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is the role of the Interagency Autism Coordinating Committee (IACC) in ASD research and policy?","Question",{"text":62,"@type":63},"The IACC is a federal advisory committee that coordinates federal activities concerning autism spectrum disorder and provides advice to the Secretary of Health and Human Services on autism-related issues.","Answer",{"name":65,"@type":60,"acceptedAnswer":66},"What responsibilities does the IACC have under the Children’s Health Act and subsequent reauthorizations?",{"text":67,"@type":63},"Under the Combating Autism Act and later reauthorizations, the IACC must develop and annually update a strategic plan for ASD research, develop and annually update a summary of advances in ASD research, and monitor federal ASD-related activities.",{"name":69,"@type":60,"acceptedAnswer":70},"How does the 2018 summary organize research advances?",{"text":71,"@type":63},"The summary selects articles under six guiding questions, covering early detection, underlying biology, 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Disorder Research  \nINTERAGENCY AUTISM COORDINATING COMMITTEE  \n2018  \nSUMMARY OF ADVANCES  \nIn Autism Spectrum Disorder Research  \nCOVER DESIGN  \nNIH Medical Arts Branch  \nCOPYRIGHT INFORMATION  \nThis report is a Work of the United States Government. A suggested citation follows.  \nSUGGESTED CITATION  \nInteragency Autism Coordinating Committee (IACC). 2018 IACC Summary of Advances in Autism Spectrum Disorder Research. April 2019. Retrieved from the U.S. Department of Health and Human Services Interagency Autism Coordinating Committee website: [https://iacc.hhs.gov/publications/summary-of-advances/2018/](https://iacc.hhs.gov/publications/summary-of-advances/2018/).  \niii  \nABOUT THE IACC  \nThe Interagency Autism Coordinating Committee (IACC) is a federal advisory committee charged with coordinating Federal activities concerning autism spectrum disorder (ASD) and providing advice to the Secretary of Health and Human Services (HHS) on issues related to autism. The Committee was established by Congress under the Children's Health Act of 2000, reconstituted under the Combating Autism Act (CAA) of 2006, and renewed most recently under the Autism Collaboration, Accountability, Research, Education, and Support (CARES) Act of 2014.  \nMembership of the Committee includes a wide array of federal agencies involved in ASD research and services, as well as public stakeholders, including self-advocates, family members of children and adults with ASD, advocates, service providers, and researchers, who represent a variety of perspectives from within the autism community. The IACC membership is composed to ensure that the Committee is equipped to address the wide range of issues and challenges faced by individuals and families affected by autism.  \nUnder the CAA and subsequent reauthorizations, the IACC is required to (1) develop and annually update a strategic plan for ASD research,(2) develop and annually update a summary of advances in ASD research, and (3) monitor federal activities related to ASD.  \nThrough these and other activities, the IACC provides guidance to HHS and partners with other federal departments, federal agencies, research and advocacy organizations, and the broader autism community to accelerate research and enhance services with the goal of profoundly improving the lives of people with ASD and their families.  \n***  \nFor more information about the IACC, see [http://www.iacc.hhs.gov](http://www.iacc.hhs.gov).  \niv  \nTABLE OF CONTENTS  \nINTRODUCTION  ........................................................................ VI  \nARTICLES SELECTED FOR THE 2018 SUMMARY OF ADVANCES  ............................ 1  \nQUESTION 1: HOW CAN I RECOGNIZE THE SIGNS OF ASD, AND WHY IS EARLY DETECTION SO IMPORTANT?  ............................................................3  \nEEG Analytics for Early Detection of Autism Spectrum Disorder: A data-driven approach........... 3  \nAutomatic Emotion and Attention Analysis of Young Children at Home: A ResearchKit Autism Feasibility Study....................................................................... 5  \nA longitudinal study of parent-reported sensory responsiveness in toddlers at-risk for autism........ 6  \nQUESTION 2: WHAT IS THE BIOLOGY UNDERLYING ASD?  .................................7  \nNeuron numbers increase in the human amygdala from birth to adulthood, but not in autism........7  \nComplete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons..................................... 8  \nSocial deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition.................................................................. 9  \nQUESTION 3: WHAT CAUSES ASD, AND CAN DISABLING ASPECTS OF ASD BE PREVENTED OR PREEMPTED?  .......................................................... 11","cbCaimLecfYZz4XN","https://ap.wps.com/l/cbCaimLecfYZz4XN","pdf",1624003,49,"English","# Introduction\n# Articles Selected for the 2018 Summary of Advances\n# Question 1: How can I recognize the signs of ASD, and why is early detection so important?\n## EEG Analytics for Early Detection of Autism Spectrum Disorder: A data-driven approach\n## Automatic Emotion and Attention Analysis of Young Children at Home: A ResearchKit Autism Feasibility Study\n## A longitudinal study of parent-reported sensory responsiveness in toddlers at-risk for autism\n# Question 2: What is the biology underlying ASD?\n## Neuron numbers increase in the human amygdala from birth to adulthood, but not in autism\n## Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons\n## Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition\n# Question 3: What causes ASD, and can disabling aspects of ASD be prevented or preempted?\n## Analysis of shared heritability in common disorders of the brain\n## Paternally inherited cis-regulatory structural variants are associated with autism\n## Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap\n# Question 4: Which treatments and interventions will help?\n## Cluster randomized trial of the classroom SCERTS intervention for elementary students with autism spectrum disorder\n## Meta-analysis of parent-mediated interventions for young children with autism spectrum disorder\n## Are Children Severely Affected by Autism Spectrum Disorder Underrepresented in Treatment Studies? An Analysis of the Literature\n# Question 5: What kinds of services and supports are needed to maximize quality of life for people on the autism spectrum?\n## Effects of State Autism Mandate Age Caps on Health Service Use and Spending Among Adolescents\n## Vaccination Patterns in Children After Autism Spectrum Disorder Diagnosis and in Their Younger Siblings\n# Question 6: How can we meet the needs of people with ASD as they progress into and through adulthood?\n## Autism spectrum disorder symptoms from ages 2 to 19 years: Implications for diagnosing adolescents and young adults\n## Psychiatric and Medical Conditions in Transition-Aged Individuals With ASD","[{\"question\":\"What is the role of the Interagency Autism Coordinating Committee (IACC) in ASD research and policy?\",\"answer\":\"The IACC is a federal advisory committee that coordinates federal activities concerning autism spectrum disorder and provides advice to the Secretary of Health and Human Services on autism-related issues.\"},{\"question\":\"What responsibilities does the IACC have under the Children’s Health Act and subsequent reauthorizations?\",\"answer\":\"Under the Combating Autism Act and later reauthorizations, the IACC must develop and annually update a strategic plan for ASD research, develop and annually update a summary of advances in ASD research, and monitor federal ASD-related activities.\"},{\"question\":\"How does the 2018 summary organize research advances?\",\"answer\":\"The summary selects articles under six guiding questions, covering early detection, underlying biology, causes and prevention, treatments, services and supports for quality of life, and needs as individuals transition into and through adulthood.\"}]","Interagency Autism Coordinating Committee - 2018 Summary of Advances in Autism Spectrum Disorder Research | PDF",1792051292,123]