[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-430341-105":59,"doc-detail-430341-en":135},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":128,"head_meta":130,"extra_data":132,"updated_unix":134},105,"en","intracardiac-echocardiography-for-left-ventricular-diastolic-function-assessment-during-atrial-fibrillation-ablation","Intracardiac echocardiography for left ventricular diastolic function assessment during atrial fibrillation ablation","","Left ventricular diastolic dysfunction is linked to atrial fibrillation development and to recurrence risk after ablation, yet the value of intracardiac echocardiography (ICE) for diastolic assessment during ablation had not been systematically evaluated. This single-center, prospective study assessed feasibility and utility of ICE-derived diastolic measures, compared them with transthoracic echocardiography (TTE), and related findings to directly recorded left atrial pressure (LAP). ICE parameters correlated with LAP and with post-procedure intravenous diuretic need.",{"@graph":69,"@context":127},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/intracardiac-echocardiography-for-left-ventricular-diastolic-function-assessment-during-atrial-fibrillation-ablation/430341/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/intracardiac-echocardiography-for-left-ventricular-diastolic-function-assessment-during-atrial-fibrillation-ablation/430341.png","ImageObject",300,407,{"name":92,"@type":93},"Valentina","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-01","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119,123],{"name":110,"@type":111,"acceptedAnswer":112},"What clinical problem does the study address?","Question",{"text":113,"@type":114},"It evaluates whether ICE can measure left ventricular diastolic function during atrial fibrillation ablation and whether these measurements reflect left atrial pressure and related outcomes.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How was left atrial pressure (LAP) defined in the study?",{"text":118,"@type":114},"Elevated LAP was defined as a direct measurement of ≥ 12 mmHg before atrial fibrillation ablation.",{"name":120,"@type":111,"acceptedAnswer":121},"Which ICE-derived parameters were associated with higher LAP?",{"text":122,"@type":114},"Several parameters showed significant associations, including peak tricuspid regurgitation velocity and average E/e′.",{"name":124,"@type":111,"acceptedAnswer":125},"What was the study’s conclusion about using ICE in AF ablation?",{"text":126,"@type":114},"ICE can assess diastolic function using traditional parameters that correlate with TTE diastolic function and LAP, and restrictive filling patterns were linked to the need for post-procedural intravenous diuretics.","https://schema.org",{"og:url":83,"og:type":129,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":131,"canonical":83},"index,follow",{"doc_id":133,"site_id":62},430341,1790694871,{"code":4,"msg":5,"data":136},{"doc_id":133,"user_id":137,"nickname":92,"user_avatar":138,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":139,"file_id":140,"file_url":141,"file_type":142,"file_size":143,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":52,"language":144,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":145,"faqs":146,"seo_title":147,"seo_description":67,"update_tm":148,"read_time":149,"preview_page_count":4},13056703020460,"https://ap-avatar.wpscdn.com/avatar/be000253dac470eee5d?_k=1778207105932848923","Journal of Interventional Cardiac Electrophysiology (2026) 69:53–62  \n[https://doi.org/10.1007/s10840-025-02110-y](https://doi.org/10.1007/s10840-025-02110-y)  \nORIGINAL RESEARCH  \nIntracardiac echocardiography for left ventricular diastolic function assessment during atrial fibrillation ablation  \nJian Liang Tan1 · Julio Chirinos2 · Darshak Patel1 · Dinesh Jagasia2 · Matthew C. Hyman1 · Gustavo S. Guandalini1 · Saman Nazarian1 · David Lin1 · Gregory Supple1 · David S. Frankel1 · David J. Callans1 · Francis E Marchlinski1 · Jian-Fang Ren2 · Timothy M. Markman1  \nReceived: 23 April 2025 / Accepted: 21 July 2025 / Published online: 27 August 2025 © The Author(s) 2025  \nAbstract  \nBackground Left ventricular (LV) diastolic dysfunction is associated with the development of atrial fibrillation (AF) and risk of recurrence after ablation. The use of an intracardiac echocardiography (ICE) for diastolic function assessment during ablation procedures has not been evaluated.  \nObjectives To evaluate the feasibility and utility of ICE obtained measures of LV diastolic function including peak tricuspid regurgitation velocity, trans-mitral flow velocity, mitral annular tissue Doppler velocities, and pulmonary vein flow velocities in patients undergoing AF ablation.  \nMethods We conducted a single-center, prospective evaluation of patients undergoing AF ablation between 2022 and 2024. During sinus rhythm, diastolic parameters were measured with the ICE catheter and direct left atrial pressure (LAP) was recorded prior toAF ablation. Elevated LAP was defined as ≥ 12 mmHg. ICE measured diastolic parameters were compared with those measured on transthoracic echocardiography (TTE) .  \nResults A total of 152 patients (53% male, 69 ± 12 years old, mean CHA2DS2-VASc score of 3 ±2) were analyzed, of which 80 had normal LAP (\u003C 12 mmHg) by direct measurement. Several ICE parameters were found to be significantly associated with mean LAP, including greater peak tricuspid regurgitation velocity (β = 3.5; p = 0.005) and average E/e′(β = 0.7; p \u003C 0.001) . In multivariable model, post-procedure intravenous diuretics were more commonly required in patients with abnormal diastolic function by ICE (mitral E/A OR = 8.1; average E/e′ OR = 24.2) .  \nConclusions ICE can be used to assess diastolic function with traditional parameters correlating with both TTE diastolic function and LAP. ICE measures of restrictive filling are associated with the need for post-procedural intravenous diuretics.  \nKeywords Atrial fibrillation · Diastolic function · Intracardiac echocardiography · Left atrial pressure · Transthoracic echocardiography · Outcome  \n􀀍 Timothy M. Markman [Timothy.Markman@pennmedicine.upenn.edu](Timothy.Markman@pennmedicine.upenn.edu)  \n1 Section for Electrophysiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA  \n2 Division of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA  \nAbbreviations  \nAF: Atrial fibrillation  \nASE: American Society of Echocardiography  \nICE: Intracardiac echocardiography  \nLA: Left atrium  \nLAP: Left atrial pressure  \nLV: Left ventricular  \nLVEF: Left ventricular ejection fraction  \nPVI: Pulmonary vein isolation  \nTTE: Transthoracic echocardiography  \n1 Introduction  \nDiastolic function has a complex, bidirectional relationship with atrial fibrillation (AF) . Abnormal diastolic function is associated with an increased risk for atrial fibrosis and AF. Conversely, the occurrence of AF can lead to further atrial fibrosis and diastolic dysfunction with elevation in left atrial pressure (LAP) [1, 2] and impaired atrial-ventricular coupling. Moreover, LAP may affect left atrial mechanical function through increased stretch and wall stress, resulting in progressive atrial remodeling in addition to symptoms of left sided volume and pressure overload [3–8] . Patients with both AF and diastolic dysfunction may be at higher risk of adverse cardiovascular","cbCaiqdKNJvC9TH8","https://ap.wps.com/l/cbCaiqdKNJvC9TH8","pdf",1315513,"English","# Introduction\n# Methods\n# Results\n# Conclusions\n# Abbreviations","[{\"question\":\"What clinical problem does the study address?\",\"answer\":\"It evaluates whether ICE can measure left ventricular diastolic function during atrial fibrillation ablation and whether these measurements reflect left atrial pressure and related outcomes.\"},{\"question\":\"How was left atrial pressure (LAP) defined in the study?\",\"answer\":\"Elevated LAP was defined as a direct measurement of ≥ 12 mmHg before atrial fibrillation ablation.\"},{\"question\":\"Which ICE-derived parameters were associated with higher LAP?\",\"answer\":\"Several parameters showed significant associations, including peak tricuspid regurgitation velocity and average E/e′.\"},{\"question\":\"What was the study’s conclusion about using ICE in AF ablation?\",\"answer\":\"ICE can assess diastolic function using traditional parameters that correlate with TTE diastolic function and LAP, and restrictive filling patterns were linked to the need for post-procedural intravenous diuretics.\"}]","Intracardiac echocardiography for left ventricular diastolic function assessment during atrial fibrillation ablation | PDF",1790652570,25]