[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-27819-en":3,"doc-seo-27819-105":27,"detail-sidebar-cat-0-en-105":69},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":4,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":20,"language":21,"language_code":22,"site_id":23,"html_lang":22,"table_of_contents":15,"faqs":15,"seo_title":24,"seo_description":14,"update_tm":25,"read_time":26},27819,34359740700684,"Finn","https://ap-avatar.wpscdn.com/avatar/1f400023980c374ae676?_k=1777273430885731487",7,"Healthcare","Lincosamides","This document provides a detailed overview of Lincosamides, an important class of anti-infective antibiotics. It explains their mechanism of action, which is the inhibition of protein synthesis in susceptible bacteria, ultimately leading to cell death by disrupting the functional ability of ribosomes. The indications for using lincosamides are discussed, highlighting their use in treating serious infections caused by a range of gram-negative and gram-positive microorganisms, often in conjunction with other antibiotics. Crucially, the document emphasizes the importance of evaluating culture and sensitivity test results before administering any antibiotic and stresses the need for patients to complete the entire prescribed course of treatment, even if symptoms improve, to prevent the recurrence of infection. The effectiveness of the treatment should be monitored by observing temperature and vital signs, and by evaluating lab results for decreasing white blood cell counts. Potential side effects are enumerated, including abdominal pain, esophagitis, nausea, vomiting, diarrhea, skin rash, blood dyscrasias, and pseudomembranous colitis. Contraindications are also listed, such as hypersensitivity to lincosamides, concomitant use of cisapride or pimozide, and use with minor bacterial or viral infections. Finally, the document outlines significant drug interactions, specifically with kaolin- or aluminum-based antacids, which decrease absorption, and with neuromuscular blocking drugs, which can potentiate their action and lead to severe respiratory depression. It also notes that food impairs the absorption of lincomycin, necessitating specific timing for administration, while clindamycin can be taken with food.","","cbCaiuiYhfGC29NX","https://ap.wps.com/l/cbCaiuiYhfGC29NX","pdf",596854,1,"English","en",105,"Lincosamides | PDF",1778276542,3,{"code":4,"msg":28,"data":29},"ok",{"site_id":23,"language":22,"slug":30,"title":13,"keywords":15,"description":14,"schema_data":31,"social_meta":64,"head_meta":66,"extra_data":68,"updated_unix":25},"lincosamides",{"@graph":32,"@context":63},[33,49],{"@type":34,"itemListElement":35},"BreadcrumbList",[36,40,44,46],{"item":37,"name":38,"@type":39,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":41,"name":42,"@type":39,"position":43},"https://docshare.wps.com/document/","Document",2,{"item":45,"name":12,"@type":39,"position":26},"https://docshare.wps.com/document/healthcare/",{"item":47,"name":13,"@type":39,"position":48},"https://docshare.wps.com/document/lincosamides/27819",4,{"url":47,"name":13,"@type":50,"author":51,"headline":13,"publisher":53,"fileFormat":56,"description":14,"dateModified":57,"datePublished":57,"encodingFormat":56,"isAccessibleForFree":58,"interactionStatistic":59},"DigitalDocument",{"name":9,"@type":52},"Person",{"url":37,"name":54,"@type":55},"DocShare","Organization","application/pdf","2026-05-08",true,{"@type":60,"interactionType":61,"userInteractionCount":4},"InteractionCounter",{"@type":62},"ViewAction","https://schema.org",{"og:url":47,"og:type":65,"og:title":13,"og:site_name":54,"og:description":14},"article",{"robots":67,"canonical":47},"index,follow",{"doc_id":7,"site_id":23},{"code":4,"msg":5,"data":70},[71,75,79,83,88,93,96,101,106,109,113],{"id":20,"doc_module":4,"doc_module_name":42,"category_name":72,"show_sort_weight":73,"slug":74},"Story & Novel",90,"story-novel",{"id":43,"doc_module":4,"doc_module_name":42,"category_name":76,"show_sort_weight":77,"slug":78},"Literature",80,"literature",{"id":48,"doc_module":4,"doc_module_name":42,"category_name":80,"show_sort_weight":81,"slug":82},"Exam",70,"exam",{"id":84,"doc_module":4,"doc_module_name":42,"category_name":85,"show_sort_weight":86,"slug":87},5,"Comic",60,"comic",{"id":89,"doc_module":4,"doc_module_name":42,"category_name":90,"show_sort_weight":91,"slug":92},6,"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":42,"category_name":12,"show_sort_weight":94,"slug":95},40,"healthcare",{"id":97,"doc_module":4,"doc_module_name":42,"category_name":98,"show_sort_weight":99,"slug":100},8,"Research & Report",30,"research-report",{"id":102,"doc_module":4,"doc_module_name":42,"category_name":103,"show_sort_weight":104,"slug":105},9,"Religion & Spirituality",20,"religion-spirituality",{"id":104,"doc_module":4,"doc_module_name":42,"category_name":107,"show_sort_weight":104,"slug":108},"World Cup","world-cup",{"id":110,"doc_module":4,"doc_module_name":42,"category_name":111,"show_sort_weight":110,"slug":112},10,"Lifestyle","lifestyle",{"id":114,"doc_module":4,"doc_module_name":42,"category_name":115,"show_sort_weight":84,"slug":116},19,"General","general"]