[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-332073-105":59,"doc-detail-332073-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","invasive-papillary-carcinoma-of-the-breast-a-case-report","Invasive papillary carcinoma of the breast - A case report","","Invasive papillary carcinoma (IPC) of the breast is presented as a rare cancer subtype. The case described shows a large primary tumor with skin involvement, while surgical exploration found no axillary lymph node metastasis. Due to financial constraints, treatment was limited to anastrozole endocrine therapy at 1 mg/day for 5 years after surgery, without radiotherapy or chemotherapy. Follow-up over 2.5 years suggests a good prognosis. A literature review highlights diagnostic overlap with other papillary neoplasms, an age-associated prevalence, and a comparatively favorable prognosis with reduced invasiveness.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/invasive-papillary-carcinoma-of-the-breast-a-case-report/332073/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/invasive-papillary-carcinoma-of-the-breast-a-case-report/332073.png","ImageObject",300,407,{"name":92,"@type":93},"Eliana","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-04","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What characterizes invasive papillary carcinoma (IPC) in this case report?","Question",{"text":112,"@type":113},"The report describes IPC as a rare breast cancer subtype with a large tumor size and skin involvement, without axillary lymph node metastasis found during surgical exploration.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the patient treated after surgery?",{"text":117,"@type":113},"Because of financial constraints, the patient received endocrine therapy only: anastrozole at 1 mg/day for 5 years, without radiotherapy or chemotherapy.",{"name":119,"@type":110,"acceptedAnswer":120},"What does follow-up suggest about the patient’s prognosis?",{"text":121,"@type":113},"After discharge, follow-up over 2.5 years via phone every 3 months showed a good prognosis.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},332073,1790835262,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},4398048949847,"https://ap-avatar.wpscdn.com/avatar/400002536579ef2da7f?_k=1778318612642679267","ONCOLOGY LETTERS 28: 300, 2024  \nInvasive papillary carcinoma of the breast: A case report  \nSHIJING WANG 1 , QINGFU ZHANG2 , TANGBO ZHANG2 and XIAOYUN MAO 1  \n1Department of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China; 2Department of Pathology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China  \nReceived January 23, 2024; Accepted April 19, 2024  \nDOI: 10. 3892/ol.2024.14433  \nAbstract. Invasive papillary carcinoma (IPC) of the breast is a rare form of cancer. The current report documents a case of IPC characterized by a large tumor size and skin involvement. Surgical exploration revealed no evidence of axillary lymph node metastasis in breast cancer. Due to financial constraints, the patient opted solely for anastrozole endocrine therapy ata dosage of 1 mg/day for a period of 5 years post‑surgery, foregoing other treatments such as radiotherapy and chemo‑ therapy. Since discharge, 2.5 years have passed, during which the patient has been followed up via phone every 3 months, showing a good prognosis. A literature review indicated that IPC is prevalent amongst the elderly population and can be misdiagnosed due to its morphological, cytomorphological and immunophenotypic overlap with other types of papillary neoplasms. This tumor exhibits a more favorable prognosis compared with IDC, primarily attributed to its advanta‑ geous gene and molecular expression patterns, coupled with its decreased invasiveness. Despite limited evidence‑based research on the treatment of IPC, the present case report, albeit with limitations, underscores the importance of avoiding over‑treatment and suggests the feasibility of combining surgery with endocrine therapy for IPC.  \nIntroduction  \nBased on the latest data from the World Health Organization (WHO), breast cancer continues to be the most frequently diagnosed cancer among women, accounting for 11.6% of all cancer cases, and remains the leading cause of cancer‑related deaths in women, responsible for 6.9% of all cancer‑associated deaths (1) . With the rise in breast cancer incidence, there is also a proportional increase in the incidence of rare histologic subtypes (2). Invasive papillary carcinoma (IPC) is a rare type  \nCorrespondence to: Professor Xiaoyun Mao, Department of Breast Surgery, The First Affiliated Hospital of China Medical University, 155 Nanjing North Street, Heping, Shenyang, Liaoning 110001, P.R. China  \nE‑mail: [xymao@cmu.edu.cn](xymao@cmu.edu.cn)  \nKey words: invasive papillary carcinoma, rare breast cancer, pathology, treatment, prognosis  \nof breast cancer, accounting for \u003C1% of breast cancer cases inmost case series, and is commonly seen in postmenopausal women (3‑5) . In 2003, the WHO classified IPC as a type of invasive mammary carcinoma in Classification of Tumors of the Breast and Female Genital Organs (6) . Certain studies on IPC actually targeted variants of solid papillary carcinoma (SPC) or encapsulated papillary carcinoma (EPC) due to the lack of specificity in the description (3,7) . In 2012, the WHO defined IPC as aggressive adenocarcinoma in the fourth edition of Classification of Breast Tumors, with papillary structures accounting for >90% of the invasive part (8) . This definition was maintained without modification in the subsequent fifth edition of the classification (2019) (9) . Currently, research on IPC is limited to case reports and small retrospective studies (2,10‑12), which has resulted in a lack of understanding of this rare tumor. Diagnosing IPC can be difficult due to a lack of in‑depth knowledge and understanding, and there is currently no established standard treatment in the medical community. The present article reports an exceptional case of IPC. The disease course lasted for 2 years, and the lesion involved the skin; however, no breast cancer lymph node metastasis was found. The patient received only endocrine therapy after sur","cbCaiuJNPOn9QJpl","https://ap.wps.com/l/cbCaiuJNPOn9QJpl","pdf",6305365,11,"English","# Abstract\n# Introduction\n# Case report","[{\"question\":\"What characterizes invasive papillary carcinoma (IPC) in this case report?\",\"answer\":\"The report describes IPC as a rare breast cancer subtype with a large tumor size and skin involvement, without axillary lymph node metastasis found during surgical exploration.\"},{\"question\":\"How was the patient treated after surgery?\",\"answer\":\"Because of financial constraints, the patient received endocrine therapy only: anastrozole at 1 mg/day for 5 years, without radiotherapy or chemotherapy.\"},{\"question\":\"What does follow-up suggest about the patient’s prognosis?\",\"answer\":\"After discharge, follow-up over 2.5 years via phone every 3 months showed a good prognosis.\"}]","Invasive papillary carcinoma of the breast - A case report | PDF",1789996626,28]