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\nNATIONAL AUTISM  \nINTERAGENCY AUTISM COORDINATING COMMITTEE  \n2022  \nSUMMARY OF ADVANCES  \nin Autism Research  \nCOVER DESIGN  \nNIH Medical Arts Branch  \nCOPYRIGHT INFORMATION  \nAll material appearing in this report is in the public domain and may be reproduced or copied.  \nA suggested citation follows.  \nSUGGESTED CITATION  \nInteragency Autism Coordinating Committee (IACC). 2022 IACC Summary of Advances in Autism Research. December 2023. Retrieved from the U.S. Department of Health and Human Services Interagency Autism Coordinating Committee website: [https://iacc.hhs.gov/publications/summary-of-advances/2022/](https://iacc.hhs.gov/publications/summary-of-advances/2022/).  \nii  \nABOUT THE IACC  \nThe Interagency Autism Coordinating Committee (IACC) is a federal advisory committee charged with coordinating federal activities concerning autism spectrum disorder (ASD) and providing advice to the Secretary of Health and Human Services (HHS) on issues related to autism. The Committee was established by Congress under the Children's Health Act of 2000, reconstituted under the Combating Autism Act of 2006, and renewed most recently under the Autism Collaboration, Accountability, Research, Education, and Support (CARES) Act of 2019.  \nMembership of the Committee includes a wide array of federal agencies involved in autism research and services, as well as public stakeholders, including autistic adults, family members of those on the autism spectrum, advocates, service providers, and researchers, who represent a variety of perspectives. The IACC membership is composed to ensure that the Committee is equipped to address the broad range of issues and challenges experienced by individuals and families in the autism community.  \nUnder past and present authorizing legislation, the IACC was and is currently required to (1) develop and annually update a strategic plan for autism research,(2) develop and annually update a summary of advances in autism research, and (3) monitor federal activities related to autism.  \nThrough these and other activities, the IACC provides guidance to HHS and partners with other federal departments, research and advocacy organizations, and the broader autism community to accelerate research and enhance services with the goal of positively impacting the lives of people on the autism spectrum and their families.  \n***  \nFor more information about the IACC, see [http://www.iacc.hhs.gov](http://www.iacc.hhs.gov).  \niii  \nTABLE OF CONTENTS  \nINTRODUCTION  ........................................................................ VI  \nARTICLES SELECTED FOR THE 2022 SUMMARY OF ADVANCES  ............................ 1  \nSCREENING AND DIAGNOSIS  ........................................................... 3  \nClinician Diagnostic Certainty and the Role of the Autism Diagnostic Observation Schedule in Autism Spectrum Disorder Diagnosis in Young Children  ........................................ 4  \nA Data-Driven Approach in an Unbiased Sample Reveals Equivalent Sex Ratio of Autism Spectrum Disorder-Associated Impairment in Early Childhood  ............................ 6  \nProvider and Caregiver Satisfaction with Telehealth Evaluation of Autism Spectrum Disorder in Young Children During the COVID-19 Pandemic  ................................................ 7  \nEffectiveness of Screening in Early Intervention Settings to Improve Diagnosis of Autism and Reduce Health Disparities  ........................................................ 9  \nBIOLOGY  ............................................................................. 10  \nBroad transcriptomic dysregulation occurs across the cerebral cortex in ASD  ..................... 11  \nQuantifying social skill deficits and strengths profiles in autistic youth  .......................... 12  \nInfant Visual Brain Development and Inherited Genetic Liability in Autism  ....................... ","cbCaijRXGb02QpZB","https://ap.wps.com/l/cbCaijRXGb02QpZB","pdf",10288413,62,"English","# INTRODUCTION\n# ARTICLES SELECTED FOR THE 2022 SUMMARY OF ADVANCES\n# SCREENING AND DIAGNOSIS\n## Clinician Diagnostic Certainty and the Role of the Autism Diagnostic Observation Schedule in Autism Spectrum Disorder Diagnosis in Young Children\n## A Data-Driven Approach in an Unbiased Sample Reveals Equivalent Sex Ratio of Autism Spectrum Disorder-Associated Impairment in Early Childhood\n## Provider and Caregiver Satisfaction with Telehealth Evaluation of Autism Spectrum Disorder in Young Children During the COVID-19 Pandemic\n## Effectiveness of Screening in Early Intervention Settings to Improve Diagnosis of Autism and Reduce Health Disparities\n# BIOLOGY\n## Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD\n## Quantifying social skill deficits and strengths profiles in autistic youth\n## Infant Visual Brain Development and Inherited Genetic Liability in Autism\n## Mapping the time course of overt emotion dysregulation, self-injurious behavior, and aggression in psychiatrically hospitalized autistic youth: A naturalistic study\n## Predictors of language regression and its association with subsequent communication development in children with autism\n# GENETIC AND ENVIRONMENTAL FACTORS\n## Associations Between Pregnancy-Related Predisposing Factors for Offspring Neurodevelopmental Conditions and Parental Genetic Liability to Attention-Deficit/Hyperactivity Disorder, Autism, and Schizophrenia: The Norwegian Mother, Father and Child Cohort Study (MoBa)\n# INTERVENTIONS\n## Super responders: Predicting language gains from JASPER among limited language children with autism spectrum disorder\n# SERVICES AND SUPPORTS\n## Disparities in Early Intervention Program Participation by Children With Autism Spectrum Disorder in a US Metropolitan Area, 2006 to 2016\n## Mental health screening in pediatric primary care for children with autism\n# LIFESPAN\n## Barriers to healthcare and self-reported adverse outcomes for autistic adults: a cross-sectional study\n## How do autistic people fare in adult life and can we predict it from childhood?\n## Associations between co-occurring conditions and age of autism diagnosis: Implications for mental health training and adult autism research\n## Vocational Outcome","[{\"question\":\"What is the purpose of the IACC 2022 Summary of Advances in Autism Research?\",\"answer\":\"It compiles progress in autism research and organizes selected advances across key research areas, supporting coordination of federal activities related to autism spectrum disorder.\"},{\"question\":\"Which topics are covered in the 2022 summary?\",\"answer\":\"The report groups selected articles into screening and diagnosis, biology, genetic and environmental factors, interventions, services and supports, and lifespan outcomes.\"},{\"question\":\"How does the report connect committee responsibilities to ongoing work in autism research?\",\"answer\":\"The IACC is required to maintain and annually update a strategic plan, develop and annually update a summary of advances, and monitor federal autism-related activities to guide HHS and partners.\"}]","INTERAGENCY AUTISM COORDINATING COMMITTEE - 2022 - Summary of Advances in Autism Research | PDF",1792052920,156]