[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-421648-105":3,"detail-sidebar-cat-0-en-105":85,"doc-detail-421648-en":134},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":78,"head_meta":80,"extra_data":82,"updated_unix":84},105,"en","life-satisfaction-and-risk-of-dementia-evidence-from-two-prospective-samples","Life Satisfaction and Risk of Dementia - Evidence From Two Prospective Samples","","Life satisfaction and incident dementia are examined using two large, prospective population-based cohorts from 15 European countries. English Longitudinal Study of Ageing (ELSA) and Survey of Health, Ageing and Retirement in Europe (SHARE) data were analyzed with Cox proportional hazards regression. Higher life satisfaction showed an association with roughly 20% lower dementia risk in both samples. The relationship was not moderated by key sociodemographic or depressive factors and was robust to age restriction and early dementia exclusion. Results support life satisfaction as a potential intervention target for healthier cognitive aging.",{"@graph":14,"@context":77},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/life-satisfaction-and-risk-of-dementia-evidence-from-two-prospective-samples/421648/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/life-satisfaction-and-risk-of-dementia-evidence-from-two-prospective-samples/421648.png","ImageObject",300,407,{"name":42,"@type":43},"Sarah ","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",9,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69,73],{"name":60,"@type":61,"acceptedAnswer":62},"What was the main goal of the study?","Question",{"text":63,"@type":64},"To assess whether life satisfaction is associated with a lower risk of incident dementia using two large prospective cohorts.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"Which datasets and sample characteristics were analyzed?",{"text":68,"@type":64},"ELSA (N=6979) and SHARE (N=24119) from 15 European countries were analyzed, with follow-up means around 11 years and incident dementia cases reported for each cohort.",{"name":70,"@type":61,"acceptedAnswer":71},"How strong was the association between life satisfaction and dementia risk?",{"text":72,"@type":64},"Higher life satisfaction corresponded to about a 20% lower risk of dementia in both samples.",{"name":74,"@type":61,"acceptedAnswer":75},"Did the association vary by demographic or depressive factors?",{"text":76,"@type":64},"No; it was not moderated by sex, education, race, marital status, presence of children, or depressive symptoms, and remained similar in robustness analyses.","https://schema.org",{"og:url":32,"og:type":79,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":81,"canonical":32},"index,follow",{"doc_id":83,"site_id":7},421648,1790789812,{"code":4,"msg":86,"data":87},"success",[88,92,96,100,105,110,114,119,123,126,130],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":97,"show_sort_weight":98,"slug":99},"Exam",70,"exam",{"id":101,"doc_module":4,"doc_module_name":25,"category_name":102,"show_sort_weight":103,"slug":104},5,"Comic",60,"comic",{"id":106,"doc_module":4,"doc_module_name":25,"category_name":107,"show_sort_weight":108,"slug":109},6,"Technology",50,"technology",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":112,"slug":113},7,40,"healthcare",{"id":115,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},8,"Research & Report",30,"research-report",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":121,"slug":122},"Religion & Spirituality",20,"religion-spirituality",{"id":121,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":121,"slug":125},"World Cup","world-cup",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":127,"slug":129},10,"Lifestyle","lifestyle",{"id":131,"doc_module":4,"doc_module_name":25,"category_name":132,"show_sort_weight":101,"slug":133},19,"General","general",{"code":4,"msg":86,"data":135},{"doc_id":83,"user_id":136,"nickname":42,"user_avatar":137,"doc_module":4,"category_id":111,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":138,"file_id":139,"file_url":140,"file_type":141,"file_size":142,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":22,"language":143,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":144,"faqs":145,"seo_title":146,"seo_description":12,"update_tm":147,"read_time":30,"preview_page_count":4},962085320529,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc","Innovation in Aging, 2025, Vol. 9, No. S2 39  \npresence of children), psychological (depression), behavioral (physical activity and smoking), and clinical (obesity, diabetes, hypertension) risk factors. The association between life satisfaction and incident dementia was not moderated by sex, education, race, marital status, presence of children, or depressive symptoms in either sample. The associations were similar when the sample was restricted to participants 65 years and older and when participants who developed dementia within 5 years were excluded. The findings suggest that life satisfaction is a potential intervention target to reduce dementia risk and support healthier cognitive aging.  \nAbstract citation ID: igaf122.128  \nLIFE SATISFACTION AND RISK OF DEMENTIA:  \nEVIDENCE FROM TWO PROSPECTIVE SAMPLES  \nSelin Karakose1, Martina Luchetti2, Yannick Stephan3, Angelina R. Sutin2, and Antonio Terracciano1, 1. Florida State University, Tallahassee, Florida, United States, 2. Florida State University College of Medicine, Tallahassee, Florida, United States, 3. University of Montpellier, Montpellier, Languedoc-Roussillon, France  \nLife satisfaction predicts better physical and mental health outcomes. There is promising evidence that its positive contribution may extend to healthier cognitive outcomes, including incident dementia. Samples from more countries are needed to evaluate the replicability and robustness of this association. This study examines the association between life satisfaction and dementia in two large, prospective, population-based cohorts from 15 European countries. Data from the English Longitudinal Study of Ageing (ELSA: N = 6979, 56.1% female; Mean age=65.35; Follow-up mean=11.27 years; 498 incident dementia) and the Survey of Health and Ageing and Retirement in Europe (SHARE: N =24119, 55.5% female; Mean age=64.50; Follow-up  \nmean: 10.90 years; 1655 incident dementia) were analyzed using Cox proportional hazards regression. In both samples, higher life satisfaction was associated with about 20% lower risk of dementia, an association that remained significant accounting for demographic (age, sex, race, education, marital status, and","cbCaib6KUsnCWFKo","https://ap.wps.com/l/cbCaib6KUsnCWFKo","pdf",117971,"English","# Study objective\n## Cohorts and participants\n## Statistical analysis\n## Main findings\n## Robustness and moderation checks\n## Implications","[{\"question\":\"What was the main goal of the study?\",\"answer\":\"To assess whether life satisfaction is associated with a lower risk of incident dementia using two large prospective cohorts.\"},{\"question\":\"Which datasets and sample characteristics were analyzed?\",\"answer\":\"ELSA (N=6979) and SHARE (N=24119) from 15 European countries were analyzed, with follow-up means around 11 years and incident dementia cases reported for each cohort.\"},{\"question\":\"How strong was the association between life satisfaction and dementia risk?\",\"answer\":\"Higher life satisfaction corresponded to about a 20% lower risk of dementia in both samples.\"},{\"question\":\"Did the association vary by demographic or depressive factors?\",\"answer\":\"No; it was not moderated by sex, education, race, marital status, presence of children, or depressive symptoms, and remained similar in robustness analyses.\"}]","Life Satisfaction and Risk of Dementia - Evidence From Two Prospective Samples | PDF",1790625321]