[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-27475-en":3,"doc-seo-27475-105":27,"detail-sidebar-cat-0-en-105":69},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":4,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":20,"language":21,"language_code":22,"site_id":23,"html_lang":22,"table_of_contents":15,"faqs":15,"seo_title":24,"seo_description":14,"update_tm":25,"read_time":26},27475,687197100911,"Himbo","https://ap-avatar.wpscdn.com/avatar/a000239b6f1da00475?x-image-process=image/resize,m_fixed,w_180,h_180&k=1785132997149421697",7,"Healthcare","Lipopeptides and Other Anti-infective Drugs","This document provides a detailed overview of specific anti-infective drugs, focusing on their mechanisms of action, indications, and contraindications. It categorizes drugs based on their impact on bacterial protein synthesis, introducing lipopeptides, oxazolidinones, and spectinomycin as key subjects. Daptomycin, a cyclic lipopeptide, is highlighted for its use in treating complicated skin and skin structure bacterial infections and Staphylococcus aureus infections of the blood. Linezolid, the first in the oxazolidinone class, is indicated for vancomycin-resistant Enterococcus faecium (VREF), healthcare- and community-acquired pneumonias, and skin and skin structure infections. Spectinomycin, related to aminoglycosides, is prescribed for gonorrhea in patients allergic to penicillin or cephalosporins. Quinupristin/dalfopristin, a bacteriostatic agent, is also used for VREF infections. Contraindications include known hypersensitivity to the drugs, and specific warnings are given for Linezolid concerning PKU and pregnancy. Daptomycin, spectinomycin, and quinupristin/dalfopristin are listed as pregnancy category B, with precautions during pregnancy and lactation. A critical note is made regarding Quinupristin/dalfopristin's irritant properties to veins, requiring flushing with 5% dextrose in water (D5W) after peripheral infusion due to incompatibility with saline or heparin. The document adheres to strict reporting standards for medical information, emphasizing drug interactions and patient safety protocols within the nursing and healthcare context.","","cbCaijzDNGM33CYL","https://ap.wps.com/l/cbCaijzDNGM33CYL","pdf",605790,1,"English","en",105,"Lipopeptides and Other Anti-infective Drugs | PDF",1778275142,3,{"code":4,"msg":28,"data":29},"ok",{"site_id":23,"language":22,"slug":30,"title":13,"keywords":15,"description":14,"schema_data":31,"social_meta":64,"head_meta":66,"extra_data":68,"updated_unix":25},"lipopeptides-and-other-anti-infective-drugs",{"@graph":32,"@context":63},[33,49],{"@type":34,"itemListElement":35},"BreadcrumbList",[36,40,44,46],{"item":37,"name":38,"@type":39,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":41,"name":42,"@type":39,"position":43},"https://docshare.wps.com/document/","Document",2,{"item":45,"name":12,"@type":39,"position":26},"https://docshare.wps.com/document/healthcare/",{"item":47,"name":13,"@type":39,"position":48},"https://docshare.wps.com/document/lipopeptides-and-other-anti-infective-drugs/27475",4,{"url":47,"name":13,"@type":50,"author":51,"headline":13,"publisher":53,"fileFormat":56,"description":14,"dateModified":57,"datePublished":57,"encodingFormat":56,"isAccessibleForFree":58,"interactionStatistic":59},"DigitalDocument",{"name":9,"@type":52},"Person",{"url":37,"name":54,"@type":55},"DocShare","Organization","application/pdf","2026-05-08",true,{"@type":60,"interactionType":61,"userInteractionCount":4},"InteractionCounter",{"@type":62},"ViewAction","https://schema.org",{"og:url":47,"og:type":65,"og:title":13,"og:site_name":54,"og:description":14},"article",{"robots":67,"canonical":47},"index,follow",{"doc_id":7,"site_id":23},{"code":4,"msg":5,"data":70},[71,75,79,83,88,93,96,101,106,109,113],{"id":20,"doc_module":4,"doc_module_name":42,"category_name":72,"show_sort_weight":73,"slug":74},"Story & Novel",90,"story-novel",{"id":43,"doc_module":4,"doc_module_name":42,"category_name":76,"show_sort_weight":77,"slug":78},"Literature",80,"literature",{"id":48,"doc_module":4,"doc_module_name":42,"category_name":80,"show_sort_weight":81,"slug":82},"Exam",70,"exam",{"id":84,"doc_module":4,"doc_module_name":42,"category_name":85,"show_sort_weight":86,"slug":87},5,"Comic",60,"comic",{"id":89,"doc_module":4,"doc_module_name":42,"category_name":90,"show_sort_weight":91,"slug":92},6,"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":42,"category_name":12,"show_sort_weight":94,"slug":95},40,"healthcare",{"id":97,"doc_module":4,"doc_module_name":42,"category_name":98,"show_sort_weight":99,"slug":100},8,"Research & Report",30,"research-report",{"id":102,"doc_module":4,"doc_module_name":42,"category_name":103,"show_sort_weight":104,"slug":105},9,"Religion & Spirituality",20,"religion-spirituality",{"id":104,"doc_module":4,"doc_module_name":42,"category_name":107,"show_sort_weight":104,"slug":108},"World Cup","world-cup",{"id":110,"doc_module":4,"doc_module_name":42,"category_name":111,"show_sort_weight":110,"slug":112},10,"Lifestyle","lifestyle",{"id":114,"doc_module":4,"doc_module_name":42,"category_name":115,"show_sort_weight":84,"slug":116},19,"General","general"]