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A facility-based cross-sectional design covered May 1 to June 30, 2020. Findings showed cervical cancer was the leading cause (71%), with squamous cell carcinoma dominating among cancers (96.4%). Precancerous lesions were mainly high-grade squamous intraepithelial lesions (68.4%), and endocervical polyps were the most frequent benign lesions (59.3%).",{"@graph":69,"@context":126},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/histopathologic-patterns-and-factors-associated-with-cervical-lesions-at-jimma-medical-center-jimma-southwest-ethiopia-a-two-year-cross-sectional-study/327451/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/histopathologic-patterns-and-factors-associated-with-cervical-lesions-at-jimma-medical-center-jimma-southwest-ethiopia-a-two-year-cross-sectional-study/327451.png","ImageObject",300,407,{"name":92,"@type":93},"Emma Wilson","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-04","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118,122],{"name":109,"@type":110,"acceptedAnswer":111},"What was the study objective regarding cervical lesions?","Question",{"text":112,"@type":113},"To determine histopathologic patterns and factors associated with cervical lesions at Jimma Medical Center from September 12, 2017 to September 12, 2019.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What study design and time frame were used?",{"text":117,"@type":113},"A 2-year facility-based cross-sectional study was conducted from May 1 to June 30, 2020.",{"name":119,"@type":110,"acceptedAnswer":120},"Which cervical condition was most common and what were the leading subtypes?",{"text":121,"@type":113},"Cervical cancer was the most common cause (71%). 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PLoS ONE 19(4): e0301559 .  \n[https://doi.org/10.1371/journal.pone.0301559](https://doi.org/10.1371/journal.pone.0301559)  \n[Editor:](Editor: Andrea Giannini)[ Andrea Giannini](Editor: Andrea Giannini), [Sapienza University of](Sapienza University of)[ ](Sapienza University of)[Rome: Universita degli Studi di Roma La Sapienza](Rome: Universita degli Studi di Roma La Sapienza), ITALY  \nReceived: June 10, 2023  \nAccepted: March 15, 2024  \nPublished: April 18, 2024  \nPeer Review History: PLOS recognizes the benefits of transparency in the peer review process; therefore, we enable the publication of all of the content of peer review and author responses alongside final, published articles. The editorial history of this article is available here:  \n[https://doi.org/10.1371/journal.pone.0301559](https://doi.org/10.1371/journal.pone.0301559)  \n[Copyright:](Copyright:) © [2024 Tirkaso et al](2024 Tirkaso et al). This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.  \nData Availability Statement: All relevant data are within the manuscript and its Supporting Information files.  \nRESEARCH ARTICLE  \nHistopathologic patterns and factors associated with cervical lesions at Jimma Medical Center, Jimma, Southwest Ethiopia: A two-year cross-sectional study  \nBirhanu HailuTirkaso1 *, Tesfaye Hurgesa Bayisa2, Tewodros Wubshet Desta3  \n1 Department of Biomedical Sciences, Mizan-Tepi University, Mizan, Southwestern Region, Ethiopia,  \n2 Department of Pathology, Jimma University, Jimma, Oromia, Ethiopia, 3 Department of Pathology, Dire Dawa University, Dire Dawa, Ethiopia  \n* [birhanuhailu@mtu.edu.et](birhanuhailu@mtu.edu.et)  \nAbstract  \nBackground  \nThe cervix is the lower portion of the uterus, which connects this organ to the vagina through the endocervical canal.  \nObjective  \nThis study aimed to determine the histopathologic patterns and factors associated with cervical lesions at Jimma Medical Center from September 12, 2017, to September 12, 2019.  \nMethods  \nA 2-year facility-based cross-sectional study was conducted from May 1 to June 30, 2020.  \nResult  \nIn this study, cervical cancer was the most common (71%) cause of cervical lesions. Squamous cell carcinoma was the most frequent cervical cancer diagnosed during the study, accounting for 96 .4% of 331 cancerous cases, followed by adenocarcinoma (3 .3%) . Highgrade squamous intraepithelial lesions were the most frequently diagnosed precancerous lesions, accounting for 68 .4% of cases. Endocervical polyps were the most commonly diagnosed benign lesions, accounting for 59 .3% of cases.  \nConclusion  \nThe maximum age distribution of cervical lesions was in the 41–50-year age range. Squamous cell carcinoma was the most frequent type of cervical cancer. High-grade squamousintraepithelial lesions were the most frequently diagnosed precancerous cervical lesions. The most common benign cervical lesions were endocervical polyps.  \nFunding: The author(s) received no specific funding for this work.  \nCompeting interests: The authors have declared that no competing interests exist.  \nRecommendation  \nWe recommend educating the community to improve health-seeking behavior and on possible preventive strategies for cervical cancer.  \n1. Introduction  \n1.1. Background  \nThe endocervical canal connects the uterus to the vagina through the cervix, which is the bottom part of the uterus. Non-keratinizing squamous epithelium covers the majority ofthe exocervix. A layer of columnar mucus-secreting cells makes up the glandular mucosa ofthe endocervix, and the intersection between the squamous and glandula","cbCaimZZLQVZd43K","https://ap.wps.com/l/cbCaimZZLQVZd43K","pdf",1345062,17,"English","# Abstract\n## Background\n## Objective\n## Methods\n## Result\n## Conclusion\n# 1. Introduction\n## 1.1. Background","[{\"question\":\"What was the study objective regarding cervical lesions?\",\"answer\":\"To determine histopathologic patterns and factors associated with cervical lesions at Jimma Medical Center from September 12, 2017 to September 12, 2019.\"},{\"question\":\"What study design and time frame were used?\",\"answer\":\"A 2-year facility-based cross-sectional study was conducted from May 1 to June 30, 2020.\"},{\"question\":\"Which cervical condition was most common and what were the leading subtypes?\",\"answer\":\"Cervical cancer was the most common cause (71%). Squamous cell carcinoma accounted for 96.4% of 331 cancerous cases, followed by adenocarcinoma (3.3%).\"},{\"question\":\"What were the main precancerous and benign histopathologic findings?\",\"answer\":\"High-grade squamous intraepithelial lesions were the most frequent precancerous lesions (68.4%). Endocervical polyps were the most common benign lesions (59.3%).\"}]","Histopathologic patterns and factors associated with cervical lesions at Jimma Medical Center, Jimma, Southwest Ethiopia - A two-year cross-sectional study | PDF",1789977231,43]