[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-374078-105":59,"doc-detail-374078-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","habitual-sleep-duration-healthy-eating-and-digestive-system-cancer-mortality","Habitual sleep duration, healthy eating, and digestive system cancer mortality","","Lifestyle patterns including sleep duration and diet substantially affect digestive health and may shape mortality risk from digestive system cancer. This study evaluated associations between sleep duration categories and dietary habits in 406,584 UK Biobank participants (median follow-up 12.6 years). Results showed both short and long sleep correlated with higher digestive cancer mortality, while healthier dietary scores aligned with lower risk. After adjustment for smoking, type 2 diabetes, and BMI, sleep associations disappeared.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/habitual-sleep-duration-healthy-eating-and-digestive-system-cancer-mortality/374078/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/habitual-sleep-duration-healthy-eating-and-digestive-system-cancer-mortality/374078.png","ImageObject",300,407,{"name":92,"@type":93},"Olivia Brown","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-24","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"How were sleep duration groups defined in this study?","Question",{"text":112,"@type":113},"Sleep duration was classified as short (≤ 6 h), normal (7–8 h), and long (≥ 9 h) based on reported daily sleep.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What does the dietary “health score” represent?",{"text":117,"@type":113},"The score combined fibre intake (at least 25 g/day), fruit and vegetable portions (seven portions/day), and meat servings (fewer than four servings/week), yielding categories from least to healthiest.",{"name":119,"@type":110,"acceptedAnswer":120},"Why did the association between sleep duration and digestive cancer mortality change after adjustments?",{"text":121,"@type":113},"Adjusting for smoking, type 2 diabetes, and BMI status eliminated the association, suggesting those factors explained the observed sleep-related risk differences.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},374078,1790459301,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":41},16904993612988,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Nôga etal. BMC Medicine (2025) 23:44 [https://doi.org/10.1186/s12916-025-03882-w](https://doi.org/10.1186/s12916-025-03882-w)  \nBMC Medicine  \n RESEARCH Open Access  \nHabitual sleep duration, healthy eating, and digestive system cancer mortality  \nDiana A. Nôga 1*, Elisa M. S. Meth 1, André P. Pacheco 1,2,3, Jonathan Cedernaes4,5, Pei Xue1 and Christian Benedict 1  \nAbstract  \nBackground Lifestyle choices, such as dietary patterns and sleep duration, significantly impact the health  \nof the digestive system and may influence the risk of mortality from digestive system cancer.  \nMethods This study aimed to examine the associations between sleep duration, dietary habits, and mortality  \nfrom digestive system cancers. The analysis included 406,584 participants from the UK Biobank cohort (54 . 1% women; age range: 38–73 years), with sleep duration classified as short (≤ 6 h, 24 . 2%), normal (7–8 h, 68 .4%), and long (≥ 9 h, 7.4%) . Healthy eating habits were defined as a daily intake of at least 25 g of fibre, seven portions of fruits and vegetables, and fewer than four servings of meat per week. These dietary factors were combined into a score ranging from 0 (least healthy) to 3 (healthiest) . Cox proportional hazards regression analyses were conducted, with a median followup period of 12.6 years, ending on September 30, 2021.  \nResults 3949 participants died from cancer of the digestive system. Both short and long sleep duration were associated with an increased risk of mortality from cancer of the digestive system (1 .09 (1 .01–1. 18) and 1.14 (1 .03–1. 27), respectively) . Additionally, a diet score ≥ 1 was linked to a lower cancer risk (0 .72–0.91 (0 .59–0. 96)) . Adjusting for smoking, type 2 diabetes, and body mass index (BMI) status eliminated the association between sleep duration and digestive cancer mortality. The association between healthy dietary patterns and the risk of digestive system cancer mortality did not vary by sleep duration.  \nConclusions Aberrant sleep durations may increase the risk of mortality from digestive system cancer, potentially through smoking, higher BMI, and type 2 diabetes. However, aberrant sleep durations do not seem to reduce the protective effects of a healthy dietary pattern.  \nKeywords Lifestyle, Fibre, Fruits, Vegetables, Meat, UK Biobank Cohort, Risk analysis  \n*Correspondence:  \nDiana A. Nôga [diana.noga.morais@uu.se](diana.noga.morais@uu.se)  \n1 Department of Pharmaceutical Biosciences, Uppsala University, Box 593, Husargatan 3, Uppsala 751 24, Sweden  \n2 Department of Research and Innovation, Division of Mental Health and Addiction, Oslo University Hospital, Sognsvannsveien 21, Oslo 0372, Norway  \n3 Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Postboks 1039 Blindern, 0315, Oslo, Norway  \n4 Department of Medical Sciences, Uppsala University, Akademiska Sjukhuset, Ing. 40, 5 Tr, Uppsala 751 85, Sweden  \n5 Department of Medical Cell Biology, Uppsala University, Box 571, Husargatan 3, Uppsala 751 24, Sweden  \nBackground  \nCancer in the digestive system poses a significant public health burden worldwide, making successful prevention essential for reducing morbidity and mortality [1]. In this context, epidemiological evidence underscores the importance of daily sleep duration [2–6]. For instance, a study from the UK Biobank cohort found that individuals sleeping more than 9 h per day had a higher susceptibility to oesophageal adenocarcinoma compared with those sleeping 7 h [5]. Furthermore, research involving a US cohort identified associations between both short and long sleep durations and the incidence of hepatocellular  \n© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons li","cbCaieeo7s1uDwsp","https://ap.wps.com/l/cbCaieeo7s1uDwsp","pdf",1420680,12,"English","# Background\n## Lifestyle factors and digestive cancer\n# Methods\n## Study population and exposure definitions\n## Follow-up and statistical approach\n# Results\n## Mortality findings for sleep duration\n## Dietary score and risk\n## Adjustment effects\n# Conclusions\n## Interpretations and implications","[{\"question\":\"How were sleep duration groups defined in this study?\",\"answer\":\"Sleep duration was classified as short (≤ 6 h), normal (7–8 h), and long (≥ 9 h) based on reported daily sleep.\"},{\"question\":\"What does the dietary “health score” represent?\",\"answer\":\"The score combined fibre intake (at least 25 g/day), fruit and vegetable portions (seven portions/day), and meat servings (fewer than four servings/week), yielding categories from least to healthiest.\"},{\"question\":\"Why did the association between sleep duration and digestive cancer mortality change after adjustments?\",\"answer\":\"Adjusting for smoking, type 2 diabetes, and BMI status eliminated the association, suggesting those factors explained the observed sleep-related risk differences.\"}]","Habitual sleep duration, healthy eating, and digestive system cancer mortality | PDF",1790201103]