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The book provides thorough foundations in statistical physics (Chapters 1–10) and then shifts to biological applications (Chapters 11–16), covering primary, secondary, and tertiary structures and the formation mechanisms underlying interactions. It emphasizes theoretical principles with references to standard sources for empirical details and provides a broad set of reproduced key figures from cited works.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/lectures-on-statistical-physics-and-protein-folding-foreword-contents/326843/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/lectures-on-statistical-physics-and-protein-folding-foreword-contents/326843.png","ImageObject",300,407,{"name":92,"@type":93},"Riley","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-23","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":19},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main focus of these lectures?","Question",{"text":112,"@type":113},"The lectures introduce biological research on protein structure using the principles and tools of statistical physics.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How is the book organized between statistical physics and biological applications?",{"text":117,"@type":113},"Chapters 1–10 provide an in-depth introduction to statistical physics, while Chapters 11–16 focus more specifically on protein and biophysical applications.",{"name":119,"@type":110,"acceptedAnswer":120},"What topics are covered in the “life process” discussion?",{"text":121,"@type":113},"It begins with primary, secondary, and tertiary protein structures and ends with working hypotheses for the principles governing formation and interaction of secondary and tertiary structures.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},326843,1790722597,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":19,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},1374391975076,"https://ap-avatar.wpscdn.com/avatar/14000253ca4ec9f6853?x-image-process=image/resize,m_fixed,w_180,h_180&k=1783305029341752051","This page intentionally left blank  \nPublished by  \nWorld Scientific Publishing Co. Pte. Ltd.  \n5 Toh Tuck Link, Singapore 596224  \nUSA office: 27 Warren Street, Suite 401-402, Hackensack, NJ 07601  \nUK office: 57 Shelton Street, Covent Garden, London WC2H 9HE  \nBritish Library Cataloguing-in-Publication Data  \nA catalogue record for this book is available from the British Library.  \nFirst published 2005 Reprinted 2006  \nLECTURES ON STATISTICAL PHYSICS AND PROTEIN FOLDING  \nCopyright © 2005 by World Scientific Publishing Co. Pte. Ltd.  \nAll rights reserved. This book, or parts thereof, may not be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system now known or to be invented, without written permission from the Publisher.  \nFor photocopying of material in this volume, please pay a copying fee through the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. In this case permission to photocopy is not required from the publisher.  \nISBN 981-256-143-9  \nISBN 981-256-150-1 (pbk)  \nTypeset by Stallion Press  \nEmail: [enquiries@stallionpress.com](enquiries@stallionpress.com)  \n[Printed in Singapore.](Printed in Singapore.)  \nForeword  \nThis book comprises a series of lectures given by the author atthe Zhou Pei-Yuan Center for Applied Mathematics at Tsinghua University to introduce research in biology — specifically, protein structure—to individuals with a background in other sciences that also includes a knowledge in statistical physics. This is a timely publication, since the current perception is that biology and biophysics will undergo rapid development through applications of the principles of statistical physics, including statistical mechanics, kinetic theory, and stochastic processes.  \nThe chapters begin with a good thorough introduction to statistical physics (Chapters 1–10) . The presentation is somewhat tilted towards biological applications in the second part of the book (Chapters 11–16) . Specific biophysical topics are then presented in this style while the general mathematical/physical principles, such as self-avoiding random walk and turbulence (Chapter 15), are further developed.  \nThe discussion of “life process” begins with Chapter 11, where the basic topics of primary, secondary and tertiary structures are covered. This discussion ends with Chapter 16, in which working hypotheses are suggested for the basic principles that govern the formation and interaction of the secondary and tertiary structures. The author has chosen to avoid a more detailed discussion on empirical information; instead, references are given to standard publications. Readers who are interested in pursuing further in these directions are recommended to study Mechanisms of Protein Folding edited by Roger H. Pain (Oxford, 2000) . Traditionally, the prediction of protein structure from its amino acid sequence has occupied the central position in the study of protein structure. Recently, however, there is a shift of emphasis towards the study of mechanisms. Readers interested  \nvi Foreword  \nin these general background information for better understanding of the present book are recommended to consult Introduction to Protein Structure by Carl Branden and John Tooze (Garland, 1999) . Another strong point in this volume is the wide reproduction of key figures from these sources.  \nProtein structure is a complex problem. As is true with all complex issues, its study requires several different parallel approaches, which usually complement one another. Thus, we would expect that, in the long term, a better understanding of the mechanism of folding would contribute to the development of better methods of prediction. We look forward to the publication of a second edition of this volume in a few years in which all these new developments will be found in detail. Indeed, both of the two influential books cited above are in the second edition. ","cbCaidQEPGUgMLjc","https://ap.wps.com/l/cbCaidQEPGUgMLjc","pdf",2928270,159,"English","# Foreword\n# Contents\n## Introduction\n## Entropy\n## Maxwell–Boltzmann Distribution\n## Free Energy\n## Chemical Potential\n## Phase Transitions\n## Kinetics of Phase Transitions\n## The Order Parameter\n## Correlation Function","[{\"question\":\"What is the main focus of these lectures?\",\"answer\":\"The lectures introduce biological research on protein structure using the principles and tools of statistical physics.\"},{\"question\":\"How is the book organized between statistical physics and biological applications?\",\"answer\":\"Chapters 1–10 provide an in-depth introduction to statistical physics, while Chapters 11–16 focus more specifically on protein and biophysical applications.\"},{\"question\":\"What topics are covered in the “life process” discussion?\",\"answer\":\"It begins with primary, secondary, and tertiary protein structures and ends with working hypotheses for the principles governing formation and interaction of secondary and tertiary structures.\"}]","LECTURES ON STATISTICAL PHYSICS AND PROTEIN FOLDING - Foreword - Contents | PDF",1789975531,401]