[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-114287-en":3,"doc-seo-114287-105":29,"detail-sidebar-cat-0-en-105":90},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":4,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":13,"seo_description":14,"update_tm":27,"read_time":28},114287,137441390410,"Hazel","https://ap-avatar.wpscdn.com/avatar/2000252f4ab5702993?_k=1776741390130283984",7,"Healthcare","How the Endocrine System Works - Second Edition - Lecture Series Overview","How the Endocrine System Works, Second Edition, presents a lecture-based foundation for understanding hormone function from production to regulation and clinical application. It explains hormone composition and mechanisms, endocrine-hormone and immune-system interactions, and how hormone measurements guide diagnosis. The book reviews major endocrine disorders by organ system, including pituitary and hypothalamic conditions, thyroid hypo-/hyperfunction, adrenal gland pathology, glucose and calcium metabolism, reproductive endocrinology, and lipid disorders, plus multi-gland syndromes and paraneoplastic presentations.","Table of Contents  \nLecture 1: Clinical Trials, Evidence-Based Medicine, and Reading the  \nLiterature  \nTitle Page  \nCopyright  \nAcknowledgments  \nHow to Use this Book  \nLecture 1: An Overview  \nFUNCTION OF HORMONES  \nCOMPOSITION OF HORMONES  \nHOW HORMONES WORK  \nHORMONAL REGULATION  \nINTERACTIONS BETWEEN THE ENDOCRINE AND IMMUNE  \nSYSTEMS  \nHORMONE MEASUREMENTS  \nNOMENCLATURE OF ENDOCRINE DISORDERS  \nHYPOFUNCTION  \nTREATMENT OF HORMONE DEFICIENCY  \nENDOCRINE EXCESS SYNDROMES  \nIMAGING TESTS IN ENDOCRINOLOGY  \nGENETIC TESTING IN ENDOCRINOLOGY  \nEPILOGUE  \nLecture 2: Pituitary and Hypothalamus  \nPITUITARY AND HYPOTHALAMUS  \nGROWTH HORMONE  \nPROLACTIN  \nPITUTARY TUMORS  \nHYPOPITUITARISM  \nPOSTERIOR PITUITARY  \nLecture 3: The Thyroid  \nTHE THYROID  \nTHYROID HORMONES  \nEFFECTS OF THYROID HORMONE  \nTHYROID REGULATION  \nHYPOTHYROIDISM  \nHYPERTHYROIDISM AND THYROTOXICOSIS  \nTHYROID NODULES  \nDIFFERENTIATED (EPITHELIAL) THYROID CARCINOMA  \nMEDULLARY AND ANAPLASTIC THYROID CARCINOMA Lecture 4: Adrenal Gland  \nTHE ADRENAL GLANDS  \nADRENAL MEDULLA  \nINCIDENTAL ADRENAL TUMORS  \nLecture 5: Glucose Metabolism  \nGLUCOSE METABOLISM  \nOBESITY  \nHYPOGLYCEMIA  \nLecture 6: Calcium Metabolism  \nTRANSPORT AND REGULATION OF CALCIUM  \nHYPERCALCEMIA  \nHYPOCALCEMIA  \nBONE  \nVITAMIN D DEFICIENCY  \nLecture 7: Reproductive Endocrinology  \nAN INTRODUCTION TO REPRODUCTIVE  \nENDOCRINOLOGY  \nREGULATION OF TESTICULAR FUNCTION  \nOVARIAN CYCLE REGULATION  \nGONADAL DIFFERENTIATION  \nEFFECTS OF SEX STEROIDS  \nLecture 8: Lipid Disorders  \nLIPIDS  \nLIPOPROTEINS  \nHOW THE BODY OBTAINS LIPIDS  \nPRIMARY VERSUS SECONDARY DYSLIPIDEMIAS  \nPHYSICAL FINDINGS IN HYPERLIPIDEMIA  \nCONSEQUENCES OF HYPERLIPIDEMIA  \nTHERAPY OF HYPERLIPIDEMIA  \nLecture 9: Disorders of Multiple Endocrine Glands and Paraneoplastic Syndromes  \nPOLYENDOCRINE SYNDROMES  \nPARANEOPLASTIC SYNDROMES  \nAppendix: Clinical Trials, Evidence-Based Medicine, and Reading the Literature  \nSENSITIVITY, SPECIFICITY, AND PRETEST PROBABILITY  \nPRACTICAL EXAMPLES: NUMBER NEEDED TO TREAT  \n(NNT)  \nGlossary  \nIndex  \nEnd User License Agreement  \n[OceanofPDF.com](OceanofPDF.com)  \nThis new edition is also available as an e-book. For more details, please see  \n[www.wiley.com/buy/9781118931486](www.wiley.com/buy/9781118931486)  \n[or scan this QR code:](or scan this QR code:)  \n[OceanofPDF.com](OceanofPDF.com)  \nHow The Endocrine System Works  \nSECOND EDITION  \nJ. Matthew Neal, MD, MBA, CPE, FACP, FACE, FACPE Executive Medical Director, Academic Affairs  \nIndiana University Health Ball Memorial Hospital Muncie, Indiana  \nProfessor of Clinical Medicine Indiana University School of Medicine Indianapolis, Indiana  \nSeries Editor  \nLauren Sompayrac, PhD  \n[OceanofPDF.com](OceanofPDF.com)  \nThis edition first published 2016 © 2016 years by John Wiley & Sons Ltd.  \nFirst edition © 2001 by Blackwell Science Ltd.  \nRegistered office: John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK  \nEditorial offices: 9600 Garsington Road, Oxford, OX4 2DQ, UK The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK  \n111 River Street, Hoboken, NJ 07030-5774, USA  \nFor details of our global editorial offices, for customer services and for information about how to apply for permission to reuse the copyright material in this book please see our website at  \n[www.wiley.com/wiley-blackwell](www.wiley.com/wiley-blackwell)  \nThe right of Matthew Neal to be identified as the author of this work has been asserted in accordance with the UK Copyright, Designs and Patents Act 1988.  \nAll rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by the UK Copyright, Designs and Patents Act 1988, without the prior permission of the publisher.  \nDesignations used by companies to distinguish their products are often claimed as trademarks. All brand names and","cbCairFQ2deY30SI","https://ap.wps.com/l/cbCairFQ2deY30SI","pdf",9964286,1,343,"English","en",105,"# Lecture 1: An Overview\n## Function of hormones\n## Composition of hormones\n## How hormones work\n## Hormonal regulation\n## Endocrine and immune system interactions\n## Hormone measurements\n## Nomenclature of endocrine disorders\n## Hypofunction and treatment\n## Endocrine excess syndromes\n## Imaging and genetic testing in endocrinology\n## Epilogue\n# Lecture 2: Pituitary and Hypothalamus\n## Growth hormone and prolactin\n## Pituitary tumors and hypopituitarism\n## Posterior pituitary\n# Lecture 3: The Thyroid\n## Thyroid hormones and effects\n## Thyroid regulation\n## Hypothyroidism and hyperthyroidism\n## Thyroid nodules and carcinomas\n# Lecture 4: Adrenal Gland\n## Adrenal glands and adrenal medulla\n## Incidental adrenal tumors\n# Lecture 5: Glucose Metabolism\n## Obesity and hypoglycemia\n# Lecture 6: Calcium Metabolism\n## Transport and regulation of calcium\n## Hypercalcemia and hypocalcemia\n## Bone and vitamin D deficiency\n# Lecture 7: Reproductive Endocrinology\n## Regulation of testicular and ovarian function\n## Gonadal differentiation and sex steroids\n# Lecture 8: Lipid Disorders\n## Lipids and lipoproteins\n## Primary vs secondary dyslipidemias\n## Consequences and therapy\n# Lecture 9: Disorders of Multiple Endocrine Glands and Paraneoplastic Syndromes\n## Polyendocrine syndromes\n## Paraneoplastic syndromes\n# Appendix and Reference Materials\n## Clinical trials, evidence-based medicine, and reading the literature\n## Sensitivity, specificity, pretest probability\n## Number needed to treat (NNT)\n## Glossary and index","[{\"question\":\"What are the core steps in how hormones work according to the book?\",\"answer\":\"The book covers hormone function, composition, mechanisms of action, and hormonal regulation. It also describes how hormone measurements support clinical decision-making.\"},{\"question\":\"How does the book connect the endocrine system with other body systems?\",\"answer\":\"It explains interactions between the endocrine and immune systems. It also addresses paraneoplastic syndromes that link endocrine dysfunction with underlying diseases.\"},{\"question\":\"Which endocrine disorders and organ systems are covered across the lectures?\",\"answer\":\"The lectures address pituitary and hypothalamic disorders, thyroid hypo-/hyperfunction and cancers, adrenal gland conditions, glucose metabolism problems, calcium metabolism disorders, reproductive endocrinology, lipid disorders, and multi-gland/paraneoplastic syndromes.