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A retrospective cohort study included congestive heart failure (CHF) patients presenting to the emergency department with a primary CHF diagnosis. Patients who interacted with SMS nudges showed 19% higher odds of filling prescriptions overall and 6% lower odds of readmission versus non-interacting patients. Interactive SMS nudges delivered via a novel tool may improve prescription fill rates across multiple CHF groups and reduce readmissions.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/interaction-with-sms-text-reminders-correlate-with-improved-medication-adherence-and-readmission-rates-for-congestive-heart-failure-patients-a-retrospective-cohort-study/408521/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/interaction-with-sms-text-reminders-correlate-with-improved-medication-adherence-and-readmission-rates-for-congestive-heart-failure-patients-a-retrospective-cohort-study/408521.png","ImageObject",300,407,{"name":92,"@type":93},"mieayamfan","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-02","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"How were SMS text-reminders evaluated in the study?","Question",{"text":112,"@type":113},"The study compared CHF patients who did and did not interact with SMS nudges using a retrospective cohort design, then matched patients with prescription fill records after hospitalization.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What effect did interacting with SMS nudges have on prescription filling?",{"text":117,"@type":113},"Patients who interacted with SMS nudges had 19% higher odds of filling prescriptions overall.",{"name":119,"@type":110,"acceptedAnswer":120},"Did interacting with SMS nudges affect hospital readmissions?",{"text":121,"@type":113},"Yes. Interacting patients had 6% lower odds of being readmitted to the hospital than non-interacting patients.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},408521,1790763681,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},962090893677,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","OPEN ACCESS  \nCitation: Long B, Davis B, McPheters R, Burton S, Hamoud N, Garmat D, et al. (2025) Interaction with SMS text-reminders correlate with improved medication adherence andreadmission rates for congestive heart failure patients: A retrospective cohort study. PLOS Digit Health 4(12): e0001157. [https://doi](https://doi). org/10.1371/journal.pdig.0001157  \nEditor: Simon Reif, ZEW-Leibniz Centre for European Economic Research: ZEW-LeibnizZentrum fur Europaische Wirtschaftsforschung GmbH Mannheim, GERMANY  \nReceived: January 20, 2025  \nAccepted: December 8, 2025  \nPublished: December 31, 2025  \nCopyright: © 2025 Long et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.  \nData availability statement: The data underlying this study contain Protected Health Information (PHI) and cannot be  \nRESEARCH ARTICLE  \nInteraction with SMS text-reminders correlate with improved medication adherence andreadmission rates for congestive heart failure patients: A retrospective cohort study  \nBen Long1☯, Brian Davis1☯, Rebekah McPheters1☯, Steven Burton1☯, Nabeel Hamoud2‡, Dan Garmat2‡, Suzanne Catalfomo2‡, Fei Li2‡, Ying Zhou2‡, Yan L. Zhuang2‡,  \nColin A. Banas2‡, Weston W. Blakeslee2‡*  \n1 Department of Internal Medicine, Magnolia Regional Health Center, Corinth, Mississippi, United States of America, 2 Department of Applied Clinical Research, DrFirst, Rockville, Maryland, United States of America  \n☯ These authors contributed equally to this work.  \n‡ These authors contributed equally to this work.  \n* [wblakeslee@drfirst.com](wblakeslee@drfirst.com)  \nAbstract  \nShort message service text reminders (SMS nudges) aimed to help vulnerable patient populations remember to fill their prescriptions are becoming more common but accurately measuring their effects on improving prescription fill and readmission rates remains challenging. Patients who presented to the emergency department (ED) with a primary diagnosis of congestive heart failure (CHF) were included in the study. We conducted a retrospective cohort study of CHF patients who did and did not interact with SMS nudges, then matched patients who were prescribed medications at any point in their hospital visit with records of subsequent prescription fills. Patients that interacted with SMS nudges had 19% higher odds of filling prescriptions overall (1 .19 OR (95% CI: 1.15 – 1.24), p \u003C 0.001) and 6% lower odds of being readmitted to the hospital (0 .94 (95% CI: 0.9 – 0.99), p = 0.009) than patients who did not interact with SMS nudges. Interactive SMS nudges via a novel tool may improve prescription fill rates across multiple groups of CHF patients, and contribute to a reduction in readmissions.  \nAuthor summary  \nWhen patients leave the hospital with new prescriptions, many never fill them. A problem that can lead to worsening symptoms and costly hospital readmissions. We wanted to investigate if personalized text message reminders could help patients remember to pick up their medications after being hospitalized for heart failure. We studied over 1,200 heart failure patients at a rural hospital who received  \nPLOS Digital Health | [https://doi.org/10.1371/journal.pdig.0001157](https://doi.org/10.1371/journal.pdig.0001157) December 31, 2025 1 / 14  \nshared publicly for ethical and legal reasons. A Business Associates Agreement (BAA) is in place between the two collaborating organizations for the protection and exchange of PHI to comply with HIPAA and NIST standards. Making these data publicly available enables the chance to compromise patient privacy. In our analysis, linking readmission data, electronic prescribing data, medication history data, and text message engagement data to unique patients were essential for the accuracy of our findings. A reader of our study may make a reasonable request to","cbCaihmxegDo2VhA","https://ap.wps.com/l/cbCaihmxegDo2VhA","pdf",951778,14,"English","# Abstract\n## Study design and population\n## Key outcomes: prescription fills and readmissions\n## Interpretation and implications","[{\"question\":\"How were SMS text-reminders evaluated in the study?\",\"answer\":\"The study compared CHF patients who did and did not interact with SMS nudges using a retrospective cohort design, then matched patients with prescription fill records after hospitalization.\"},{\"question\":\"What effect did interacting with SMS nudges have on prescription filling?\",\"answer\":\"Patients who interacted with SMS nudges had 19% higher odds of filling prescriptions overall.\"},{\"question\":\"Did interacting with SMS nudges affect hospital readmissions?\",\"answer\":\"Yes. Interacting patients had 6% lower odds of being readmitted to the hospital than non-interacting patients.\"}]","Interaction with SMS Text-Reminders Correlate with Improved Medication Adherence and Readmission Rates for Congestive Heart Failure Patients - A Retrospective Cohort Study | PDF",1790579652,35]