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Surgical technique advances, improved biomaterials, and evolving implant technology have accelerated progress toward better aesthetic outcomes and lower patient morbidity. Prepectoral reconstruction gained momentum by eliminating animation deformity risk and reducing postoperative pain. Ongoing issues include mastectomy flap thickness and long-term oncologic and aesthetic results. Additional developments—nipple-sparing mastectomy, NAC neurotization, biologic matrices and synthetic meshes, and next-generation implants—must be balanced against concerns such as breast implant-related cancers and breast implant illness (BII).",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/hot-topics-in-implant-based-breast-reconstruction-review/461353/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/hot-topics-in-implant-based-breast-reconstruction-review/461353.png","ImageObject",300,407,{"name":92,"@type":93},"Aldword","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What are the main goals of implant-based breast reconstruction innovations discussed in the review?","Question",{"text":112,"@type":113},"The review emphasizes improving aesthetic outcomes while minimizing patient morbidity. It also highlights the need to balance innovation with oncologic and systemic safety concerns.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Why has prepectoral reconstruction become popular in implant-based breast reconstruction?",{"text":117,"@type":113},"Prepectoral reconstruction avoids elevating the pectoralis major muscle, which reduces postoperative pain and eliminates muscle spasm. It is also associated with earlier return to baseline arm function and quicker return to daily life.",{"name":119,"@type":110,"acceptedAnswer":120},"Which major safety concerns must be weighed alongside new reconstructive techniques?",{"text":121,"@type":113},"The review discusses breast implant-related cancers, including breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), and the ongoing debate regarding breast implant illness (BII). It also notes cancer recurrence concerns after nipple-sparing mastectomy.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},461353,1790790355,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":36,"preview_page_count":4},2336478940917,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","Review  \nHot Topics in Implant-Based Breast Reconstruction Thomas J. Sorenson , Carter J. Boyd and Nolan S. Karp *  \nAcademic Editor: Dennis Paul Orgill  \nReceived: 8 December 2025  \nRevised: 25 December 2025  \nAccepted: 27 December 2025  \nPublished: 29 December 2025  \nCopyright: © 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.  \nHansjorg Wyss Department of Plastic Surgery, NYU-Langone Health, New York, NY 10016, USA  \n* [Correspondence: nolan.karp@nyulangone.org](Correspondence: nolan.karp@nyulangone.org)  \nAbstract  \nImplant-based breast reconstruction (IBBR) remains the most common form of postmastectomy reconstruction worldwide, offering patients a reliable and accessible option to restore breast contour. Advances in surgical technique, biomaterials, and implant technology have driven rapid evolution in the field, with the dual goals of improving aesthetic outcomes and minimizing patient morbidity. The prepectoral plane has been popularized due to the eliminated risk of animation deformity and reduced postoperative pain. Some concerns remain regarding mastectomy flap thickness and long-term oncologic and aesthetic outcomes. Concurrently, nipple-sparing mastectomy has improved aesthetic results and enabled surgeons to move beyond just restoring breast form and improve functional recovery as well, as demonstrated by surgical efforts aimed at restoring nipple–areolar complex (NAC) sensation. Adjunctive use of biologic matrices and synthetic meshes has broadened reconstructive options, while next-generation implants seek to further enhance outcomes. Balanced against these innovations are important oncologic and systemic safety concerns, including breast implant-related cancers and the ongoing debate over breast implant illness (BII) . This review highlights eight current “hot topics”in implant-based breast reconstruction: (1) prepectoral reconstruction,(2) nipple-sparing mastectomy,(3) oncoplastic techniques,(4) nipple–areolar complex (NAC) neurotization,(5) biologic matrices and synthetic meshes,(6) next-generation implants,(7) optimizing aesthetic outcomes, and (8) implant-associated cancer and systemic concerns. Together, these areas define the current landscape of innovation, controversy, and future directions in implant-based reconstruction.  \nKeywords: breast implant; breast reconstruction; nipple-sparing mastectomy; prepectoral; neurotization; breast implant-associated anaplastic large cell lymphoma; BII; acellular dermal matrix; mesh  \n1. Introduction  \nImplant-based breast reconstruction (IBBR) remains the most performed method of post-mastectomy reconstruction worldwide. Over the past decades, advances in surgical technique, biomaterials, and implant technology have driven a paradigm shift in how these procedures are performed. Surgeons have moved away from traditional subpectoral placement toward prepectoral reconstruction, enabled by improved mastectomy flap viability and the widespread use of acellular dermal matrices (ADMs) and synthetic meshes. Atthe same time, increasing adoption of nipple-sparing mastectomy (NSM) has transformed both the aesthetic goals and the technical challenges of reconstruction. While restoring breast form has always been central, contemporary practice also prioritizes function, sensation, and patient-reported satisfaction. Emerging efforts at nipple–areolar complex (NAC)  \nneurotization reflect this trend, as do adjunctive strategies such as autologous fat grafting and 3D-based aesthetic analysis. Parallel to these surgeon-driven innovations, industry advances in implant design also seek to improve both safety and outcomes.  \nNevertheless, controversy persists. Cancer recurrences after NSM, breast implantassociated anaplastic large cell lymphoma (BIA-ALCL), and the broader phenomenon of “breast implant illness”(BII) have raised new questions rega","cbCail4SrZa8hTdP","https://ap.wps.com/l/cbCail4SrZa8hTdP","pdf",1201953,16,"English","# Abstract\n# Introduction\n# Prepectoral Breast Reconstruction","[{\"question\":\"What are the main goals of implant-based breast reconstruction innovations discussed in the review?\",\"answer\":\"The review emphasizes improving aesthetic outcomes while minimizing patient morbidity. It also highlights the need to balance innovation with oncologic and systemic safety concerns.\"},{\"question\":\"Why has prepectoral reconstruction become popular in implant-based breast reconstruction?\",\"answer\":\"Prepectoral reconstruction avoids elevating the pectoralis major muscle, which reduces postoperative pain and eliminates muscle spasm. It is also associated with earlier return to baseline arm function and quicker return to daily life.\"},{\"question\":\"Which major safety concerns must be weighed alongside new reconstructive techniques?\",\"answer\":\"The review discusses breast implant-related cancers, including breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), and the ongoing debate regarding breast implant illness (BII). It also notes cancer recurrence concerns after nipple-sparing mastectomy.\"}]","Hot Topics in Implant-Based Breast Reconstruction - Review | PDF",1790761413]