[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-366082-105":59,"doc-detail-366082-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","lateral-lymph-node-dissection-combined-with-endoscopic-submucosal-dissection-for-early-rectal-cancer-complicated-with-ulcerative-colitis-a-case-report","Lateral lymph node dissection combined with endoscopic submucosal dissection for early rectal cancer complicated with ulcerative colitis - A case report","","Early rectal cancer (Stage 0) is usually limited to the mucosa or submucosa, so lymph node metastasis is rare and endoscopic resection can be curative. When enlarged lateral lymph nodes are detected with uncertain etiology, additional surgery may be necessary. This case report describes a 66-year-old man with ulcerative colitis and blood in stool, whose right-sided 263D nodes were later diagnosed as reactive hyperplasia after combined lateral lymph node dissection and endoscopic submucosal dissection, achieving complete tumor removal with negative margins.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/lateral-lymph-node-dissection-combined-with-endoscopic-submucosal-dissection-for-early-rectal-cancer-complicated-with-ulcerative-colitis-a-case-report/366082/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/lateral-lymph-node-dissection-combined-with-endoscopic-submucosal-dissection-for-early-rectal-cancer-complicated-with-ulcerative-colitis-a-case-report/366082.png","ImageObject",300,407,{"name":92,"@type":93},"Rizky","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why was combined lateral lymph node dissection and endoscopic submucosal dissection considered in this case?","Question",{"text":113,"@type":114},"Enlarged lateral lymph nodes were detected preoperatively, and their nature could not be determined. Lateral lymph node dissection was used to rule out metastasis, followed by endoscopic submucosal dissection to remove the tumor.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What did imaging and pathology show for the enlarged lymph nodes?",{"text":118,"@type":114},"Pelvic MRI and enhanced CT showed enlarged right group 263D lymph nodes (~1.2 cm) with well-defined borders. After lateral lymph node dissection, pathology diagnosed reactive hyperplasia rather than metastatic disease.",{"name":120,"@type":111,"acceptedAnswer":121},"What were the main outcomes after treatment?",{"text":122,"@type":114},"The patient recovered well after surgery. Pathology confirmed reactive hyperplasia of lymph nodes, and the tumor was completely resected with negative margins.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},366082,1790196883,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":81,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":39},962085564807,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","®  \n Clinical Case Report   \nLateral lymph node dissection combined with endoscopic submucosal dissection for early rectal cancer complicated with ulcerative colitis  \nA case report  \nBaosu Huang, MMa , Bing Zhu, MMb , RunZhi Liu, MMa , Bin Ren, MDa ,*  \n\n| Abstract\u003Cbr>Rationale: Early rectal cancer is mostly confined to the mucosa or submucosa, and metastasis to lymph nodes is rare. Stage 0 rectal cancer can usually be cured by endoscopic resection. However, when patients present with enlarged lateral lymph nodes of uncertain nature, additional surgical intervention should be considered. This article reports a case of early rectal cancer combined with ulcerative colitis. Preoperative imaging examination revealed enlarged right-sided group 263D lymph nodes. Since the nature of the enlarged lymph nodes cannot be determined, it was decided to perform lateral lymph node dissection combined with endoscopic submucosal dissection to achieve clear diagnosis and treatment. This article aims to illustrate the importance of individualized treatment for patients with early rectal cancer with complex clinical backgrounds and the clinical value of lateral lymph node dissection combined with endoscopic submucosal dissection.\u003Cbr>Patient concerns: The patient was a 66-year-old male who presented with blood in the stool for 1 month with no family history of hereditary tumors.\u003Cbr>Diagnosis: Colonoscopy and further biopsy diagnosed early rectal malignancy (stage 0) . Pelvic magnetic resonance and enhanced computed tomography showed enlarged right group 263D lymph nodes with well-defined borders, approximately 1.2 cm in diameter. Together with the patient’s history, the possibility of metastasis of rectal cancer was considered, but the lymph nodes were diagnosed as reactive hyperplasia after lateral lymph node dissection.\u003Cbr>Interventions: Since the nature of the enlarged lymph nodes could not be determined, it was decided to first perform lateral lymph node dissection to rule out the possibility of metastasis, followed by endoscopic submucosal dissection to remove the tumor.\u003Cbr>Outcomes: The patient recovered well after surgery. Pathological examination showed reactive hyperplasia of the lymph nodes, and the tumor was completely resected with negative margins.\u003Cbr>Lessons: Lymph node metastases rarely occur in early rectal cancer, but this possibility should not be ignored, especially when dealing with patients with complex clinical backgrounds. This case also emphasizes the importance of individualized diagnosis as well as the extremely high clinical value of Lateral lymph node dissection combined with endoscopic submucosal dissection, and provides a reference for the diagnosis and treatment of similar cases.\u003Cbr>Abbreviations: CT = computed tomography, ERC = early rectal cancer, ESD = endoscopic mucosal dissection, LLND = lateral lymph node dissection, MR = magnetic resonance, UC = ulcerative colitis. |\n| --- |\n| Keywords: combined laparoscopic-endoscopic technique, Early rectal cancer, endoscopic submucosal dissection, lateral lymph node dissection, ulcerative colitis |\n\nWritten informed consent was obtained from all participants.  \nThe authors have no funding and conflicts of interest to disclose.  \nData sharing not applicable to this article as no datasets were generated or analyzed during the current study.  \nAll procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.  \na Affiliated Hospital of Shandong Second Medical University, School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China, b School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.  \n* Correspondence: Bin Ren, Gastrointestinal Surgery, Affiliated Hospital of Shandong Second Medical University, No. 4948, Sheng","cbCaieZfL6GEtHEo","https://ap.wps.com/l/cbCaieZfL6GEtHEo","pdf",572724,"English","# Introduction\n## Ulcerative colitis and rectal cancer risk\n## Early rectal cancer treatment and lateral lymph node metastasis\n# Case report (abstract summary)\n## Patient concerns and diagnosis\n## Interventions and outcomes\n## Lessons learned","[{\"question\":\"Why was combined lateral lymph node dissection and endoscopic submucosal dissection considered in this case?\",\"answer\":\"Enlarged lateral lymph nodes were detected preoperatively, and their nature could not be determined. Lateral lymph node dissection was used to rule out metastasis, followed by endoscopic submucosal dissection to remove the tumor.\"},{\"question\":\"What did imaging and pathology show for the enlarged lymph nodes?\",\"answer\":\"Pelvic MRI and enhanced CT showed enlarged right group 263D lymph nodes (~1.2 cm) with well-defined borders. After lateral lymph node dissection, pathology diagnosed reactive hyperplasia rather than metastatic disease.\"},{\"question\":\"What were the main outcomes after treatment?\",\"answer\":\"The patient recovered well after surgery. Pathology confirmed reactive hyperplasia of lymph nodes, and the tumor was completely resected with negative margins.\"}]","Lateral lymph node dissection combined with endoscopic submucosal dissection for early rectal cancer complicated with ulcerative colitis - A case report | PDF",1790163773]