[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-457087-105":59,"doc-detail-457087-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","highly-efficient-free-breathing-whole-chest-equilibrium-phase-bt1ress-mr-angiography-initial-clinical-experience","Highly efficient, free-breathing whole-chest equilibrium phase bT1RESS MR angiography - Initial clinical experience","","Background: Both computed tomography angiography and contrast-enhanced MR angiography suffer marked image-quality deterioration after the first pass, restricting the useful post-contrast window to only tens of seconds. To address this, equilibrium phase balanced T1 relaxation-enhanced steady-state (bT1RESS) enables diagnostic CEMRA acquisition for tens of minutes. This study implements a highly efficient free-breathing whole-chest bT1RESS and evaluates it in a patient series. IRB-approved protocol and technical validation follow. ",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/highly-efficient-free-breathing-whole-chest-equilibrium-phase-bt1ress-mr-angiography-initial-clinical-experience/457087/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/highly-efficient-free-breathing-whole-chest-equilibrium-phase-bt1ress-mr-angiography-initial-clinical-experience/457087.png","ImageObject",300,407,{"name":92,"@type":93},"Kyle","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What problem does the equilibrium phase bT1RESS approach address in angiography?","Question",{"text":112,"@type":113},"Post-contrast angiographic image quality declines rapidly after the first pass, limiting the usable scan window to tens of seconds. bT1RESS is designed to enable diagnostic CEMRA beyond this limited window.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the free-breathing whole-chest bT1RESS sequence evaluated in the study?",{"text":117,"@type":113},"IRB-approved imaging was performed on 34 patients using a standard CMR protocol plus a post-contrast prototype navigator-gated whole-chest bT1RESS sequence with GRAPPA acceleration (2×2 or 3×2 slice x phase).",{"name":119,"@type":110,"acceptedAnswer":120},"What results were reported for scan time and image quality?",{"text":121,"@type":113},"Median scan time was shorter with 3×2 acceleration (1.25 min) than with 2×2 acceleration (2.21 min). Good-to-excellent visualization of major cardiovascular structures was reported in all cases with 3×2 acceleration and all but one with 2×2 acceleration, supporting overall diagnostic quality.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},457087,1791165059,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":52,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},3985741905716,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","Journal of Cardiovascular Magnetic Resonance 27 (2025) 101922  \nContents lists available at ScienceDirect  \nJournal of Cardiovascular Magnetic Resonance  \njournal [homepage:](homepage: www.sciencedirect.com/journal/joc mr)[ www.sciencedirect.com/journal/joc mr](homepage: www.sciencedirect.com/journal/joc mr)  \nOriginal research  \nHighly efficient, free-breathing whole-chest equilibrium phase bT1RESS MR angiography: Initial clinical experience  \nRobert R. Edelmana,b,⁎, Amit Pursnania,c, Kevin Leea,c, Hang Chend,e, Reza Nezafatd,e, Tess Wallacef, Nondas Leloudasa, Derek Clarkea, Ioannis Koktzogloua,c  \na NorthShore University HealthSystem, Evanston, IL, United States  \nb Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States c Pritzker School of Medicine, University of Chicago, Chicago, IL, United States  \nd Beth Israel Deaconess Medical Center, Boston, MA, United States  \ne Harvard Medical School, Boston, MA, United States f Siemens Healthineers, Boston, MA, United States  \nA R T I C L E I N F O  \nKeywords:  \nBalanced T1 relaxation-enhanced steady-state Navigator-gated  \nEquilibrium phase  \nWhole-chest  \nElectrocardiographic (ECG) gating Magnetic resonance  \nMR angiography  \nCardiac  \nGreat Vessels  \nGadolinium-based contrast agent  \nA B S T R A C T  \nBackground: A fundamental limitation of both computed tomography angiography (CTA) and contrast-enhanced MRA (CEMRA) is that angiographic image quality greatly deteriorates when scans are obtained after the first pass, so that the useful post-contrast scan window is limited to a few tens of seconds. To overcome this limitation, we recently described a breath-hold, slab-selective technique called equilibrium phase balanced T1 relaxation-enhanced steady-state (bT1RESS) that permits diagnostic CEMRA to be obtained for tens of minutes after contrast agent infusion. Further improving upon this technique, we implemented a highly efficient freebreathing version for very rapid whole-chest imaging and tested it in a series of patients.  \nMain body: This study was IRB approved. 34 patients with cardiovascular indications were imaged using a standard CMR protocol plus a post-contrast prototype navigator-gated, whole-chest bT1RESS sequence using either 2×2 or 3×2 (slice x phase) generalized autocalibrating partially parallel acquisition (GRAPPA) acceleration.  \nResults: Median scan time for 20 patients using 3×2 acceleration was 1.25 min vs. 2.21 min for 14 patients using 2×2 acceleration. Mean blood pool-to-muscle signal intensity ratio for bT1RESS obtained > 20 min post-contrast was 88% of the value for scans obtained \u003C 5 min post-contrast. Inline reconstruction time for a complete 128-slice data set was \u003C 15 s. Good-to-excellent image quality and visualization of the aorta, pulmonary arteries and veins, coronary origins, coronary sinus, left atrial appendage, atria and ventricles were obtained in all cases with 3×2 acceleration and all but one case with 2×2 acceleration. There was also excellent correlation (0.92/ 0.93, p \u003C 0.001) between left/right end-diastolic ventricular volumes obtained from short axis cine stacks vs. bT1RESS, and good-to-excellent correlation (0.84/0.64), p \u003C 0.001) for left/right end-diastolic atrial volumes. Discussion and conclusion: Free-breathing, whole-chest bT1RESS shows promise as a highly efficient and useful method for cardiovascular imaging. Diagnostic quality scans can be acquired regardless of post-contrast scan delay. Given the very short scan and reconstruction times, navigator-gated bT1RESS can be easily incorporated into any CMR protocol to allow volumetric evaluation of the thoracic vasculature and heart. With further development, the technique could also prove useful for rapid 3D functional evaluation of the heart.  \nList of Abbreviations: CMR, cardiovascular magnetic resonance; bSSFP, balanced steady-state free precession; bT1RESS, balanced T1 Relaxation-Enhanced SteadyState; 3D, three-dimensional; SIR, signal ","cbCaitkmQFiaB5dq","https://ap.wps.com/l/cbCaitkmQFiaB5dq","pdf",7763509,"English","# Abstract\n## Background and purpose\n## Methods\n## Results\n## Discussion and conclusion\n## List of abbreviations","[{\"question\":\"What problem does the equilibrium phase bT1RESS approach address in angiography?\",\"answer\":\"Post-contrast angiographic image quality declines rapidly after the first pass, limiting the usable scan window to tens of seconds. bT1RESS is designed to enable diagnostic CEMRA beyond this limited window.\"},{\"question\":\"How was the free-breathing whole-chest bT1RESS sequence evaluated in the study?\",\"answer\":\"IRB-approved imaging was performed on 34 patients using a standard CMR protocol plus a post-contrast prototype navigator-gated whole-chest bT1RESS sequence with GRAPPA acceleration (2×2 or 3×2 slice x phase).\"},{\"question\":\"What results were reported for scan time and image quality?\",\"answer\":\"Median scan time was shorter with 3×2 acceleration (1.25 min) than with 2×2 acceleration (2.21 min). Good-to-excellent visualization of major cardiovascular structures was reported in all cases with 3×2 acceleration and all but one with 2×2 acceleration, supporting overall diagnostic quality.\"}]","Highly efficient, free-breathing whole-chest equilibrium phase bT1RESS MR angiography - Initial clinical experience | PDF",1790748297,25]