[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-357876-105":3,"detail-sidebar-cat-0-en-105":85,"doc-detail-357876-en":134},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":78,"head_meta":80,"extra_data":82,"updated_unix":84},105,"en","hybrid-treatment-planning-in-breast-and-esophageal-cancer-a-feasible-approach-for-high-volume-radiotherapy-centers","Hybrid Treatment Planning in Breast and Esophageal Cancer - A Feasible Approach for High-Volume Radiotherapy Centers","","Objective evaluates the feasibility of hybrid intensity-modulated radiotherapy (IMRT) for patients with esophageal and breast cancer in a high-patient-volume setting. A retrospective study of 36 left breast and esophageal carcinoma patients compared 3D-CRT, IMRT, and hybrid techniques. Dosimetric outcomes assessed PTV coverage, conformity, and organ-at-risk doses, including lung, heart, spinal cord, and contralateral breast. Results show selective differences in coverage and critical-structure doses and support hybrid planning as a valuable option.",{"@graph":14,"@context":77},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/hybrid-treatment-planning-in-breast-and-esophageal-cancer-a-feasible-approach-for-high-volume-radiotherapy-centers/357876/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/hybrid-treatment-planning-in-breast-and-esophageal-cancer-a-feasible-approach-for-high-volume-radiotherapy-centers/357876.png","ImageObject",300,407,{"name":42,"@type":43},"nayy☆","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-28","2026-09-23",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",9,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69,73],{"name":60,"@type":61,"acceptedAnswer":62},"What is the study’s main objective?","Question",{"text":63,"@type":64},"To evaluate whether hybrid intensity-modulated radiotherapy is feasible for breast and esophageal cancer patients in a high-volume radiotherapy setup.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How many patients and which techniques were compared?",{"text":68,"@type":64},"Thirty-six retrospective patients were studied and compared across 3D-CRT, IMRT, and hybrid techniques.",{"name":70,"@type":61,"acceptedAnswer":71},"What dosimetric outcomes were analyzed?",{"text":72,"@type":64},"The study compared PTV coverage and conformity and assessed doses to organs at risk such as left lung, heart, spinal cord, and contralateral breast.",{"name":74,"@type":61,"acceptedAnswer":75},"Why might hybrid planning be valuable in high-volume centers?",{"text":76,"@type":64},"It has comparable planning time to IMRT and provides added benefit through reduced organ-at-risk doses, making it useful when patient load is high.","https://schema.org",{"og:url":32,"og:type":79,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":81,"canonical":32},"index,follow",{"doc_id":83,"site_id":7},357876,1790259392,{"code":4,"msg":86,"data":87},"success",[88,92,96,100,105,110,114,119,123,126,130],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":97,"show_sort_weight":98,"slug":99},"Exam",70,"exam",{"id":101,"doc_module":4,"doc_module_name":25,"category_name":102,"show_sort_weight":103,"slug":104},5,"Comic",60,"comic",{"id":106,"doc_module":4,"doc_module_name":25,"category_name":107,"show_sort_weight":108,"slug":109},6,"Technology",50,"technology",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":112,"slug":113},7,40,"healthcare",{"id":115,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},8,"Research & Report",30,"research-report",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":121,"slug":122},"Religion & Spirituality",20,"religion-spirituality",{"id":121,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":121,"slug":125},"World Cup","world-cup",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":127,"slug":129},10,"Lifestyle","lifestyle",{"id":131,"doc_module":4,"doc_module_name":25,"category_name":132,"show_sort_weight":101,"slug":133},19,"General","general",{"code":4,"msg":86,"data":135},{"doc_id":83,"user_id":136,"nickname":42,"user_avatar":137,"doc_module":4,"category_id":111,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":138,"file_id":139,"file_url":140,"file_type":141,"file_size":142,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":111,"language":143,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":144,"faqs":145,"seo_title":146,"seo_description":12,"update_tm":147,"read_time":148},962090893153,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc","RESEARCH ARTICLE  \n\n| Editorial Proc | ess: Submission:06/03/2025 Acceptance:01/27/2026 Published:02/05/2026 |\n| --- | --- |\n\nHybrid Treatment Planning in Breast and Esophageal Cancer:  \nA Feasible Approach for High-Volume Radiotherapy Centers Shraddha Srivastava1 *, Shyam Prasad S2, Atul Mishra3, Nara Moirangthem Singh4  \nAbstract  \nObjective: To evaluate the feasibility of hybrid intensity-modulated radiotherapy (IMRT) technique in patients with esophageal and breast cancer within a high-patient volume setup. Materials and methods: A total of 36 patients with carcinoma of the left breast and esophagus were retrospectively studied with 3D-CRT, IMRT and Hybrid techniques. 