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A middle-aged male presented with a painful, discharging polypoidal infraauricular mass initially misdiagnosed as a dermoid cyst based on imaging and biopsy. Wide local excision with bilobed flap reconstruction was performed. Histopathology confirmed myxoma, and at six months the patient showed excellent wound healing and functional recovery, highlighting the need for myxoma consideration in neck mass differential diagnoses.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/infra-auricular-subcutaneous-myxoma-surgical-challenges-and-histopathological-insights/454905/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/infra-auricular-subcutaneous-myxoma-surgical-challenges-and-histopathological-insights/454905.png","ImageObject",300,407,{"name":92,"@type":93},"eBook King","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":19},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why was the infraauricular myxoma initially misdiagnosed?","Question",{"text":112,"@type":113},"Imaging and initial biopsy suggested a dermoid cyst with secondary inflammation, creating a diagnostic ambiguity for infraauricular masses.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What surgical approach was used for reconstruction after excision?",{"text":117,"@type":113},"The defect after wide local excision was reconstructed using a bilobed flap to cover the infraauricular soft-tissue defect.",{"name":119,"@type":110,"acceptedAnswer":120},"What confirmed the diagnosis and how did the patient do after surgery?",{"text":121,"@type":113},"Histopathological analysis confirmed myxoma. 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Composed of stellate cells in a mucoid matrix, their incidence in intramuscular locations is about 1 in 1,000,000, with fewer than 200 cases reported since 1948. This report discusses the surgical treatment and pathology of a subcutaneous myxoma in the infraauricular region.  \nCase Report:  \nA middle-aged male presented with a painful, discharging polypoidal mass in the infraauricular area, initially misdiagnosed as a dermoid cyst from imaging and biopsy. Surgical excision and reconstruction using a bilobed flap were performed. Histopathological analysis confirmed myxoma. At the six-month follow-up, the patient demonstrated excellent wound healing and functional recovery, emphasizing the effectiveness of the bilobed flap in infraauricular reconstruction.  \nConclusion:  \nThis case highlights the diagnostic challenge of myxomas, especially in unusual locations. Effective management relies on surgical removal with histological confirmation, demonstrating the importance of considering myxomas in differential diagnoses of neck masses. The successful use of a bilobed flap for reconstruction emphasizes the necessity for appropriate surgical planning to manage aesthetic and functional outcomes.  \nKeywords: Neoplasms, Mesenchymal, Connective Tissue, Reconstructive Surgical Procedures, Fibroblasts  \nReceived date:9 Jun 2024  \nAccepted date: 7 Jul 2025  \n*Please cite this article; Yadav S, Gupta A. Infra-Auricular Subcutaneous Myxoma: Surgical Challenges and  \nHistopathological Insights. Iran J Otorhinolaryngol. 2025:37(6):353-357. Doi:10.22038/ijorl.2025.80373.3704 1Department of ENT & Head Neck Surgery, UPUMS-Saifai, Uttar Pradesh, India.  \n2Department of General surgery, Dr B.R. Ambedkar Institute of Medical Sciences, Mohali, Punjab, India.  \n*Corresponding author:  \nDepartment of ENT & Head Neck Surgery, UPUMS-Saifai, Uttar Pradesh, [India. E-mail: syadav1704@gmail.com](India. E-mail: syadav1704@gmail.com)  \nIntroduction  \nMyxomas are benign, locally invasive mesenchymal neoplasms composed of undifferentiated stellate cells embedded in amucoid stroma. They are rare and seldom occur in the neck region. Overall incidence of intramuscular myxoma is estimated to be 1 in 1,000,000 (1) . Since the establishment of diagnostic criteria in 1948, fewer than 200 reported cases of myxomas in the head and neck have been reported (1) . This case report highlights the clinical features, surgical management, and histopathological findings of an infraauricular subcutaneous myxoma. On imaging and initial biopsy, differentials such asdermoid cyst, epidermoid cyst, and neurofibroma were considered, which highlights the diagnostic ambiguity often encountered with infraauricular masses. The uniqueness of this case lies in its uncommon location.  \nCase Report  \nA middle-aged male patient presented with apolypoidal mass on the left side of his neck that had developed over 3-4 months. The patient complains of discharge over the swelling and occasional pain. There was no history of trauma, fever, dysphagia, hoarseness, weight loss and no other remarkable medical or family history. Clinical examination revealed a firm, non-mobile fungating mass in the infraauricular region posterior to mandibular ramus measuring 3x3 cm (Fig. 1) .  \nFig. 1: Patient observed in the outpatient department with a polypoidal mass located in the infraauricular region, alongside discharge surrounding the area  \nThere was no other significantlymphadenopathy. Examination of oral cavity, oropharynx, nasopharynx, ear examination was  \nnormal. All cranial nerves were intact and symmetric. Contrast enhanced computed tomography of neck showed 4 cm mass at the level C5-C6, lateral to trapezius in subcutaneous plane. A ","cbCaiecTJved90Uk","https://ap.wps.com/l/cbCaiecTJved90Uk","pdf",962656,"English","# Abstract\n# Introduction\n# Case Report\n## Clinical Presentation\n## Imaging and Biopsy\n## Surgical Excision and Reconstruction\n## Postoperative Course\n# Histopathological Findings\n# Conclusion","[{\"question\":\"Why was the infraauricular myxoma initially misdiagnosed?\",\"answer\":\"Imaging and initial biopsy suggested a dermoid cyst with secondary inflammation, creating a diagnostic ambiguity for infraauricular masses.\"},{\"question\":\"What surgical approach was used for reconstruction after excision?\",\"answer\":\"The defect after wide local excision was reconstructed using a bilobed flap to cover the infraauricular soft-tissue defect.\"},{\"question\":\"What confirmed the diagnosis and how did the patient do after surgery?\",\"answer\":\"Histopathological analysis confirmed myxoma. At six-month follow-up, the patient demonstrated excellent wound healing and functional recovery.\"}]","Infra-Auricular Subcutaneous Myxoma: Surgical Challenges and Histopathological Insights | PDF",1790741686,13]