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Poor outcomes are linked to limited drug specificity, resistance, and toxic side effects in healthy tissues. Nanotechnology supports targeted delivery by transporting anticancer agents and targeting ligands to tumors. Liposomes can carry therapeutic and imaging payloads for image-guided treatment and monitoring. This review summarizes liposome-based theranostics across cancer types, including photothermal/photodynamic approaches and imaging modalities.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/liposomes-for-cancer-theranostics/385275/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/liposomes-for-cancer-theranostics/385275.png","ImageObject",300,407,{"name":92,"@type":93},"4398046744996","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-04","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",12,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why do conventional cancer treatments often show poor responses?","Question",{"text":113,"@type":114},"Limited drug specificity, drug resistance, and toxic side effects in healthy tissues reduce effectiveness and contribute to poor response rates across different cancers.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How do liposomes support cancer theranostics?",{"text":118,"@type":114},"Liposomes load diverse therapy agents (e.g., drugs, photosensitizers, genetic material) and imaging agents (e.g., fluorophores, radioisotopes, MRI contrast), enabling treatment delivery and progress monitoring.",{"name":120,"@type":111,"acceptedAnswer":121},"What kinds of cancer therapies and imaging approaches are discussed?",{"text":122,"@type":114},"The review covers nanoparticle-based therapies, including photothermal and photodynamic treatments, and discusses imaging modalities used across different cancer types for image-guided therapy.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},385275,1790684860,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":66,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":41,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},4398046744996,"pharmaceutics  \nReview  \nLiposomes for Cancer Theranostics  \nDonald A. Fernandes   \nCitation: Fernandes, D.A. Liposomes for Cancer Theranostics. Pharmaceutics 2023, 15, 2448. [https://doi.org/](https://doi.org/)[ ](https://doi.org/)[10.3390/pharmaceutics15102448](10.3390/pharmaceutics15102448)  \nAcademic Editors: Nejat Düzgüne¸sand Patrick J. Sinko  \nReceived: 4 August 2023  \nRevised: 16 September 2023  \nAccepted: 28 September 2023  \nPublished: 11 October 2023  \nCopyright: © 2023 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ([https://](https://)[ ](https://)[creativecommons.org/licenses/by/](creativecommons.org/licenses/by/)[ ](creativecommons.org/licenses/by/)[4.0/](4.0/)) .  \nIndependent Researcher, Toronto, ON, Canada; [dfe.anthony@gmail.com](dfe.anthony@gmail.com)  \nAbstract: Cancer is one of the most well-studied diseases and there have been signiﬁcant advancements over the last few decades in understanding its molecular and cellular mechanisms. Although the current treatments (e.g., chemotherapy, radiotherapy, gene therapy and immunotherapy) have provided complete cancer remission for many patients, cancer still remains one of the most common causes of death in the world. The main reasons for the poor response rates for different cancers include the lack of drug speciﬁcity, drug resistance and toxic side effects (i.e., in healthy tissues) . For addressing the limitations of conventional cancer treatments, nanotechnology has shown to be an important ﬁeld for constructing different nanoparticles for destroying cancer cells. Due to their size (i.e., less than 1 􀀖m), nanoparticles can deliver signiﬁcant amounts of cancer drugs to tumors and are able to carry moieties (e.g., folate, peptides) for targeting speciﬁc types of cancer cells (i.e., through receptor-mediated endocytosis) . Liposomes, composed of phospholipids and an interior aqueous core, can be used as specialized delivery vehicles as they can load different types of cancer therapy agents (e.g., drugs, photosensitizers, genetic material) . In addition, the ability to load imaging agents (e.g., ﬂuorophores, radioisotopes, MRI contrast media) enable these nanoparticles to be used for monitoring the progress of treatment. This review examines a wide variety of different liposomes for cancer theranostics, with the different available treatments (e.g., photothermal, photodynamic) and imaging modalities discussed for different cancers.  \nKeywords: theranostics; nanoparticles; therapy; imaging; image-guided therapy  \n1. Introduction  \nNanomaterials have shown to be effective systems for a wide variety of biomedical applications, and have been used for treatment [1], delivery of therapeutics [2] and bio-imaging [3] . Signiﬁcant developments have arisen in nanotechnology, focusing on nanoparticles for both imaging and therapy, referred to as theranostics [4–7] . Nanoparticles are advantageous due to their physical and chemical properties, enabling them to be used for tumor monitoring and treatment. Materials such as gold nanoparticles [8,9], quantum dots [10,11], magnetic nanoparticles [12,13], upconversion nanoparticles [14,15], nanoemulsions [16–18], nanogels [19,20], micro/nano-bubbles [21–23], carbon nanoparticles [24,25], polymeric nanoparticles [26,27] and micelles [28,29] have all successfully been used for the diagnosis and treatment of cancer. Liposomes are unique nanoparticles that have been used for cancer theranostics, due to their ability to load both hydrophobic (i.e., in their lipophilic shell) and hydrophilic therapeutic and imaging agents (i.e., in the aqueous core) . The advantages of liposomes include the high loading efﬁciency of agents, high stability in biological conditions and controllable release kinetics due to stimuli responsiveness and biocompatibility, providing better pharmacokinetics and biodistribution of ","cbCaihuNZmJkMCtw","https://ap.wps.com/l/cbCaihuNZmJkMCtw","pdf",5738190,"English","# Introduction\n# Common Cancer Therapies\n## Advantages and disadvantages of cancer therapies\n# Liposome-based delivery for theranostics\n# Imaging modalities and treatment monitoring\n# Conclusions","[{\"question\":\"Why do conventional cancer treatments often show poor responses?\",\"answer\":\"Limited drug specificity, drug resistance, and toxic side effects in healthy tissues reduce effectiveness and contribute to poor response rates across different cancers.\"},{\"question\":\"How do liposomes support cancer theranostics?\",\"answer\":\"Liposomes load diverse therapy agents (e.g., drugs, photosensitizers, genetic material) and imaging agents (e.g., fluorophores, radioisotopes, MRI contrast), enabling treatment delivery and progress monitoring.\"},{\"question\":\"What kinds of cancer therapies and imaging approaches are discussed?\",\"answer\":\"The review covers nanoparticle-based therapies, including photothermal and photodynamic treatments, and discusses imaging modalities used across different cancer types for image-guided therapy.\"}]","Liposomes for Cancer Theranostics | PDF",1790267695,76]