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The preface highlights the field’s shift from stress-induced immune suppression toward immune dysregulation and stress-induced inflammation as disease-promoting factors. It also emphasizes signaling pathways, genetic contributions, environmental exposures, and nutrition as critical modulators of immune function. 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Daruna  \nDepartment of Psychiatry, Ochsner Clinic Foundation  \nAMSTERDAM l BOSTON l HEIDELBERG l LONDON l NEW YORK l OXFORD PARIS l SAN DIEGO l SAN FRANCISCO l SINGAPORE l SYDNEY l TOKYO  \nAcademic Press is an imprint of Elsevier  \nAcademic Press is an imprint of Elsevier  \n32 Jamestown Road, London NW1 7BY, UK  \n225 Wyman Street, Waltham, MA 02451, USA  \n525 B Street, Suite 1800, San Diego, CA 92101-4495, USA  \nFirst edition 2004 Second edition 2012  \nCopyright 􀀁 2012 Elsevier Inc. All rights reserved.  \nNo part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher. Permissions may be sought directly from Elsevier’s Science & Technology Rights Department in Oxford, UK: phone (+44) (0) 1865 843830; fax (+44) (0) 1865 853333; email: [permissions@elsevier.com](permissions@elsevier.com. Alternatively)[. Alternatively](permissions@elsevier.com. Alternatively), visit the Science and Technology Books website [at](at www.elsevierdirect.com/rights)[ www.elsevierdirect.com](at www.elsevierdirect.com/rights)[/](at www.elsevierdirect.com/rights)[rights](at www.elsevierdirect.com/rights) for further information.  \nNotice  \nNo responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made.  \nBritish Library Cataloguing-in-Publication Data  \nA catalogue record for this book is available from the British Library  \nLibrary of Congress Cataloging-in-Publication Data  \nA catalog record for this book is available from the Library of Congress ISBN: 978-0-12-382049-5  \nFor information on all Academic Press publications visit our website at [elsevierdirect.com](elsevierdirect.com)  \nTypeset by TNQ Books and Journals Pvt Ltd.  \n[www.tnq.co.in](www.tnq.co.in)  \nPrinted and bound in United States of America  \n12 13 14 15 16 10 9 8 7 6 5 4 3 2 1  \nFor Brandon and Caroline  \nPreface  \nThis second edition of Introduction to Psychoneuroimmunology aims to keep pace with what is a rapidly expanding multidisciplinary field. Psychoneuroimmunology remains the scientific discipline best poised to elucidate the complex processes that underlie health. In the eight years since the publication of the first edition, the number of scientific articles using the term psychoneuroimmunology has doubled and many more relevant scientific developments have occurred across multiple disciplines. The early focus on stress-induced immune suppression has given way to a broader understanding of immune dysregulation. Stress-induced inflammation has emerged as an important disease promoting factor. It is now widely accepted that the immune system is a major culprit in many of the chronic health problems experienced in middle age. Research also has begun to uncover additional signaling pathways that act to modulate the impact of stress on the immune system and health. Genome wide association studies have shown that the genetic contribution to disease can be elusive and often accounts for only a small portion of the risk for a given disorder. Exposure to microbes and physical aspects of the environment including sources of nutrition have gained recognition as critical factors which influence immune function and contribute to the probability of specific diseases.  \nThe book has been updated to incorporate the aforementioned scientific developments. It is intended for students planning careers in medicine, nursing, psychology, public health, social work, or for anyone interested in the scientific basis for an integrative approach ","cbCaiiSifJnFIyrG","https://ap.wps.com/l/cbCaiiSifJnFIyrG","pdf",16812601,323,"English","# Preface\n## Field overview and updates\n## Intended audience and scope\n## Book structure and chapter focus","[{\"question\":\"What key developments does the second edition incorporate?\",\"answer\":\"The second edition updates the text to reflect a rapidly expanding multidisciplinary field, including a broader understanding of immune dysregulation and stress-induced inflammation, plus additional signaling pathways and recognized roles of genetics and environmental exposures.\"},{\"question\":\"Who is the book intended for?\",\"answer\":\"It is intended for students planning careers in medicine, nursing, psychology, public health, social work, and for anyone interested in the scientific basis for an integrative approach to healthcare.\"},{\"question\":\"How does the book structure its coverage?\",\"answer\":\"It begins with an overview in Chapter 1 of the topics covered in subsequent chapters, then places psychoneuroimmunology in a historical context, followed by focused chapters on the immune system and how endocrine and other tissues modulate immune function.\"}]","Introduction to Psychoneuroimmunology - Second Edition - Academic overview | PDF",1789941171,814]