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This paper offers a perspective on advances in exercise oncology over the past four decades, from early foundational studies through major randomized controlled trials. It reviews adult and pediatric cancer research, including both clinical work and investigations of biological mechanisms linking exercise and cancer. The paper also examines strengths, weaknesses, opportunities, and threats for the International Society of Exercise Oncology (ISEO) as it seeks to support research, collaboration, education, awareness, and translation into practice.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/history-informing-the-future-of-exercise-oncology-monograph/372630/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/history-informing-the-future-of-exercise-oncology-monograph/372630.png","ImageObject",300,407,{"name":92,"@type":93},"Dipper","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-28","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main focus of this monograph?","Question",{"text":112,"@type":113},"It provides a viewpoint on the development of exercise oncology over the past four decades and how it can inform future directions, including the creation of the International Society of Exercise Oncology (ISEO).","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which types of cancer research does the paper review?",{"text":117,"@type":113},"It briefly reviews research spanning adult and pediatric cancers, from early foundation studies to larger randomized controlled trials, alongside work on biological mechanisms.",{"name":119,"@type":110,"acceptedAnswer":120},"Why is ISEO described as important for the field?",{"text":121,"@type":113},"The paper argues that ISEO can support research, enable collaborations, facilitate education and training, raise awareness, and help translate research into clinical practice.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},372630,1791168605,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},1374404997633,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Journal of the National Cancer Institute Monographs, 2025, 2025(71), 306–314  \n[https://doi.org/10.1093/jncimonographs/lgaf025](https://doi.org/10.1093/jncimonographs/lgaf025)  \nMonograph  \nHistory informing the future of exercise oncology  \nDaniel A. Galv~ao , PhD􀀃 ,1 ,2, Kerry S. Courneya , PhD3, Alejandro Lucia , MD, PhD4, 5, Anne M. May, PhD6, 7, Karen Mustian , PhD, MPH8, Allison B. Warner, MD, PhD9, Wiskemann Joachim, PhD10, Karen Wonders , PhD11, Kathryn H. Schmitz, PhD, MPH12, Robert U. Newton, PhD, DSc1, 2  \n1Exercise Medicine Research Institute, Edith Cowan University, Joondalup, Western Australia, Australia  \n2School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia 3Faculty of Kinesiology, Sport, and Recreation, College of Health Sciences, University of Alberta, Edmonton, Canada 4Research Institute of the Hospital 12 de Octubre (‘imas12’), Madrid, Spain  \n5Faculty of Medicine, Department of Sports Sciences, Health and Sports Universidad Europea de Madrid, Madrid, Spain  \n6Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands 7Department of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands 8Department of Surgery, Wilmot Cancer Institute, University of Rochester Medical Centre, Rochester, NY, United States  \n9Division of Oncology, Department of Medicine, Stanford Medicine, Stanford, CA, United States  \n10Working Group Exercise Oncology, Division of Medical Oncology, National Centre for Tumour Diseases Heidelberg and Heidelberg University Clinic, Heidelberg, Germany  \n11Exercise Science Program, Wright State University, Dayton, OH, United States  \n12Division of Hematology and Oncology, University of Pittsburgh, Pittsburgh, PA, United States  \n􀀃 Corresponding author: Daniel A. Galv~ao, PhD, FACSM, FESSA, Exercise Medicine Research Institute, Edith Cowan University; 270 Joondalup Drive, Joondalup, WA 6027, Australia ([d.galvao@ecu.edu.au](d.galvao@ecu.edu.au)) .  \nAuthor Contributions: K. H. Schmitz and R. U. Newton joint last authors.  \nAbstract  \nExercise is increasingly recognized by patients, clinicians, and allied health professionals globally as an important component of cancer care. In this paper, we provide a viewpoint on developments in exercise oncology over the past 4 decades leading up to the creation of the International Society of Exercise Oncology (ISEO) . We briefly review research in adult and pediatric cancers from early foundation studies to larger randomized controlled trials published in mainstream oncology journals alongside critical work undertaken in exercise and cancer biological mechanisms. We also discuss potential strengths, weaknesses, opportunities, and threats facing ISEO in becoming a global forum for exercise oncology. Building on the foundational work undertaken over the past 4 decades by researchers, clinicians, and practitioners, ISEO provides an opportunity to support research, leverage collaborations and partnerships, facilitate education and training, increase awareness of exercise oncology, and support translation of research to clinical practice, ultimately improving the quality and quantity of life for people with cancer.  \nIntroduction  \nIt is important to retrospectively examine past milestones in exercise and cancer to inform future directions and continuing progress in a field that is increasingly recognized by patients, clinicians, and allied health professionals globally as a critical component of cancer care. Here we provide a viewpoint on developments in this exciting field of exercise medicine for cancer, termed exercise oncology , which continues to mature and gain recognition with strong evidence of improved patient outcomes, and endorsement by oncology and exercise science organizations internationally. In undertaking this endeavor, we selected a few key seminal events acknowledging that there are m","cbCaidaE8WRPDaDv","https://ap.wps.com/l/cbCaidaE8WRPDaDv","pdf",2824685,"English","# Abstract\n# Introduction\n# Early discoveries and observations","[{\"question\":\"What is the main focus of this monograph?\",\"answer\":\"It provides a viewpoint on the development of exercise oncology over the past four decades and how it can inform future directions, including the creation of the International Society of Exercise Oncology (ISEO).\"},{\"question\":\"Which types of cancer research does the paper review?\",\"answer\":\"It briefly reviews research spanning adult and pediatric cancers, from early foundation studies to larger randomized controlled trials, alongside work on biological mechanisms.\"},{\"question\":\"Why is ISEO described as important for the field?\",\"answer\":\"The paper argues that ISEO can support research, enable collaborations, facilitate education and training, raise awareness, and help translate research into clinical practice.\"}]","History informing the future of exercise oncology - Monograph | PDF",1790194988,23]