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A 42-year-old woman presented with sudden slurred speech and transient right-sided weakness. Initial CT brain and angiography were normal, while MRI showed multiple small infarcts consistent with embolic strokes. Transthoracic echocardiography identified a large left atrial myxoma as the likely embolic source. She underwent successful surgical excision with progressive neurological improvement and no persistent deficits, though transient postoperative atrial fibrillation required anticoagulation.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/left-atrial-myxoma-presenting-as-multiple-embolic-strokes-in-a-young-female-case-report/432847/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/left-atrial-myxoma-presenting-as-multiple-embolic-strokes-in-a-young-female-case-report/432847.png","ImageObject",300,407,{"name":92,"@type":93},"Muffet","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-06","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What were the initial symptoms and early imaging findings in the reported case?","Question",{"text":112,"@type":113},"The patient presented with sudden slurred speech and transient right-sided weakness. Initial brain CT and angiography were normal, with no acute findings.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the embolic source identified?",{"text":117,"@type":113},"MRI revealed multiple small infarcts consistent with embolic strokes, and transthoracic echocardiography identified a large left atrial myxoma as the likely embolic source.",{"name":119,"@type":110,"acceptedAnswer":120},"What was the treatment and postoperative outcome?",{"text":121,"@type":113},"The patient underwent successful surgical excision of the mass shortly after diagnosis. She showed progressive neurological improvement with no persistent focal deficits, though she developed transient postoperative atrial fibrillation requiring anticoagulation.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},432847,1790696347,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},962090768927,"https://ap-avatar.wpscdn.com/davatar_085a072bc5b1113ac321206ff7593b45","Review began 11/10/2025  \nReview ended 12/01/2025  \nPublished 12/05/2025  \n© Copyright 2025  \nSingh et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nDOI: 10.7759/cureus.98515  \nOpen Access Case Report  \nLeft Atrial Myxoma Presenting As Multiple Embolic Strokes in a Young Female: A Case Report  \nMandeep Singh 1, John Habashi 1, Tanvir Hassan 1, Anil Agarwal 1  \n1. General Internal Medicine, Princess Alexandra Hospital, Harlow, GBR Corresponding author: Mandeep Singh, [msbagga16.3@gmail.com](msbagga16.3@gmail.com)  \nAbstract  \nCardiac myxomas are rare benign tumors that can occasionally present with neurological complications due to embolic phenomena. We report a case of a 42-year-old woman who presented with sudden-onset slurred speech and transient right-sided weakness. Initial computed tomography (CT) of the brain and angiography were normal. Magnetic resonance imaging (MRI) revealed multiple small infarcts consistent with embolic strokes. Transthoracic echocardiography identified a large left atrial myxoma as the likely embolic source. The patient underwent successful surgical excision of the mass shortly after diagnosis. Neurologically, she showed progressive clinical improvement with no persistent focal deficits at postoperative follow-up, although she developed transient postoperative atrial fibrillation requiring anticoagulation. This case underscores the importance of early consideration of cardiac etiologies in young patients with multifocal embolic stroke and highlights the role of prompt echocardiographic evaluation and timely surgical management to prevent recurrent embolization.  \nCategories: Neurology, Cardiology, Internal Medicine  \nKeywords: cardiac tumour, case report, cryptogenic stroke, embolic stroke, left atrial myxoma  \nIntroduction  \nCardiac myxomas are the most common primary cardiac tumours, accounting for nearly 50% of all benign cardiac neoplasms, with approximately 75% arising from the left atrium, typically from the interatrial septum near the fossa ovalis [1] . Although histologically benign, their clinical significance stems from their potential to cause serious complications through embolic, obstructive, and constitutional mechanisms. The tumours are more frequently diagnosed in women, most commonly between the third and sixth decades of life [2] . Clinically, cardiac myxomas are notorious for their variable and often nonspecific presentation. Symptoms may mimic other cardiac or systemic conditions, usually delaying diagnosis. The classic triad of clinical manifestations includes obstructive features due to impaired intracardiac blood flow, embolic phenomena from tumor fragments or associated thrombi, and constitutional symptoms such as fever, malaise, or weight loss due to cytokine release [3] . Among these, embolic manifestations are particularly important because they may lead to cerebrovascular events, myocardial infarction, or peripheral arterial occlusion [4] . Approximately 30-40% of patients with atrial myxomas experience systemic embolization, and the central nervous system is the most frequent target [5] .  \nIn younger individuals without conventional vascular risk factors, embolic stroke can often be the first presentation of an underlying cardiac myxoma. Therefore, identifying cardiac sources of emboli in cases of cryptogenic stroke is of critical diagnostic and therapeutic importance. Echocardiography remains the primary diagnostic modality, with transthoracic echocardiography (TTE) detecting most lesions and transesophageal echocardiography (TEE) offering enhanced sensitivity for smaller or atypically located tumors [6] . Surgical excision is curative and usually results in excellent long-term outcomes when performed promptly [7] .  \nWe report the case of a 42-year-old woman ","cbCail7C2lZHyyPi","https://ap.wps.com/l/cbCail7C2lZHyyPi","pdf",1758387,"English","# Abstract\n# Introduction\n# Case Presentation\n## Clinical findings\n## Imaging and diagnosis","[{\"question\":\"What were the initial symptoms and early imaging findings in the reported case?\",\"answer\":\"The patient presented with sudden slurred speech and transient right-sided weakness. Initial brain CT and angiography were normal, with no acute findings.\"},{\"question\":\"How was the embolic source identified?\",\"answer\":\"MRI revealed multiple small infarcts consistent with embolic strokes, and transthoracic echocardiography identified a large left atrial myxoma as the likely embolic source.\"},{\"question\":\"What was the treatment and postoperative outcome?\",\"answer\":\"The patient underwent successful surgical excision of the mass shortly after diagnosis. She showed progressive neurological improvement with no persistent focal deficits, though she developed transient postoperative atrial fibrillation requiring anticoagulation.\"}]","Left Atrial Myxoma Presenting As Multiple Embolic Strokes in a Young Female - Case Report | PDF",1790661605,13]