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This study applies period analysis to quantify how gastric cancer treatment and outcomes at Nanfang Hospital, Southern Medical University changed over the past 15 years. Survival status for 3915 patients from 2008–2022 was evaluated using 5-year relative survival rates. Results show marked improvement in 5-year survival, especially from 2018–2022, with progress linked to standardized surgery, perioperative management, and immunotherapy.",{"@graph":69,"@context":126},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/long-term-relative-survival-of-patients-with-gastric-cancer-from-a-large-scale-cohort-a-period-analysis/332750/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/long-term-relative-survival-of-patients-with-gastric-cancer-from-a-large-scale-cohort-a-period-analysis/332750.png","ImageObject",300,407,{"name":92,"@type":93},"Quinn","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-05","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118,122],{"name":109,"@type":110,"acceptedAnswer":111},"What was the main purpose of the period analysis in this study?","Question",{"text":112,"@type":113},"To assess how gastric cancer treatment and outcomes at the center changed over the past 15 years using period analysis and 5-year relative survival rates.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which patient group and time range were analyzed?",{"text":117,"@type":113},"A cohort of 3915 gastric cancer patients from Nanfang Hospital was analyzed over 15 years, spanning 2008 to 2022.",{"name":119,"@type":110,"acceptedAnswer":120},"What were the key findings about 5-year relative survival?",{"text":121,"@type":113},"The center’s 5-year relative survival rate increased notably, reaching 71.4% from 2018 to 2022, with improvements across age groups and generally by tumor stage, including stage IV.",{"name":123,"@type":110,"acceptedAnswer":124},"What factors does the paper suggest explain the survival improvement?",{"text":125,"@type":113},"Improvement is attributed to standardized surgical techniques, perioperative management, and immunotherapy, supported by the study’s survival data.","https://schema.org",{"og:url":83,"og:type":128,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":130,"canonical":83},"index,follow",{"doc_id":132,"site_id":62},332750,1790825810,{"code":4,"msg":5,"data":135},{"doc_id":132,"user_id":136,"nickname":92,"user_avatar":137,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":138,"file_id":139,"file_url":140,"file_type":141,"file_size":142,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":143,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":144,"faqs":145,"seo_title":146,"seo_description":67,"update_tm":147,"read_time":148,"preview_page_count":4},962075114765,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Zhang et al. BMC Cancer (2024) 24:1420 [https://doi.org/10.1186/s12885-024-13141-5](https://doi.org/10.1186/s12885-024-13141-5)  \nBMC Cancer  \nRESEARCH Open Access  \nLong-term relative survival of patients  with gastric cancer from a large-scale cohort: a period-analysis  \nHengyi Zhang 1†, Weihao Yang 1†, Xin Tan 1, Wenjun He 1, Liying Zhao 1*, Hao Liu 1* and Guoxin Li2*  \nAbstract  \nBackground Gastric cancer poses a significant global health challenge. We aim to use period analysis to assess the changes in gastric cancer treatment at our center over the past 15 years. This study reflects the current state of gastric cancer treatment at our center and provides valuable data to support clinical advancements.  \nMethod We used period analysis to evaluate the survival status of 3915 patients with gastric cancer at Nanfang Hospital, Southern Medical University, over a 15-year period spaning from 2008 to 2022. The 5-year relative survival rates were analyzed.  \nResult Our findings indicate that the 5-year relative survival rate at our center from 2018 to 2022 is 71.4% . From 2018 to 2022, the 5-year relative survival rates for patients aged \u003C 40, 40–54, 55–69, and ≥ 70 reached 67. 5%, 73. 5%, 72. 0%, and 67 . 1%, respectively. For stage IV patients, the 5-year relative survival rate reached 29% in 2018–2022. For stage I-III patients, the 5-year relative survival rate reached 89 . 7% in 2018–2022 . The five-year relative survival rate for patients who underwent laparoscopic surgery at our center rose from 50. 3% in 2008–2012 to 71.4% in 2018–2022. Overall, there has been a notable increase in the 5-year relative survival rates, regardless of age, gender, region, or tumor stage. Conclusion Period analysis over the past 15 years shows significant improvement in the 5-year survival rate for gastric cancer at our center. This progress is due to standardized surgical techniques, perioperative management, and immunotherapy, providing robust data for evaluating the efficacy of recent treatments.  \nKeywords Gastric cancer, Period analysis, 5-year relative survival  \n†Hengyi Zhang and Weihao Yang contributed equally to this work.  \n*Correspondence: Liying Zhao  \nzlyblue1 [1@163.com](1@163.com)  \nHao Liu [liuhaofbi@163.com](liuhaofbi@163.com)[ ](liuhaofbi@163.com)Guoxin Li[gzliguoxin@163.com](gzliguoxin@163.com)  \n1Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China  \n2Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China  \nIntroduction  \nGastric cancer poses a serious threat to humanity, representing a major challenge to global health. According to the latest report from the Global Cancer Statistics Database, gastric cancer ranks fifth in global cancer incidence and fourth in cancer mortality, highlighting its substantial impact on public health [1]. Gastric cancer incidence is significantly higher in East Asia and Eastern Europe, while lower in North America, Northern Europe, and Africa. This global disparity is likely due to a combination of environmental, genetic, and infectious factors [2]. Although the incidence of gastric cancer has declined in  \n© The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is","cbCaicYdfFE7Sfdc","https://ap.wps.com/l/cbCaicYdfFE7Sfdc","pdf",2410907,"English","# Abstract\n## Background\n## Method\n## Result\n## Conclusion\n# Introduction\n## Global burden and trends\n## Factors influencing survival\n## Evidence for D1 vs D2 and laparoscopic approaches","[{\"question\":\"What was the main purpose of the period analysis in this study?\",\"answer\":\"To assess how gastric cancer treatment and outcomes at the center changed over the past 15 years using period analysis and 5-year relative survival rates.\"},{\"question\":\"Which patient group and time range were analyzed?\",\"answer\":\"A cohort of 3915 gastric cancer patients from Nanfang Hospital was analyzed over 15 years, spanning 2008 to 2022.\"},{\"question\":\"What were the key findings about 5-year relative survival?\",\"answer\":\"The center’s 5-year relative survival rate increased notably, reaching 71.4% from 2018 to 2022, with improvements across age groups and generally by tumor stage, including stage IV.\"},{\"question\":\"What factors does the paper suggest explain the survival improvement?\",\"answer\":\"Improvement is attributed to standardized surgical techniques, perioperative management, and immunotherapy, supported by the study’s survival data.\"}]","Long-term relative survival of patients with gastric cancer from a large-scale cohort: a period-analysis | PDF",1789999378,23]