[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-356139-105":59,"doc-detail-356139-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","imaging-diagnosis-of-cystic-intraparenchymal-brain-neoplasms","Imaging diagnosis of cystic intraparenchymal brain neoplasms","","Certain brain tumors contain cystic components, and MRI proves especially effective for evaluating the location, enhancement behavior, and morphology of cystic regions. The resulting imaging patterns help radiologists narrow differential diagnoses, since cystic components often accompany circumscribed, relatively lower-grade tumors and may correlate with favorable outcomes. High-grade neoplasms such as glioblastoma can also show cystic changes. This review summarizes representative intraparenchymal cystic tumor entities and provides MRI features to support differentiation and clinical management.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/imaging-diagnosis-of-cystic-intraparenchymal-brain-neoplasms/356139/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/imaging-diagnosis-of-cystic-intraparenchymal-brain-neoplasms/356139.png","ImageObject",300,407,{"name":92,"@type":93},"LangkahRina","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-23","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why is MRI important for diagnosing cystic intraparenchymal brain tumors?","Question",{"text":112,"@type":113},"MRI helps characterize the cystic regions by assessing location, enhancement, and morphology, enabling radiologists to narrow the differential diagnosis.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which tumor types commonly show cystic components?",{"text":117,"@type":113},"Cystic components are frequently seen in certain low-grade neoplasms such as pilocytic astrocytoma and glioneuronal tumors, while high-grade tumors like glioblastoma can occasionally exhibit cystic changes.",{"name":119,"@type":110,"acceptedAnswer":120},"How does this review support clinical management?",{"text":121,"@type":113},"It summarizes representative cystic intraparenchymal neoplasms and highlights MRI features that facilitate tumor differentiation, helping guide appropriate clinical decision-making.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},356139,1791102777,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},962090893776,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Japanese Journal of Radiology (2026) 44:1519–1533 [https://doi.org/10.1007/s1](https://doi.org/10.1007/s1) 1604-026-02001-w  \nINVITED REVIEW  \nImaging diagnosis of cystic intraparenchymal brain neoplasms  \nSonoko Oshima1,2 · Yasutaka Fushimi1,3 · Sachi Okuchi1 · Satoshi Nakajima1 · Akihiko Sakata1 · Takayuki Yamamoto1 · Yuji Nakamoto1 · Noriko Salamon2  \nReceived: 6 March 2026 / Accepted: 20 April 2026 / Published online: 30 May 2026 © The Author(s) 2026  \nAbstract  \nCertain brain tumors exhibit cystic components. MRI is particularly effective in characterizing the location, enhancement, and morphology of these cystic regions, enabling radiologists to narrow the differential diagnosis. Cystic components are often associated with circumscribed tumors and may be linked to favorable outcomes. High-grade tumors such as glioblastoma can also occasionally exhibit cystic components. Here, we summarize the imaging characteristics of representative cystic brain intraparenchymal neoplasms, including hemangioblastoma, pilocytic astrocytoma, pleomorphic xanthoastrocytoma, ganglioglioma, desmoplastic infantile ganglioglioma/astrocytoma, central neurocytoma, dysembryoplastic neuroepithelial tumor, ependymoma, glioblastoma, and metastases. This review aims to provide MRI features that facilitate differentiation of these tumors and support appropriate clinical management.  \nKeywords Central nervous system · Intraparenchymal tumor · Cystic brain lesion · Magnetic resonance imaging  \nIntroduction  \nCertain brain tumors demonstrate cystic components either within the tumor mass or as surrounding fluid-filled compartments. Accurate radiologic evaluation provides detailed insights into cystic and solid components, and specific imaging patterns can help narrow the differential diagnosis. Cystic components are commonly observed in certain low-grade neoplasms such as pilocytic astrocytoma (PA) and glioneuronal tumors, in association with an expansive, well-circumscribed growth pattern. High-grade tumors such as glioblastoma may also exhibit cystic components.  \nThis review provides a comprehensive overview of both conventional and advanced MR imaging characteristics  \n􀀍 Sonoko Oshima [soshima@kuhp.kyoto-u.ac.jp](soshima@kuhp.kyoto-u.ac.jp)  \n1 Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan  \n2 Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA  \n3 Biomedical Imaging Research Center, University of Fukui, Fukui, Japan  \nof intraparenchymal brain neoplasms that typically contain cystic components, as classified according to the 2021 WHO criteria. These include lesions presenting as cysts with mural nodules, such as hemangioblastoma (HB), PA, pleomorphic xanthoastrocytoma (PXA), ganglioglioma, and desmoplastic infantile ganglioglioma/astrocytoma (DIG/DIA) . Multiloculated or “soap-bubble-like” tumors, including dysembryoplastic neuroepithelial tumor (DNET) and central neurocytoma, are also discussed. In addition, ependymoma, which often demonstrates a solid mass with cystic components, is reviewed. Finally, tumors characterized by irregular cystic or necrotic changes, such as glioblastoma and brain metastasis, are included (Table 1). Although other glioneuronal tumors, such as papillary glioneuronal tumor, rosette-forming glioneuronal tumor, and myxoid glioneuronal tumor, can also present with cystic components, these relatively rare entities are beyond the scope of this review. By highlighting key imaging features of these lesions, this article aims to assist radiologists in making more accurate interpretations and to support informed clinical decision-making.  \nTable 1 Clinical and Imaging characteristics of cystic brain tumors  \n\n| Morphologic pattern | Tumor type | Typical age group | Common location | Enhancement pattern | Other imag\u003Cbr>ing features (including DWI/PWI) |\n| --- | --- | --- | --- | --- | --","cbCaipxxvRg2Sbgx","https://ap.wps.com/l/cbCaipxxvRg2Sbgx","pdf",1631937,15,"English","# Abstract\n# Introduction\n# Imaging characteristics of cystic intraparenchymal brain neoplasms\n## Morphologic patterns and representative tumor types\n## Table 1: Clinical and imaging characteristics","[{\"question\":\"Why is MRI important for diagnosing cystic intraparenchymal brain tumors?\",\"answer\":\"MRI helps characterize the cystic regions by assessing location, enhancement, and morphology, enabling radiologists to narrow the differential diagnosis.\"},{\"question\":\"Which tumor types commonly show cystic components?\",\"answer\":\"Cystic components are frequently seen in certain low-grade neoplasms such as pilocytic astrocytoma and glioneuronal tumors, while high-grade tumors like glioblastoma can occasionally exhibit cystic changes.\"},{\"question\":\"How does this review support clinical management?\",\"answer\":\"It summarizes representative cystic intraparenchymal neoplasms and highlights MRI features that facilitate tumor differentiation, helping guide appropriate clinical decision-making.\"}]","Imaging diagnosis of cystic intraparenchymal brain neoplasms | PDF",1790123596,38]