and enhanced nutrition through higher milk intake supporting greater average daily gain, further promote mPAR development and can positively influence future lactation performance of dairy cows. These findings underscore the importance of integrating dev","cbCaifPIBDePiZ4L","https://ap.wps.com/l/cbCaifPIBDePiZ4L","pdf",1261457,"English","# Graphical Abstract\n# Summary\n## Perinatal window for mammary development\n## Environmental and nutritional influences\n# Highlights\n## Critical timing for parenchymal development\n## Milk nutrition and heat abatement\n## Programming of future lactational performance\n# Abstract\n## Definition of the perinatal period\n## Allometric growth of mammary parenchyma\n## Management strategies and outcomes\n# Perinatal programming concept\n## Developmental plasticity and long-term outcomes\n# Adverse in utero conditions\n## Maternal nutrition restriction and hyperthermia","[{\"question\":\"Why is the perinatal period important for mammary development in dairy cattle?\",\"answer\":\"The review states that the final 2 months of gestation and the first 2 months after birth are a critical window for mammary gland development. Mammary parenchymal growth during this period is highly sensitive to environmental and nutritional factors.\"},{\"question\":\"How does early-life management affect future milk production?\",\"answer\":\"Heat abatement and higher nutritional planes early in life increase mammary parenchyma growth. Proper perinatal management is described as essential to optimize lifetime milk yield and future lactational performance.\"},{\"question\":\"What challenges the traditional view of mammary growth timing in dairy cows?\",\"answer\":\"The review reports evidence that significant mammary parenchyma development occurs during the perinatal period, not only after weaning or around puberty. It also describes pronounced allometric growth of the mammary parenchyma from birth to around 60 days.\"}]","Making future udders - Mammary development and perinatal programming of dairy cattle | PDF",1790682610,15]