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Data from 612 valid responses showed mean scores of 9.25 for knowledge (0–23), 35.68 for attitudes (10–50), and 24.03 for practices (8–40). Multivariate logistic regression linked higher attitude scores to more proactive practices, while path analysis demonstrated direct effects of knowledge on attitude and attitude on practice, plus an indirect knowledge-to-practice pathway.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/knowledge-attitudes-and-practices-of-hand-eczema-patients-in-guangdong-china/410906/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/knowledge-attitudes-and-practices-of-hand-eczema-patients-in-guangdong-china/410906.png","ImageObject",300,407,{"name":92,"@type":93},"Fahsai","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-04","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What was the purpose of this study on hand eczema in Guangdong, China?","Question",{"text":113,"@type":114},"To assess patients’ knowledge, attitudes, and practices regarding hand eczema and identify gaps that may hinder effective self-management.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How were KAP outcomes measured and analyzed?",{"text":118,"@type":114},"The study used a self-designed KAP questionnaire and summarized knowledge, attitude, and practice scores; multivariate logistic regression and path analysis were then applied to test relationships among KAP components.",{"name":120,"@type":111,"acceptedAnswer":121},"What key relationships did the study find among knowledge, attitudes, and practices?",{"text":122,"@type":114},"Higher attitude scores were independently associated with more proactive practices. 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Patil,  \nDY Patil Deemed to be University, India Zilu Qu,  \nWuhan Hospital of Traditional Chinese and Western Medicine, China  \n*CORRESPONDENCE  \nJia Liao  \n [liaojia1014@163.com](liaojia1014@163.com)  \nRECEIVED 16 September 2025  \nREVISED 21 November 2025  \nACCEPTED 25 November 2025  \nPUBLISHED 18 December 2025  \nCITATION  \nZheng J, Zhao S, Huang X, Yao X, Chen Q, Tan M and Liao J (2025) Knowledge, attitudes, and practices of hand eczema patients in Guangdong, China.  \nFront. Public Health 13:1706796 .  \ndoi: 10.3389/fpubh.2025.1706796  \nCOPYRIGHT  \n© 2025 Zheng, Zhao, Huang, Yao, Chen, Tan and Liao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.  \nKnowledge, attitudes, and practices of hand eczema patients in Guangdong, China  \nJiecheng Zheng 1, Shaoling Zhao 1, Xueyi Huang 1, Xin Yao 1, Qing Chen 2, Min Tan 1 and Jia Liao 1*  \n1Department of Dermatology, Zhongshan Second People's Hospital, Zhongshan, Guangdong, China, 2School of Humanities and Social Science, Zhongshan Institute, University of Electronic Science and Technology of China, Zhongshan, Guangdong, China  \nBackground: Hand eczema is a common, debilitating condition affecting quality of life. This study aimed to assess the knowledge, attitudes, and practices (KAP) of patients with hand eczema in Guangdong, China, toward their condition. Methods: A cross-sectional study was conducted at our hospital from September 21, 2023, to July 31, 2024, using a self-designed KAP questionnaire.  \nResults: A total of 612 valid questionnaires were collected. The mean (SD) scores for knowledge, attitude, and practice were 9.25 (2 . 55) (possible range: 0–23), 35.68 (6 .02) (possible range: 10–50), and 24.03 (5 . 18) (possible range: 8–40), respectively. Multivariate logistic regression indicated that a higher attitude score (OR = 1. 209, p \u003C 0.001) was independently associated with more proactive practices. The path analysis revealed that knowledge directly influenced attitude (β = 0. 191, p \u003C 0.001), and attitude had a direct effect on practice (β = 0. 591, p \u003C 0.001) . Additionally, knowledge indirectly affected practice through attitude (β = 0. 113, p \u003C 0.001) .  \nConclusion: Our findings highlight a significant gap in patient knowledge, suggesting that targeted educational interventions may be a valuable strategy to improve self-management. Future research should test the efficacy of such interventions.  \nKEYWORDS  \nhand eczema, knowledge, attitudes, practices, cross-sectional study  \nIntroduction  \nHand eczema, also known as dermatitis, is one of the most common types of eczema, primarily affecting the palms but also other parts of the hand. It is a prevalent condition, with a 1-year prevalence of up to 10% in the general population ( 1) . In China, recent studies have reported a prevalence ranging from 8.8 to 12.3% in the general population, with higher rates observed in certain occupational groups ( 1) . The main symptoms include dry, itchy skin, which may appear red or darker than the surrounding skin. Additional symptoms include cracking, soreness, and bleeding (2, 3), and in some cases, blisters may form. The affected skin often becomes dry, scaly, and thickened, and during flare-ups, the fingers can swell. This condition severely impacts patients’ quality of life, placing a significant burden on patients, both psychosocially and economically (4) . In more severe cases, chronic hand eczema can c","cbCaidRFtfpKrPlS","https://ap.wps.com/l/cbCaidRFtfpKrPlS","pdf",401983,"English","# Introduction\n## Background and burden of hand eczema\n## KAP model and rationale\n# Methods\n## Study design and questionnaire\n# Results\n## Participant characteristics and KAP scores\n## Regression and path analysis findings\n# Conclusion\n## Knowledge gaps and implications for education","[{\"question\":\"What was the purpose of this study on hand eczema in Guangdong, China?\",\"answer\":\"To assess patients’ knowledge, attitudes, and practices regarding hand eczema and identify gaps that may hinder effective self-management.\"},{\"question\":\"How were KAP outcomes measured and analyzed?\",\"answer\":\"The study used a self-designed KAP questionnaire and summarized knowledge, attitude, and practice scores; multivariate logistic regression and path analysis were then applied to test relationships among KAP components.\"},{\"question\":\"What key relationships did the study find among knowledge, attitudes, and practices?\",\"answer\":\"Higher attitude scores were independently associated with more proactive practices. Knowledge directly influenced attitudes, attitudes directly affected practices, and knowledge also affected practices indirectly through attitudes.\"}]","Knowledge, attitudes, and practices of hand eczema patients in Guangdong, China | PDF",1790586804,25]