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Twenty-two articles met inclusion criteria, with higher comparative incidence and poorer survival suggested across these populations.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/research-report/","Research & 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purpose of the scoping review?","Question",{"text":63,"@type":64},"To develop a deeper understanding of lung cancer diagnosis, incidence, mortality, and survival in First Nations, Inuit, and Métis peoples in Canada, addressing an identified literature gap.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How were studies selected for the review?",{"text":68,"@type":64},"A systematic search was conducted in bibliographic databases for studies published between January 2000 and March 2023, and articles were screened and assessed for relevance using the Population/Concept/Context (PCC) framework.",{"name":70,"@type":61,"acceptedAnswer":71},"What overall findings were suggested about lung cancer outcomes?",{"text":72,"@type":64},"The literature suggests higher incidence and mortality and poorer survival for First Nations, Inuit, and Métis peoples, with varying impact by sex, age, location, and other 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in Canada – a scoping review  \nJames Russell O’Gradya, Jannatul Ferdusb, Sayna Leylachiana, Yinka Bolarinwab, Joshua Wagameseb, Lisa K Ellisona, Connie Sieduleb, Ricardo Batistab and Amanda J Shepparda,c  \na Indigenous Cancer Care Unit, Ontario Health, Toronto, Ontario, Canada; bThe Akausivik Inuit Family Health Team, Ottawa, Ontario, Canada; cDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada  \nABSTRACT  \nLung cancer is one of the most commonly diagnosed cancers in Canada and a leading cause of cancer mortality. Lung cancer also affects First Nations, Inuit and Métis peoples significantly in Canada, which deserves further investigation as there is a literature gap on this topic. We sought to develop a deeper understanding of lung cancer diagnosis, incidence, mortality, and survival in First Nations, Inuit, and Métis peoples in Canada. A systematic search was conducted in bibliographic databases to identify relevant studies published between January 2000 and March 2023. Articles were screened and assessed for relevance using the Population/ Concept/ Context (PCC) framework. A total of 22 articles were included in the final analysis, of which 13 were Inuitspecific, 7 were First Nations-specific, and 2 were Métis-specific. The literature suggests that comparative incidence, mortality, and relative risk of lung cancer is higher and survival is poorer in First Nations, Inuit and Métis peoples. Lung cancer also has varying impact on these population depending on sex, age, location and other factors. This review illustrates that more comprehensive quantitative and qualitative lung cancer research is essential to further identify the structural causes for the high incidence of the disease.  \nARTICLE HISTORY  \nReceived 7 March 2024 Revised 9 July 2024 Accepted 15 July 2024  \nKEYWORDS  \nLung; cancer; First Nations; Inuit; Metis; Canada  \nIntroduction  \nLung cancer is the second most commonly diagnosed cancer in Canada. In 2021, an estimated 21,000 Canadians died of lung cancer, rendering it the leading cause of cancer death [1]. Likewise, lung cancer is a major cause of morbidity, where outcomes reportedly disproportionately affect First Nations, Inuit, and Métis peoples in Canada compared to non-Indigenous Canadians (NIC)  \n[2]. Many factors influence disparities in cancer outcomes, yet very few studies have identified statistical data in the three distinguished Indigenous populations of Canada and compiled them to assess disparities among Indigenous and non-Indigenous people. In this review, we seek to explore what is known from the existing literature about the impact of lung cancer on First Nations, Inuit, and Métis peoples in Canada.  \nBackground  \nFirst Nations, Inuit, and Métis are Indigenous Peoples in Canada. Evidence suggests that the health outcomes amongst these populations are significantly poorer than  \nthe country’s non-Indigenous population, especially cancer risk and mortality. Compared to the non-Indigenous population, First Nations, Inuit, and Métis are more at risk of developing cancer and other chronic diseases [3–5]. A report by Health Council of Canada, 2005, showed that lung cancer is the most commonly diagnosed cancer in Indigenous people in Canada. In Ontario alone, the lung cancer incidence rate is 19% and 48% higher in Indigenous men and women respectively compared to their non-Indigenous counterparts [6].  \nThe high lung cancer mortality rate in First Nations, Inuit, and Métis can largely be attributed to its high incidence and late-stage diagnoses [7–9] . The diagnosis of lung cancer begins with a computed tomography (CT) scan in combination with other confirmatory tests, followed by surgery, radiation, chemotherapy, and targeted therapy or variations of these treatments throughout different phases of the patient’s treatment plan [10] . A few provinces have launched organised ","cbCaimyYLNTqoi9K","https://ap.wps.com/l/cbCaimyYLNTqoi9K","pdf",326421,"English","# Abstract\n# Introduction\n# Background\n# Materials and methods","[{\"question\":\"What was the purpose of the scoping review?\",\"answer\":\"To develop a deeper understanding of lung cancer diagnosis, incidence, mortality, and survival in First Nations, Inuit, and Métis peoples in Canada, addressing an identified literature gap.\"},{\"question\":\"How were studies selected for the review?\",\"answer\":\"A systematic search was conducted in bibliographic databases for studies published between January 2000 and March 2023, and articles were screened and assessed for relevance using the Population/Concept/Context (PCC) framework.\"},{\"question\":\"What overall findings were suggested about lung cancer outcomes?\",\"answer\":\"The literature suggests higher incidence and mortality and poorer survival for First Nations, Inuit, and Métis peoples, with varying impact by sex, age, location, and other factors.\"}]","Lung cancer in First Nations, Inuit, and Métis peoples in Canada - a scoping review | PDF",1789979727,25]