\"}]",1785398904,864,{"code":4,"msg":30,"data":31},"ok",{"site_id":24,"language":23,"slug":32,"title":13,"keywords":33,"description":14,"schema_data":34,"social_meta":85,"head_meta":87,"extra_data":89,"updated_unix":27},"how-the-endocrine-system-works-second-edition-lecture-series-overview","",{"@graph":35,"@context":84},[36,53,67],{"@type":37,"itemListElement":38},"BreadcrumbList",[39,43,47,50],{"item":40,"name":41,"@type":42,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":44,"name":45,"@type":42,"position":46},"https://docshare.wps.com/document/","Document",2,{"item":48,"name":12,"@type":42,"position":49},"https://docshare.wps.com/document/healthcare/",3,{"item":51,"name":13,"@type":42,"position":52},"https://docshare.wps.com/document/how-the-endocrine-system-works-second-edition-lecture-series-overview/114287/",4,{"url":51,"name":13,"@type":54,"author":55,"headline":13,"publisher":57,"fileFormat":60,"inLanguage":23,"description":14,"dateModified":61,"datePublished":61,"encodingFormat":60,"isAccessibleForFree":62,"interactionStatistic":63},"DigitalDocument",{"name":9,"@type":56},"Person",{"url":40,"name":58,"@type":59},"DocShare","Organization","application/pdf","2026-07-30",true,{"@type":64,"interactionType":65,"userInteractionCount":4},"InteractionCounter",{"@type":66},"ViewAction",{"@type":68,"mainEntity":69},"FAQPage",[70,76,80],{"name":71,"@type":72,"acceptedAnswer":73},"What are the core steps in how hormones work according to the book?","Question",{"text":74,"@type":75},"The book covers hormone function, composition, mechanisms of action, and hormonal regulation. It also describes how hormone measurements support clinical decision-making.","Answer",{"name":77,"@type":72,"acceptedAnswer":78},"How does the book connect the endocrine system with other body systems?",{"text":79,"@type":75},"It explains interactions between the endocrine and immune systems. It also addresses paraneoplastic syndromes that link endocrine dysfunction with underlying diseases.",{"name":81,"@type":72,"acceptedAnswer":82},"Which endocrine disorders and organ systems are covered across the lectures?",{"text":83,"@type":75},"The lectures address pituitary and hypothalamic disorders, thyroid hypo-/hyperfunction and cancers, adrenal gland conditions, glucose metabolism problems, calcium metabolism disorders, reproductive endocrinology, lipid disorders, and multi-gland/paraneoplastic syndromes.","https://schema.org",{"og:url":51,"og:type":86,"og:title":13,"og:site_name":58,"og:description":14},"article",{"robots":88,"canonical":51},"index,follow",{"doc_id":7,"site_id":24},{"code":4,"msg":5,"data":91},[92,96,100,104,109,114,117,122,127,130,134],{"id":20,"doc_module":4,"doc_module_name":45,"category_name":93,"show_sort_weight":94,"slug":95},"Story & Novel",90,"story-novel",{"id":46,"doc_module":4,"doc_module_name":45,"category_name":97,"show_sort_weight":98,"slug":99},"Literature",80,"literature",{"id":52,"doc_module":4,"doc_module_name":45,"category_name":101,"show_sort_weight":102,"slug":103},"Exam",70,"exam",{"id":105,"doc_module":4,"doc_module_name":45,"category_name":106,"show_sort_weight":107,"slug":108},5,"Comic",60,"comic",{"id":110,"doc_module":4,"doc_module_name":45,"category_name":111,"show_sort_weight":112,"slug":113},6,"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":45,"category_name":12,"show_sort_weight":115,"slug":116},40,"healthcare",{"id":118,"doc_module":4,"doc_module_name":45,"category_name":119,"show_sort_weight":120,"slug":121},8,"Research & Report",30,"research-report",{"id":123,"doc_module":4,"doc_module_name":45,"category_name":124,"show_sort_weight":125,"slug":126},9,"Religion & Spirituality",20,"religion-spirituality",{"id":125,"doc_module":4,"doc_module_name":45,"category_name":128,"show_sort_weight":125,"slug":129},"World Cup","world-cup",{"id":131,"doc_module":4,"doc_module_name":45,"category_name":132,"show_sort_weight":131,"slug":133},10,"Lifestyle","lifestyle",{"id":135,"doc_module":4,"doc_module_name":45,"category_name":136,"show_sort_weight":105,"slug":137},19,"General","general"]