[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-420550-105":59,"doc-detail-420550-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","intubation-related-uvular-necrosis-case-report-and-review","Intubation-Related Uvular Necrosis - Case Report and Review","","Uvular ischemia and necrosis are rare causes of sore throat after endotracheal extubation, typically from mechanical compression by the endotracheal tube. A 39-year-old man developed persistent throat pain after elective endotracheal intubation and was diagnosed clinically with uvular necrosis. Conservative, symptom-directed therapy including throat lozenges and phenol spray led to gradual improvement and near-complete resolution by postoperative day 8.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/intubation-related-uvular-necrosis-case-report-and-review/420550/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/intubation-related-uvular-necrosis-case-report-and-review/420550.png","ImageObject",300,407,{"name":92,"@type":93},"dawugda","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What usually causes uvular ischemia or necrosis after extubation?","Question",{"text":113,"@type":114},"Uvular tissue injury usually results from mechanical compression by the endotracheal tube, along with related factors such as midline placement, entrapment, or aggressive suctioning.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How is uvular necrosis diagnosed?",{"text":118,"@type":114},"It is diagnosed clinically based on recent endotracheal intubation and symptoms such as throat pain, dysphagia, or odynophagia; exam findings often include uvular edema and pharyngeal erythema.",{"name":120,"@type":111,"acceptedAnswer":121},"What treatment is recommended for uvular necrosis in this setting?",{"text":122,"@type":114},"Treatment is conservative and symptom-directed, using options such as acetaminophen, throat lozenges, and topical phenol sprays; corticosteroids may be used for significant edema or refractory pain, while antibiotics are considered only if secondary bacterial infection is suspected.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},420550,1790825416,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":81,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":39,"preview_page_count":4},3985747870947,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","Images in Hospital Medicine  \nIntubation-Related Uvular Necrosis  \nSimon Wu, MD1, Ashley Saito, MD1  \n1 Department of Medicine, VA Greater Los Angeles Healthcare System  \nJournal of Brown Hospital Medicine Vol. 5, Issue 1, 2025  \nArticle Information  \nKeywords: uvular necrosis, uvular ischemia, endotrachael intubation, sore throat  \n[https://doi.org/10.56305/001c.153863](https://doi.org/10.56305/001c.153863)  \nSubmitted: October 24, 2025 EST  \nAccepted: December 05, 2025 EST  \nPublished: January 01, 2026 EST  \nAbstract  \nUvular ischemia and necrosis are rare causes of sore throat in the post-extubation period. The tissue injury usually results from mechanical compression by the endotracheal tube. We present a case of a 39-year-old man who underwent endotracheal intubation for an elective knee surgery. Following extubation, he reported a persistent sore throat, and was diagnosed with uvular necrosis based on characteristic exam findings. He was successfully treated with conservative measures.  \nA 39-year-old man with a prior right anterior cruciate ligament rupture complicated by traumatic arthritis of the right knee presented for an elective right total knee arthroplasty. Per his preoperative airway exam, he was a Mallampati class II. He underwent general endotracheal anesthesia and was successfully intubated on the first attempt with a Macintosh laryngoscopy blade number 4 and a 7.5-mm endotracheal tube (ETT) . He was extubated and transferred to the post-anesthesia care unit with stable vital signs on room air.  \nOn post-operative day (POD) 4, the patient reported a sore throat, which had persisted since extubation on POD 0. He did not report any dysphagia, odynophagia, hoarseness, or dyspnea. On exam, his uvula was edematous with an ulcerated tip. There was no tonsillar enlargement, exudates, other oral lesions, or cervical lymphadenopathy (Figure 1) . He was afebrile with normal vital signs and no leukocytosis. The case was discussed with Otolaryngology, who felt his symptoms were likely due to uvular necrosis related to his recent intubation. Conservative management was recommended, and he was prescribed throat lozenges and phenol spray. His sore throat and uvular edema gradually improved with these measures. By POD 8, the previously seen ulceration on his uvula was no longer appreciated (Figure 2) . He was discharged to an acute rehabilitation unit to continue physical therapy.  \nSore throat is common in patients who have recently undergone endotracheal intubation. This non-specific pharyngeal irritation is usually rated as mild to moderate and lasts less than two days.1 Uvular ischemia or even necrosis are rare but notable causes of a persistent or severe sore throat following extubation. Uvular ischemia results from impaired blood flow to the uvula often due to  \nFigure 1. Uvula with marked edema and uvular tip with a whitish, ulcerated appearance on postoperative day 4.  \ncompression from midline placement of the ETT, uvular entrapment between the ETT and oral airway, or vigorous suctioning.2 Use of any oropharyngeal instrumentation, whether an artificial airway or suctioning device, is the major risk factor for uvular injury.3 Risk of uvular necrosis does not appear to differ significantly between ETTs and laryngeal mask airways. Male gender is a proposed risk factor as men have more non-fatty tissue in the neck and soft palate. With induction of general anesthe-  \nFigure 2. Resolution of the previously seen ulcerated uvular tip  \nsia, this soft tissue becomes flaccid and prone to compression by artificial instrumentation.3,4  \nUvular necrosis is diagnosed clinically based on symptoms such as throat pain, dysphagia, or odynophagia ina patient with recent endotracheal intubation, upper endoscopy, or bronchoscopy.2, 5 On exam, uvular edema  \nand pharyngeal erythema are common. If necrosis is present, the distal portion of the uvula may appear white or blanch. Recovery typically occurs within 2 weeks, with sloughing of ","cbCaivpNuSu1Ym8r","https://ap.wps.com/l/cbCaivpNuSu1Ym8r","pdf",233177,"English","# Article Information\n## Abstract\n## Case Presentation\n## Discussion\n## Disclosures / Conflicts of Interest\n## References","[{\"question\":\"What usually causes uvular ischemia or necrosis after extubation?\",\"answer\":\"Uvular tissue injury usually results from mechanical compression by the endotracheal tube, along with related factors such as midline placement, entrapment, or aggressive suctioning.\"},{\"question\":\"How is uvular necrosis diagnosed?\",\"answer\":\"It is diagnosed clinically based on recent endotracheal intubation and symptoms such as throat pain, dysphagia, or odynophagia; exam findings often include uvular edema and pharyngeal erythema.\"},{\"question\":\"What treatment is recommended for uvular necrosis in this setting?\",\"answer\":\"Treatment is conservative and symptom-directed, using options such as acetaminophen, throat lozenges, and topical phenol sprays; corticosteroids may be used for significant edema or refractory pain, while antibiotics are considered only if secondary bacterial infection is suspected.\"}]","Intubation-Related Uvular Necrosis - Case Report and Review | PDF",1790621444]