[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-459956-105":59,"doc-detail-459956-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","inflammatory-myofibroblastic-tumor-on-second-portion-of-duodenum-a-case-report","Inflammatory myofibroblastic tumor on second portion of duodenum - a case report","","Inflammatory myofibroblastic tumors (IMTs) in the duodenum are rare, with epidemiologic and clinical patterns limited by few reported cases. This manuscript provides subsequent long-term follow-up for a previously reported adult case, extending postoperative observation to 88 months and adding radiologic and pathologic findings beyond the earlier report. The report emphasizes long-term benign tumor behavior despite positive surgical margins and ALK-negative immunohistochemistry, offering clinically meaningful evidence to the scarce adult duodenal IMT literature.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/inflammatory-myofibroblastic-tumor-on-second-portion-of-duodenum-a-case-report/459956/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/inflammatory-myofibroblastic-tumor-on-second-portion-of-duodenum-a-case-report/459956.png","ImageObject",300,407,{"name":92,"@type":93},"Grenda","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-07","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":19},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why are duodenal inflammatory myofibroblastic tumors considered difficult to characterize clinically?","Question",{"text":112,"@type":113},"Their epidemiologic and clinical features remain poorly defined because of the limited number of reported cases.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What is the main purpose of this manuscript?",{"text":117,"@type":113},"To provide an extended long-term follow-up of the same patient previously reported in 2018, including additional radiologic and pathologic details.",{"name":119,"@type":110,"acceptedAnswer":120},"What follow-up duration is reported for the postoperative course?",{"text":121,"@type":113},"An 88-month postoperative course is described.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},459956,1790757351,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":19,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":129,"read_time":143,"preview_page_count":4},7971474921005,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","Korean Journal of Clinical Oncology 2025;21:159-163 [https://doi.org/10.14216/kjco.25374](https://doi.org/10.14216/kjco.25374)  \n[pISSN 1738-8082](pISSN 1738-8082) ∙ eISSN 2288-4084  \nCase Report  \nInflammatory myofibroblastic tumor on second portion of duodenum: a case report  \nMyeong Hun Oh1, Hyung Il Seo1, Kyung Un Choi2, Seung Baek Hong3,Young Mok Park1, Byeong Gwan Noh1, Su Bin Song1  \n1Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Busan, Korea 2Department of Pathology, Pusan National University School of Medicine, Yangsan, Korea 3Department of Radiology, Pusan National University School of Medicine, Yangsan, Korea  \nInflammatory myofibroblastic tumors (IMTs) of the duodenum are exceptionally uncommon, and their epidemiologic and clinical characteristics remain poorly defined because of the limited number of reported cases. We previously reported a case of duodenal IMT in the Korean Journal of Gastroenterology in 2018, with follow-up data available only up to 12 months. IMTs typically behave in a benign manner, but they may occasionally demonstrate local invasiveness and recurrence; therefore, achieving complete surgical excision is crucial, followed by long-term surveillance. In the present manuscript, we provide a subsequent long-term follow-up report of the same patient, offering an extended 88-month postoperative course and additional radiologic and pathologic details not included in the earlier publication. This follow-up report highlights the long-term benign behavior of the tumor despite positive surgical margins and anaplastic lymphoma kinase (ALK)-negative immunohistochemistry, contributing meaningful information to the scarce literature on adult duodenal IMTs.  \nKeywords: Duodenum, Neoplasms, Soft tissue neoplasms, Case reports  \nINTRODUCTION  \nInflammatory myofibroblastic tumors (IMTs) are uncommon mesenchymal neoplasms defined by the proliferation of myofibroblastic spindle cells accompanied by a variable inflammatory infiltrate composed mainly of plasma cells, lymphocytes, and eosinophils [1]. These tumors may develop in a wide range of anatomic sites that contain mucosal or serosal surfaces, including the respiratory, gastrointestinal, and genitourinary tracts, as well as the orbit and oral cavity. IMTs tend to occur predominantly in children and young adults and often appear as intra-abdominal masses involving the gastrointestinal tract. While most IMTs behave in an indolent manner, local recurrence occurs in up to one-quarter of cases, and distant metastasis, though rare ( \u003C 5%), has been described in the lung, brain, liver, and bone [2-4]. In the United States, approxi-  \nReceived: Sep 12, 2025 Revised: Nov 30, 2025 Accepted: Dec 16, 2025  \nCorrespondence to: Hyung Il Seo  \nDepartment of Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, 179 Gudeok-ro, Seo-gu, Busan 49241, Korea  \nTel: +82-51-240-7238, Fax: +82-51-247-1365  \n[E-mail:](E-mail: seohi71@hanmail.net)[ seohi71@hanmail.net](E-mail: seohi71@hanmail.net)  \n© 2025 Korean Society of Surgical Oncology  \nThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ([http://creativecommons.org/licenses/by-nc/4.0](http://creativecommons.org/licenses/by-nc/4.0)) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.  \nmately 150 to 200 new cases are reported annually, and the overall epidemiologic profile ofIMTs remains insufficiently characterized [5]. Clinically, patients with IMT often present with nonspecific manifestations, including abdominal pain, a palpable mass, or symptoms related to gastrointestinal obstruction. Systemic findings such as fever, weight loss, night sweats, and general malaise may also be observed. Immunohistochemically, the neoplastic cells typically express vimentin and show ","cbCaidXGR25vDXbl","https://ap.wps.com/l/cbCaidXGR25vDXbl","pdf",977248,"English","# Introduction\n# Case report","[{\"question\":\"Why are duodenal inflammatory myofibroblastic tumors considered difficult to characterize clinically?\",\"answer\":\"Their epidemiologic and clinical features remain poorly defined because of the limited number of reported cases.\"},{\"question\":\"What is the main purpose of this manuscript?\",\"answer\":\"To provide an extended long-term follow-up of the same patient previously reported in 2018, including additional radiologic and pathologic details.\"},{\"question\":\"What follow-up duration is reported for the postoperative course?\",\"answer\":\"An 88-month postoperative course is described.\"}]","Inflammatory myofibroblastic tumor on second portion of duodenum - a case report | PDF",13]