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I. C. testing","","Liofilchem -Direct M.I.C. testing presents a rapid workflow for microbiology products MTS, designed to deliver accurate antimicrobial susceptibility results for critical specimens. It targets Intensive Care Unit needs by supporting precise and fast AST, providing quantitative M.I.C. values for PK/PD optimization, reducing resistance selection, and enabling de-escalation. 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It also supports reducing resistance selection and guides therapy de-escalation.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How does direct MTS usage compare with broth microdilution in time to results?",{"text":117,"@type":113},"Direct MTS delivers results in less than 24 hours, while broth microdilution delivers results in 48–72 hours.",{"name":119,"@type":110,"acceptedAnswer":120},"What recommendations apply when reporting and validating direct M.I.C. results?",{"text":121,"@type":113},"Direct M.I.C. must be reported as “preliminary.” Results should be confirmed using the standard usage of MTS, and data should be collected to validate direct M.I.C. from the specimen versus standard M.I.C. from pure colony.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},505952,1791345392,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},962090894170,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","® LIOFILCHEM  \nDIAGNOSTICI  \nMicrobiology products MTS  \nDIRECT M.I.C.TESTING  \nUsage of Lioﬁlchem® MIC Test Strip (MTS) with critical specimens  \nLioﬁlchem® -Direct M. I. C. testing © 2012  \nLioﬁlchem® and the Lioﬁlchem company logo are registered trademarks of LIOFILCHEM s. r. l.  \n® LIOFILCHEM  \nDIAGNOSTICI  \nMicrobiology products MTS  \nMajor needs in the Intensive Care Units  \n• broaden the alternatives in therapy and outcome  \n• accurate and rapid AST results  \n• provide M.I.C. for PK/PD to optimise choice and dosage  \n• reduce resistance selection  \n• guide use of agent with high break-point M.I.C. quotient  \n• De-escalation of therapy  \nLioﬁlchem® -Direct M. I. C. testing © 2012  \nLioﬁlchem® and the Lioﬁlchem company logo are registered trademarks of LIOFILCHEM s. r. l.  \n® LIOFILCHEM  \nDIAGNOSTICI  \nMicrobiology products MTS  \nBeneﬁts of direct usage of MTS  \n• direct MTS delivers results in \u003C 24 h.  \n• Broth microdilution delivers results in 48-72 h.  \n• MTS provides accurate, quantitative, real M.I.C. for  \n-optimizing agent selection  \n-allowing dosage adjustment  \n-dosing properly  \n-minitoring the resistance during treatment  \nLioﬁlchem® -Direct M. I. C. testing © 2012  \nLioﬁlchem® and the Lioﬁlchem company logo are registered trademarks of LIOFILCHEM s. r. l.  \n® LIOFILCHEM  \nDIAGNOSTICI  \nMicrobiology products  \nMTS  \nBlood culture in the Intensive Care Unit  \n\n| positive bottle 0 h | agar plate 24 h | reading 48 h |\n| --- | --- | --- |\n| | | |\n| Gram stain | Presumptive ID | ID, AST |\n\nLioﬁlchem® -Direct M. I. C. testing © 2012  \nLioﬁlchem® and the Lioﬁlchem company logo are registered trademarks of LIOFILCHEM s. r. l.  \n® LIOFILCHEM  \nDIAGNOSTICI  \nMicrobiology products MTS  \nRespiratory specimens  \nVentilator-Associated Penumoniae (VAP)  \n\n| positive bottle 0 h | agar plate 24 h | isolates 48 h | reading results 72 h |\n| --- | --- | --- | --- |\n| | |  | |\n| Gram stain | Presumptive ID |  | ID, AST |\n\nLioﬁlchem® -Direct M. I. C. testing © 2012  \nLioﬁlchem® and the Lioﬁlchem company logo are registered trademarks of LIOFILCHEM s. r. l.  \n® LIOFILCHEM  \nDIAGNOSTICI  \nMicrobiology products MTS  \nMTS beneﬁts  \n• inoculum tolerance  \n• stable gradient  \n• valid for a large variety of microorganisms  \n• wide M.I.C. range  \n• over 100 antimicrobial agents  \n• accurate M.I.C. determination  \nLioﬁlchem® -Direct M. I. C. testing © 2012  \nLioﬁlchem® and the Lioﬁlchem company logo are registered trademarks of LIOFILCHEM s. r. l.  \n® LIOFILCHEM  \nDIAGNOSTICI  \nMicrobiology products MTS  \nInoculum tolerance  \n\n| M.I.C. |  |  |  |  |\n| --- | --- | --- | --- | --- |\n|  |  |  |  |  |\n|  | E. coli ATCC® 25922 Gentamicin\u003Cbr>107 CFU | E. coli ATCC® 25922 Gentamicin\u003Cbr>105 CFU | E. coli ATCC® 25922 Gentamicin\u003Cbr>103 CFU |  |\n\nLioﬁlchem® -Direct M. I. C. testing © 2012  \nLioﬁlchem® and the Lioﬁlchem company logo are registered trademarks of LIOFILCHEM s. r. l.  \n® LIOFILCHEM  \nDIAGNOSTICI  \nMicrobiology products MTS  \nDirect M.I.C. testing  \n• positive blood culture: Gram+ & Gram-aerobes, pneummococci, anaerobes, yeasts .  \n• cystic ﬁbrosis: sputum.  \n• VAP: bronchial aspirates, BAL, etc .  \n• meningitis: CSF.  \n• Urosepsis, ICU, etc.: urine .  \nLioﬁlchem® -Direct M. I. C. testing © 2012  \nLioﬁlchem® and the Lioﬁlchem company logo are registered trademarks of LIOFILCHEM s. r. l.  \n® LIOFILCHEM  \nDIAGNOSTICI  \nMicrobiology products MTS  \nDirect MTS method  \n• Gram stain: microscopical examination.  \n• inoculate the proper agar medium.  \n• apply MTS.  \n• incubate in the proper atmosphere .  \n• read the plates after 8-12-24 hours, or longer.  \nLioﬁlchem® -Direct M. I. C. testing © 2012  \nLioﬁlchem® and the Lioﬁlchem company logo are registered trademarks of LIOFILCHEM s. r. l.  \n® LIOFILCHEM  \nDIAGNOSTICI  \nMicrobiology products MTS  \nRecommendations  \n• direct M.I.C. must be reported as “preliminary”.  \n• conﬁrm the results of direct M.I.C. with the M.I.C. obtained by the standard usage of MTS.  \n• collect data for validating the dir","cbCairyiKQg9xEQN","https://ap.wps.com/l/cbCairyiKQg9xEQN","pdf",4095747,17,"English","# Major needs in the Intensive Care Units\n## Beneﬁts of direct usage of MTS\n## Blood culture in the Intensive Care Unit\n## Respiratory specimens (VAP)\n## MTS beneﬁts\n## Inoculum tolerance\n## Direct M.I.C. testing\n## Direct MTS method\n## Recommendations","[{\"question\":\"What are the main Intensive Care Unit needs addressed by Direct M.I.C. testing?\",\"answer\":\"It broadens therapy alternatives and improves outcomes, delivers accurate and rapid AST results, and provides quantitative M.I.C. values for PK/PD-driven choice and dosage optimization. It also supports reducing resistance selection and guides therapy de-escalation.\"},{\"question\":\"How does direct MTS usage compare with broth microdilution in time to results?\",\"answer\":\"Direct MTS delivers results in less than 24 hours, while broth microdilution delivers results in 48–72 hours.\"},{\"question\":\"What recommendations apply when reporting and validating direct M.I.C. results?\",\"answer\":\"Direct M.I.C. must be reported as “preliminary.” Results should be confirmed using the standard usage of MTS, and data should be collected to validate direct M.I.C. from the specimen versus standard M.I.C. from pure colony.\"}]","Liofilchem -Direct M. I. C. testing | PDF",1791156151,43]