[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-332243-105":59,"doc-detail-332243-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","long-term-cardiovascular-risk-reduction-after-gastric-cancer-surgery-a-nationwide-cohort-study","Long-term cardiovascular risk reduction after gastric cancer surgery - a nationwide cohort study","","Retrospective nationwide cohort evidence evaluates how gastrectomy versus endoscopic resection affects long-term cardiovascular outcomes after gastric cancer treatment. The study compares patients undergoing gastrectomy, patients undergoing endoscopic resection, and matched controls, tracking major adverse cardiovascular events (MACE) across follow-up periods. Results show a statistically reduced MACE risk after gastrectomy, while endoscopic resection does not differ significantly from general population risk, informing post-treatment cardiovascular risk management.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/long-term-cardiovascular-risk-reduction-after-gastric-cancer-surgery-a-nationwide-cohort-study/332243/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/long-term-cardiovascular-risk-reduction-after-gastric-cancer-surgery-a-nationwide-cohort-study/332243.png","ImageObject",300,407,{"name":92,"@type":93},"Noah","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-23","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What clinical question does the study address?","Question",{"text":112,"@type":113},"Whether gastrectomy or endoscopic resection for gastric cancer reduces long-term cardiovascular events compared with the general population.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the study designed and who were the participants?",{"text":117,"@type":113},"A retrospective nationwide cohort study included patients undergoing gastrectomy, patients undergoing endoscopic resection, and matched controls between 2004 and 2013.",{"name":119,"@type":110,"acceptedAnswer":120},"What were the main findings for MACE risk after different treatments?",{"text":121,"@type":113},"Gastrectomy patients had a significantly lower MACE risk than controls, while endoscopic resection patients did not show a significant difference versus controls.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},332243,1790143568,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},8796095462418,"https://ap-avatar.wpscdn.com/avatar/80000253c1241d02b47?x-image-process=image/resize,m_fixed,w_180,h_180&k=1778826106357471780","’Retrospective Cohort Study  \nLong-term cardiovascular risk reduction after gastric cancer surgery: a nationwide cohort study  \nYeongkeun Kwon, MD, PhDa,b , Dohyang Kim, MSc , Sangwoo Kimd , Jane Ha, MDf, Jinseub Hwang, PhDc , Sungsoo Park, MD, PhDa,b,* , Jin-Won Kwon, MPH, PhDe,*  \nBackground: Gastrectomy for gastric cancer is associated with postoperative changes in cardiovascular risk factors, however, the impact of gastrectomy on cardiovascular events remains unclear. The authors assessed the incidence of cardiovascular events between patients undergoing gastrectomy or endoscopic resection for gastric cancer, and the general population.  \nMaterials and methods: This retrospective nationwide cohort study included patients with gastric cancer undergoing gastrectomy (n = 37 698), endoscopic resection (n = 2773), and matched control population (n = 161 887) between 2004 and 2013 . The authors included patients without a history of cancer other than gastric cancer, myocardial infarction, or ischemic stroke. The primary outcome was the incidence of major adverse cardiovascular events (MACE) such as acute myocardial infarction, revascularization, or acute ischemic stroke, in patients with gastric cancer.  \nResults: Among patients who underwent gastrectomy for gastric cancer, 2 .9%(4 .69 per 1000 person-years) developed novel MACE within the 1-year follow-up period. The gastrectomy group demonstrated a significantly decreased risk for MACE than the control population [hazard ratio (HR), 0 .65; 95% CI: 0 .61–0.69; P \u003C 0.001) . Among the patients undergoing endoscopic resection for gastric cancer, 5 .4%(8 .21 per 1000 person-years) developed novel MACE within the 7-year follow-up period. The risk for MACE in the endoscopic resection group was not significantly different from the control population.  \nConclusion: Patients with gastric cancer who have undergone gastrectomy exhibit a reduced risk of cardiovascular diseases in comparison to the general population. In contrast, the risk for cardiovascular diseases in patients with gastric cancer who underwent endoscopic resection did not demonstrate a significant difference in cardiovascular risk in comparison to the general population. Keywords: cardiovascular risk, endoscopic resection, gastrectomy, gastric cancer  \nIntroduction  \nPatients with cancer have a 20-fold increased risk of cardiovascular disease, which is the leading cause of noncancer mortality among patients with cancer[1] . The increase in cardiovascular disease in patients with cancer can be attributed to both the cancer itself and the cancer treatment modality, which can be damaging to cardiovascular health[2] . This is of particular concern in gastric cancer, for which gastrectomy is the gold standard treatment. Given that gastrectomy is associated with postoperative weight loss and changes in the natural progression of  \ncomorbidities such as type 2 diabetes, hypertension, and dyslipidemia, both commonly known risk factors for cardiovascular disease[3–6] . Considering that the management of cardiovascular disease in patients with gastric cancer is closely related to both the survival rate and quality of life of the patient[2], assessing the risk of cardiovascular disease after gastrectomy is critical.  \nDepending on the lesion stage, the primary treatment modalities for gastric cancer are gastrectomy and endoscopic resection, both of which alter cardiovascular risk factors differently. In addition to lesion removal, gastric cancer surgery alters  \naDivision ofForegut Surgery, Korea University College of Medicine, bCenter for Obesity and Metabolic Diseases, Korea University Anam Hospital, Seoul, cDepartment of Statistics, Daegu University, Gyeongbuk, dDepartment of Medicine, Korea University College of Medicine, Seoul, eBK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, South Korea and fClin","cbCaimY9qdlpFeau","https://ap.wps.com/l/cbCaimY9qdlpFeau","pdf",719455,"English","# Background\n# Materials and methods\n# Results\n# Conclusion\n# Introduction","[{\"question\":\"What clinical question does the study address?\",\"answer\":\"Whether gastrectomy or endoscopic resection for gastric cancer reduces long-term cardiovascular events compared with the general population.\"},{\"question\":\"How was the study designed and who were the participants?\",\"answer\":\"A retrospective nationwide cohort study included patients undergoing gastrectomy, patients undergoing endoscopic resection, and matched controls between 2004 and 2013.\"},{\"question\":\"What were the main findings for MACE risk after different treatments?\",\"answer\":\"Gastrectomy patients had a significantly lower MACE risk than controls, while endoscopic resection patients did not show a significant difference versus controls.\"}]","Long-term cardiovascular risk reduction after gastric cancer surgery - a nationwide cohort study | PDF",1789997499,23]