3D-CRT plans for esophageal cancer consisted of one anterior-postertior (AP) and two oblique beams, while IMRT consisted of seven beams. The hybrid plan consisted of AP and PA static beams combined with five conformal beams, with a weighting ratio of 5:5 and 4:6. In breast cases, hybrid planning involved two tangential static beams and three conformal beams with a weighting ratio of 7:3. Dosimetric parameters of the hybrid-IMRT plans were then compared with those of the 3D-CRT and IMRT plans. Results: In esophageal cancer patients, there was a significant difference found in the PTV coverage and conformity. The V20 and Dmean of left lung showed significant differences between IMRT and Hybrid IMRT. V25 and Dmean for heart showed reduced values in IMRT plan. The maximum dose to the spinal cord was higher in Hybrid IMRT compared to IMRT and 3D-CRT. In breast cancer patients, V20 and Dmean for the left lung were 23.77±4.28% and 11.09±1.70 Gy in hybrid plans; 26.50±5.06 % and 12.44±1.62 Gy in IMRT; and 25.47±5.07% and 11.52±1.54 Gy in 3D-CRT. The dose to the contralateral breast was higher in the IMRT plans. Conclusion: Considering its comparable planning time to IMRT and the added benefit of reduced OAR doses, hybrid planning could be a valuable option in high-patient-volume settings.  \nKeywords: Breast cancer-Conformal Radiotherapy-Esophageal cancer-Hybrid planning  \nAsian Pac J Cancer Prev, 27 (2), 527-533  \nIntroduction  \nBreast and esophageal cancers represent significant clinical challenges due to their high incidence and the complexity of their treatment. Breast cancer in women ranks as the top most common cancer while esophageal cancer is the tenth most common malignancy across the globe [1] . Radiotherapy plays a pivotal role in the management of both types of cancer, with advancementsin technology continually enhancing treatment efficacy and reducing side effects. Among these advancements, Intensity-Modulated Radiotherapy (IMRT) and threedimensional conformal radiotherapy (3D-CRT) have been extensively studied and implemented. 3D-CRT shapes the radiation beams to match the tumor’s threedimensional structure, offering improved targeting over traditional techniques. However, with 3D-CRT, the dose to the critical structures surrounding the target is higher compared to IMRT [2, 3] . IMRT, with its ability to  \nmodulate the intensity of the radiation beam, allows for precise targeting of the tumor while sparing surrounding healthy tissue. IMRT has advantages in terms of improved target coverage, better dose homogeneity and reduced normal tissue toxicity [4, 5] . However, in IMRT, thereis a possibility of dose spillage in the vicinity of critical structures and chances of setup errors with changes in the shape of tumor volume [6-8] .  \nRecently, hybrid techniques, which combine the strengths of both IMRT and 3D-CRT have emerged asa promising approach. Hybrid technique derives the benefits from both techniques. It aims to optimize tumor coverage and minimize exposure to surrounding organs at risk (OARs) by integrating the capabilities ofIMRT with that of conformal radiotherapy. Hybrid technique helps to minimize low-dose region around the target volume while increasing conformity and homogeneity [9] . In breast cancer, this is particularly crucial due to the pr","cbCaieTjBwWnLfDD","https://ap.wps.com/l/cbCaieTjBwWnLfDD","pdf",1689274,"English","# Abstract\n## Objective\n## Materials and Methods\n## Results\n## Conclusion\n# Introduction\n# Materials and Methods","[{\"question\":\"What is the study’s main objective?\",\"answer\":\"To evaluate whether hybrid intensity-modulated radiotherapy is feasible for breast and esophageal cancer patients in a high-volume radiotherapy setup.\"},{\"question\":\"How many patients and which techniques were compared?\",\"answer\":\"Thirty-six retrospective patients were studied and compared across 3D-CRT, IMRT, and hybrid techniques.\"},{\"question\":\"What dosimetric outcomes were analyzed?\",\"answer\":\"The study compared PTV coverage and conformity and assessed doses to organs at risk such as left lung, heart, spinal cord, and contralateral breast.\"},{\"question\":\"Why might hybrid planning be valuable in high-volume centers?\",\"answer\":\"It has comparable planning time to IMRT and provides added benefit through reduced organ-at-risk doses, making it useful when patient load is high.\"}]","Hybrid Treatment Planning in Breast and Esophageal Cancer - A Feasible Approach for High-Volume Radiotherapy Centers | PDF",1790132154,18]