[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-403329-105":3,"doc-detail-403329-en":81,"detail-sidebar-cat-0-en-105":99},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","hiv-pre-exposure-prophylaxis-prep-borders-protocol-version-2","HIV Pre-Exposure Prophylaxis (PrEP) - Protocol Borders - Version 2","","Borders Protocol for HIV Pre-Exposure Prophylaxis (PrEP) (Version 2, SH018/2.1) provides section-by-section clinical guidance for assessing eligibility, counseling, baseline testing, dosing, restarting strategies, and follow-up planning. It specifies simplified HIV testing workflows based on recent test history and risk, clarifies when uPCR is indicated (baseline only or clinician request for renal abnormalities), and emphasizes strict adherence for weekly dosing. The protocol outlines PrEP supply timing, reduced monitoring for stable patients using renal eGFR schedules, and standardized coding of PrEP-related attendances. It also includes educational background on PrEP and key resources for further information.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/hiv-pre-exposure-prophylaxis-prep-borders-protocol-version-2/403329/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/hiv-pre-exposure-prophylaxis-prep-borders-protocol-version-2/403329.png","ImageObject",300,407,{"name":42,"@type":43},"Riley West","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-29","2026-09-27",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",8,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What does the protocol say about baseline HIV testing when starting PrEP?","Question",{"text":63,"@type":64},"Perform an HIV test on the day PrEP is provided. Guidance varies by whether the patient had a negative HIV test within 3 months and whether high-risk sex occurred since then, with repeat testing scheduled at 3 months, 4 weeks, or based on baseline PoCT/serology when no recent negative is recorded.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"When is uPCR required for people starting or on PrEP?",{"text":68,"@type":64},"uPCR is routinely indicated only at baseline. Routine uPCR is required only at clinician request for patients with renal abnormalities, and most PrEP users do not require routine uPCR or urinalysis.",{"name":70,"@type":61,"acceptedAnswer":71},"How should PrEP dosing be managed if doses are missed or restarting on-demand?",{"text":72,"@type":64},"The protocol emphasizes that four doses per week allows no leeway for missed doses. If restarting on-demand less than 4 days after the last dose, restart with a single dose; if 4 or more days have passed, restart with a double dose.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},403329,1790857037,{"code":4,"msg":82,"data":83},"success",{"doc_id":79,"user_id":84,"nickname":42,"user_avatar":85,"doc_module":4,"category_id":86,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":87,"file_id":88,"file_url":89,"file_type":90,"file_size":91,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":92,"language":93,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":94,"faqs":95,"seo_title":96,"seo_description":12,"update_tm":97,"read_time":98,"preview_page_count":4},1099523885074,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc",7,"| Title | HIV Pre-Exposure Prophylaxis (PrEP) |\n| --- | --- |\n| Document Type | Clinical Protocol |\n| Version number | SH018/2.1 |\n| Approval/Issue date | April 2021 |\n| Review dated | April 2023 |\n| Approved by | Dr Sally Wielding |\n| Owner/Person Responsible | Dr Sally Wielding |\n| Developed by | Dr Dan Clutterbuck |\n| Reviewed by | Dr Sally Wielding |\n| Healthcare Inequality Impact Assessed\u003Cbr>(statutory for policies) | N/R |\n\nBorders Protocol for HIV Pre-Exposure Prophylaxis (PrEP)  \nWhat’s New in Version 2:  \nImportant changes section by section:  \n1.1 More information  \nNew ibase guides are available and the BASHH/BHIVA UK Guideline on PrEP has been published  \n2.2 Buying PrEP online is still an option and the cost is now as low as £18 for each month’s supply. If you get, or intend to get your PrEP online you can have your monitoring done at our clinics.  \n3 PrEP appointments  \nGive advice and information and perform baseline tests for any patient requesting PrEP.  \n5 5. 1: uPCR is only routinely indicated at baseline. Routine uPCR is only required at clinician request in patients with renal abnormalities. Most PrEP users will not require routine uPCR or urinalysis  \n5.2 HIV Testing at baseline  \nIn all circumstances perform an HIV test on the day of providing PrEP. HIV testing guidance has been simplified  \nIf negative HIV test in the last 3 months with no high risk sex since, start PrEP, test today and repeat HIV test in 3 months.  \nIf negative HIV test in the last 3 months but with high risk sex since then, start PrEP, test today and repeat HIV test in 4 weeks.  \nIf no recorded negative HIV test in the last 3 months and risks since last tested, perform PoCT (Insti syphilis/HIV) and serology at baseline, start PrEP and test again at 1 or 3 months depending on recent risks  \n4 6.1 PrEP dosing: it should be emphasized that four does per week does not allow ANY leeway for missed doses  \n6.2 If restarting On-demand PrEP less than 4 days after the last dose was taken, restart with a single dose. If 4 or more days have passed since the last dose was taken, restart with a double dose.  \n7.1 Initial PrEP supply  \nDispense one month (30 tablets) of PrEP if eligible and given an appointment for follow up atthe GMC in 1 month. If confident about dosing and with no other medical issues, arrange HIV testing only and give 3 months supply.  \nIf no medical or other issues and absolutely confident about lack of HIV risk in the month prior to PrEP start, review can be arranged for 3 months.  \nWhat’s New in Version 2:  \n8.3 Reduced PrEP Monitoring for stable patients:  \nThe frequency of renal monitoring for stable patients has reduced  \nProtocol for provision of 6 month PrEP prescription and 12 monthly renal monitoring Routine monitoring:  \nPatients under the age of 40 years and with baseline eGFR >90ml/min and no other risk factors require eGFR at baseline and 12 monthly. uPCR is not required.  \nPatients over the age of 40 years and with baseline eGFR >90ml/min and no other risk factors require eGFR at baseline and 6 monthly. uPCR is not required.  \nEnter in the clinical note the date when the next eGFR is required and if uPCR is indicated (usually not)  \n6-monthly prescriptions  \nPatients who are stable on PrEP may be able to move to the provision of 6 monthly prescriptions after a minimum of 6 months of prescribing. They should continue to attend for an STI screen 3 monthly.  \nPatients requiring additional monitoring can move to 6 monthly prescriptions and 6 monthly eGFR if stable for 1 year or 3 eGFR results on PrEP, after discussion with senior clinician.  \n10 PrEP coding  \nAll attendances for PrEP should be coded (ie every time PrEP is prescribed, or every time that those who are self-sourcing PrEP attend for monitoring) .  \n1) What is PrEP?  \nPrEP stands for “pre-exposure prophylaxis”. PrEP is taken before sex; “pre-exposure”.“Prophylaxis”means to prevent infection; in this case HIV. So, PrEP is used by HIV negative people to prev","cbCaiqc0tEZnR6Ta","https://ap.wps.com/l/cbCaiqc0tEZnR6Ta","pdf",1260080,18,"English","# What’s New in Version 2\n## More information and guideline publications\n## Buying PrEP online and monitoring options\n## PrEP appointments and baseline tests\n## uPCR indications and HIV testing at baseline\n## PrEP dosing and restarting on-demand\n## Initial PrEP supply and follow-up planning\n## Reduced PrEP monitoring for stable patients\n## PrEP coding\n## What is PrEP?","[{\"question\":\"What does the protocol say about baseline HIV testing when starting PrEP?\",\"answer\":\"Perform an HIV test on the day PrEP is provided. Guidance varies by whether the patient had a negative HIV test within 3 months and whether high-risk sex occurred since then, with repeat testing scheduled at 3 months, 4 weeks, or based on baseline PoCT/serology when no recent negative is recorded.\"},{\"question\":\"When is uPCR required for people starting or on PrEP?\",\"answer\":\"uPCR is routinely indicated only at baseline. Routine uPCR is required only at clinician request for patients with renal abnormalities, and most PrEP users do not require routine uPCR or urinalysis.\"},{\"question\":\"How should PrEP dosing be managed if doses are missed or restarting on-demand?\",\"answer\":\"The protocol emphasizes that four doses per week allows no leeway for missed doses. If restarting on-demand less than 4 days after the last dose, restart with a single dose; if 4 or more days have passed, restart with a double dose.\"}]","HIV Pre-Exposure Prophylaxis (PrEP) - Protocol Borders - Version 2 | PDF",1790538906,45,{"code":4,"msg":82,"data":100},[101,105,109,113,118,123,126,130,135,138,142],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":102,"show_sort_weight":103,"slug":104},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":106,"show_sort_weight":107,"slug":108},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":110,"show_sort_weight":111,"slug":112},"Exam",70,"exam",{"id":114,"doc_module":4,"doc_module_name":25,"category_name":115,"show_sort_weight":116,"slug":117},5,"Comic",60,"comic",{"id":119,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":121,"slug":122},6,"Technology",50,"technology",{"id":86,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":124,"slug":125},40,"healthcare",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":127,"show_sort_weight":128,"slug":129},"Research & Report",30,"research-report",{"id":131,"doc_module":4,"doc_module_name":25,"category_name":132,"show_sort_weight":133,"slug":134},9,"Religion & Spirituality",20,"religion-spirituality",{"id":133,"doc_module":4,"doc_module_name":25,"category_name":136,"show_sort_weight":133,"slug":137},"World Cup","world-cup",{"id":139,"doc_module":4,"doc_module_name":25,"category_name":140,"show_sort_weight":139,"slug":141},10,"Lifestyle","lifestyle",{"id":143,"doc_module":4,"doc_module_name":25,"category_name":144,"show_sort_weight":114,"slug":145},19,"General","general"]