[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-381323-105":59,"doc-detail-381323-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","identifying-the-cause-of-acute-left-sided-visual-loss-a-clinical-dilemma","Identifying the Cause of Acute Left-Sided Visual Loss - A Clinical Dilemma","","Given rising incidence of head and neck cancers over the past decade, chemoradiation use has increased, yet clear guidance for long-term surveillance and screening remains limited. This case report describes acute left eye blindness in a veteran with prior laryngeal cancer treated with chemoradiation and on anticoagulation for a left ventricular thrombus. The competing risks create a diagnostic challenge for determining etiology. The case underscores the value of thorough patient-centered annual evaluation to enable early noninvasive or minimally invasive intervention.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/identifying-the-cause-of-acute-left-sided-visual-loss-a-clinical-dilemma/381323/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/identifying-the-cause-of-acute-left-sided-visual-loss-a-clinical-dilemma/381323.png","ImageObject",300,407,{"name":92,"@type":93},"\tCallum ","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-24","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":19},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What does the case report focus on regarding acute left-sided visual loss?","Question",{"text":112,"@type":113},"It focuses on identifying the cause of sudden acute left eye blindness in a patient with prior laryngeal cancer treated with chemoradiation and concurrent anticoagulation-related diagnostic complexity.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which patient history and clinical context contribute to the diagnostic challenge?",{"text":117,"@type":113},"The patient’s history includes laryngeal cancer status post chemoradiation and anticoagulation for a left ventricular thrombus, both of which can influence vascular and thrombotic etiologies.",{"name":119,"@type":110,"acceptedAnswer":120},"How were the potential causes evaluated in the investigations and diagnosis?",{"text":121,"@type":113},"Investigations included neuroimaging with CT, CTA, and MRI, and the diagnosis relied on imaging findings such as vascular occlusions and chronic infarcts.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},381323,1791007020,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":19,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":19,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":52},137451211410,"https://ap-avatar.wpscdn.com/avatar/2000bb0a9246f588df?x-image-process=image/resize,m_fixed,w_180,h_180&k=1786362646172706240","Case Report J Med Cases. 2023;14(6):200-203  \nIdentifying the Cause of Acute Left-Sided Visual Loss:  \nA Clinical Dilemma  \nAnirudh R. Damughatlaa, b, c, g, Vanessa Milan-Ortiza, b, Pragna Koletid, Myrna M. Milan-Ortize, Sudhir Reddy Pashamf, Abhishek R. Damughatlac, Saivaishnavi Kamathama, b,  \nKareem Bazzya, b  \nAbstract  \nGiven the global increase in the incidence of head and neck cancers over the last decade, the use of chemoradiation has also increased. It is well known that chemotherapy/radiation are established standard therapies in head and neck cancers, especially in patients who are not candidates for surgery. Despite this increase in chemoradiation therapies in head and neck cancers, there is a lack of established guidelines on the surveillance and screening of these patients for long-term complications. We present an interesting case of acute left eye blindness in a veteran patient with a history of laryngeal cancer status post chemoradiation and in the setting of a left ventricular (LV) thrombuson anticoagulation resulting in a diagnostic challenge determining the etiology. This case emphasizes the need for thorough patient-centered annual evaluation, thus providing an opportunity for early noninvasive or minimally invasive intervention.  \nKeywords: Acute left eye blindness; Laryngeal cancer status post chemoradiation; LV thrombus; Large vessel; Carotid stenosis; Stenosis due to chemoradiation  \nIntroduction  \nLaryngeal cancer is one of the most common cancers of the  \nManuscript submitted April 17, 2023, accepted June 5, 2023 Published online xx xx, 2023  \naDepartment of Internal Medicine, Wayne State University & Detroit Medical Center, Detroit, MI, USA  \nbDepartment of Internal Medicine, John D. Dingell Veterans Affairs Medical Center, Detroit, MI, USA  \ncDepartment of Biomedical Engineering, The Ohio State University, Columbus, OH, USA  \ndDepartment of Internal Medicine, Suburban Community Hospital, Norristown, PA, USA  \neTransitional Program, Metropolitan Hospital Dr. Pila, Ponce, Puerto Rico fDepartment of Internal Medicine, Guthrie Robert Packer Hospital, Sayre, PA, USA  \ngCorresponding Author: Anirudh R. Damughatla, Department of Internal Medicine, Wayne State University & Detroit Medical Center, Detroit, MI, [USA. Email: hf9269@wayne.edu](USA. Email: hf9269@wayne.edu)  \ndoi: [https://doi.org/10.14740/jmc4093](https://doi.org/10.14740/jmc4093)  \nhead and neck, with an incidence of around 13,000 yearly in the United States and representing one-third of head and neck cancers [1] . The cancerous lesions are classified by location, either supraglottic, glottic, or subglottic, as well as by invasive characteristics and nodal metastases of the primary tumor. Treatment modalities differ by the tumor’s location and TNM staging; however, as treatments have advanced, the goal has been to emphasize laryngeal preserving modalities and move away from total laryngectomy. Radiation therapy is a standard option for all stages and one of the mainstay modalities of therapy for advanced cancers at the T3 and T4 stages [2] . Despite preserving the laryngeal architecture, radiation therapy to the neck is not without its particular side effects, with mucosal injury causing dysphagia and voice dysfunction in the short term [3] .  \nFurthermore, in addition to causing strictures, it has been suggested that long-term effects may stem from collateral radiation to the nearby carotid arteries. Radiation induces endothelial damage, proliferation, and fibrosis, which are thought tobe mechanisms for accelerating atherosclerosis of the carotid arteries, leading to an increased risk of stroke and transient ischemic attacks [4] . We present an interesting case of acute left eye blindness in a veteran patient with a history of laryngeal cancer status post chemoradiation and in the setting of a left ventricular (LV) thrombus on anticoagulation resulting ina diagnostic challenge in determining the etiology.  \nCase Report  \nInvestigations  \nOur","cbCaibugJpaFzQIq","https://ap.wps.com/l/cbCaibugJpaFzQIq","pdf",1255765,"English","# Abstract\n# Introduction\n# Case Report\n## Investigations\n## Diagnosis","[{\"question\":\"What does the case report focus on regarding acute left-sided visual loss?\",\"answer\":\"It focuses on identifying the cause of sudden acute left eye blindness in a patient with prior laryngeal cancer treated with chemoradiation and concurrent anticoagulation-related diagnostic complexity.\"},{\"question\":\"Which patient history and clinical context contribute to the diagnostic challenge?\",\"answer\":\"The patient’s history includes laryngeal cancer status post chemoradiation and anticoagulation for a left ventricular thrombus, both of which can influence vascular and thrombotic etiologies.\"},{\"question\":\"How were the potential causes evaluated in the investigations and diagnosis?\",\"answer\":\"Investigations included neuroimaging with CT, CTA, and MRI, and the diagnosis relied on imaging findings such as vascular occlusions and chronic infarcts.\"}]","Identifying the Cause of Acute Left-Sided Visual Loss - A Clinical Dilemma | PDF",1790244818]