[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-415698-105":59,"doc-detail-415698-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","isolated-inguinal-tuberculous-lymphadenitis-case-report","Isolated inguinal tuberculous lymphadenitis - Case report","","Isolated inguinal tuberculous lymphadenitis (TL) without other pulmonary or extrapulmonary involvement is rare. A 74-year-old man presented with left inguinal lymph node swelling. Imaging showed a hypoechoic lymph node lacking the hilum and multinodular inguinal nodes on CT without lung lesions; T-SPOT.TB was positive. Excisional biopsy demonstrated caseous necrosis, confirming TL, highlighting that isolated inguinal lymphadenopathy can still require TL evaluation even when TB is not evident elsewhere.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/isolated-inguinal-tuberculous-lymphadenitis-case-report/415698/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/isolated-inguinal-tuberculous-lymphadenitis-case-report/415698.png","ImageObject",300,407,{"name":92,"@type":93},"Melati","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why is isolated inguinal tuberculous lymphadenitis difficult to recognize?","Question",{"text":113,"@type":114},"It is rare and occurs without other pulmonary or extrapulmonary TB involvement, so inguinal lymphadenopathy can mimic other inflammatory or malignant causes.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What tests supported the diagnosis of isolated inguinal TL in this case?",{"text":118,"@type":114},"Ultrasonography and CT showed characteristic inguinal lymph node findings, T-SPOT.TB was positive, and lymph node biopsy revealed caseous necrosis.",{"name":120,"@type":111,"acceptedAnswer":121},"What additional clinical course suggested a secondary bacterial infection?",{"text":122,"@type":114},"The lymph node size increased rapidly and localized pain and redness improved with antibiotics, indicating bacterial infection superimposed on TL.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},415698,1791273944,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":19,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":52,"preview_page_count":4},962085570644,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","IDCases 43 (2026) e02458  \nContents lists available at ScienceDirect  \nIDCases  \njournal [homepage:](homepage: www.elsevier.com/locate/idcases)[ www.elsevier.com/locate/idcases](homepage: www.elsevier.com/locate/idcases)  \n| Case report\u003Cbr>Isolated inguinal tuberculous lymphadenitis\u003Cbr>Hiroaki Shibahara a,* , Takayoshi Yamada b, Yoshimasa Nakanec, Shunsuke Nakagawa d, Yoriko Yamashita e\u003Cbr>a Shibahara Clinic, Toyota, Japan\u003Cbr>b Department of Internal Medicine, Toyota Kosei Hospital, Toyota, Japan c Department of Dermatology, Toyota Kosei Hospital, Toyota, Japan d Department of Surgery, Toyota Kosei Hospital, Toyota, Japan e Department of Pathology, Toyota Kosei Hospital, Toyota, Japan |  |\n| --- | --- |\n| A R T I C L E I N F O\u003Cbr>Keywords:\u003Cbr>Isolated inguinal tuberculous lymphadenitis Extrapulmonary tuberculosis | A B S T R A C T\u003Cbr>Isolated inguinal tuberculous lymphadenitis (TL) with no other pulmonary or extrapulmonary involvement is rare. A 74-year-old male patient presented with inguinal lymph node swelling at a primary care clinic. On palpation, the lymph node was polymorphic and soft in consistency, and ultrasonography revealed a hypoechoic node with the absence of the hilum and an intra-nodal strong echo. Referring to a tertiary care hospital, a computed tomography scan revealed multinodular inguinal lymph node without any active inflammatory lesions in the lung. The T-SPOT.TB assay was positive. An excisional biopsy of the lymph node revealed caseous necrosis on histopathological examination, and the patient was diagnosed with TL. Isolated inguinal lymphadenopathy, even in the absence of pulmonary involvement, necessitates consideration of TL in the diagnostic process. |\n\nIntroduction  \nInguinal tuberculous lymphadenitis (TL) is an uncommon manifestation of extrapulmonary tuberculosis (EPTB), which more frequently affects the cervical and axillary regions as a part of systemic disease [1–3]. Moreover, an isolated TL located solely in the inguinal region, without other pulmonary or extrapulmonary involvement, is a rarepresentation [4–9].  \nLymphadenopathy occurs following various infectious and noninfectious diseases, including mycobacterial or bacterial adenitis, fungal diseases, toxoplasmosis, tularemia, cat-scratch disease, sarcoidosis, non-specific hyperplasia, and primary or metastatic neoplasms [1]. An accurate diagnosis of TL depends on a structured and sequential diagnostic process, which critically includes a good medical history, physical examination, imaging techniques, microbiological investigations, and histopathological evaluations [1,10].  \nWe present a case ofan inguinal mass initially evaluated at a primary care clinic and subsequently referred to a tertiary care hospital, where the T-SPOT.TB assay and lymph node biopsy confirmed isolated inguinal TL without evidence of tuberculosis (TB) in any other organ.  \nCase  \nA 74-year-old male patient presented with a complaint of a left inguinal swelling at a primary care clinic. On physical examination, an enlarged, polymorphic, well-circumscribed, and soft inguinal lymph node measuring approximately 2 cm was revealed. Ultrasonography revealed a hypoechoic mass with the absence of the hilum, a short-tolong axis (S/L) ratio \u003C 0.5, and an intra-nodal strong echo (Fig. 1). An inflammatory rather than malignant process was suspected, and empirical cefalexin therapy was initiated. However, without clinical improvement, the patient was subsequently referred to the tertiary care hospital for further evaluation. There is no history of contact with individuals who had TB. Computed tomography revealed a multinodular inguinal lymph node (Fig. 2), with no active inflammatory lesions observed in the lungs. Tests for human immunodeficiency virus, hepatitis B virus, and hepatitis C virus were all negative, while the T-SPOT.TB assay was positive. The lymph node increased from 2 cm at the primary care clinic to 3 cm at hospital presentation and further enlarged to 4–5 cm wit","cbCaig8Jfo78mimM","https://ap.wps.com/l/cbCaig8Jfo78mimM","pdf",998317,"English","# Case report\n## Keywords and Abstract\n## Introduction\n## Case","[{\"question\":\"Why is isolated inguinal tuberculous lymphadenitis difficult to recognize?\",\"answer\":\"It is rare and occurs without other pulmonary or extrapulmonary TB involvement, so inguinal lymphadenopathy can mimic other inflammatory or malignant causes.\"},{\"question\":\"What tests supported the diagnosis of isolated inguinal TL in this case?\",\"answer\":\"Ultrasonography and CT showed characteristic inguinal lymph node findings, T-SPOT.TB was positive, and lymph node biopsy revealed caseous necrosis.\"},{\"question\":\"What additional clinical course suggested a secondary bacterial infection?\",\"answer\":\"The lymph node size increased rapidly and localized pain and redness improved with antibiotics, indicating bacterial infection superimposed on TL.\"}]","Isolated inguinal tuberculous lymphadenitis - Case report | PDF",1790602453]