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Early cervical therapy may be delayed until fetal lung maturation and cesarean delivery is considered when disease predominates, while advanced disease often needs chemoradiotherapy, which conflicts with pregnancy preservation. For ovarian cancer, early-stage diagnosis is common; adnexal removal may support evaluation with staging possible post-delivery. Selected advanced cases may consider neoadjuvant chemotherapy after thorough multidisciplinary 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cancer?",{"text":72,"@type":64},"Chemoradiotherapy, recommended for advanced stages, is stated to be incompatible with pregnancy preservation.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},330384,1790200349,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,115,120,123,127],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & 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\nKatja Stenström Bohlin  | Mats Brännström  | Pernilla Dahm-Kähler  \nDepartment of Obstetrics and Gynecology, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden  \nCorrespondence  \nKatja Stenström Bohlin, Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden.  \nEmail: [katja.bohlin@vgregion.se](katja.bohlin@vgregion.se)  \nAbstract  \nGynecological cancer diagnosed during pregnancy requires accurate diagnosis and staging to determine optimal treatment based on gestational age. Cervical and ovarian cancers are the most common and multidisciplinary team collaboration is pivotal. Magnetic resonance imaging and ultrasound can be used without causing fetal harm. In cervical cancer, early-stage treatments can often be delayed until fetal lung maturation and cesarean section is recommended if disease prevails, in combination with a simple/radical hysterectomy and lymphadenectomy. Chemoradiotherapy, the recommended treatment for advanced stages, is not compatible with pregnancy preservation. Most gestational ovarian cancers are diagnosed at an early stage and consist of nonepithelial cancers or borderline tumors. Removal of the affected adnexa during pregnancy is often necessary for diagnosis, though staging can be performed after delivery. In selected cases of advanced cervical and ovarian cancers, neoadjuvant chemotherapy may be an option to allow gestational advancement but only after thorough multidisciplinary discussions and counseling.  \nK E Y WO R D S  \ncervical cancer, endometrial cancer, oncology, ovarian cancer, pregnancy, vulvar cancer  \nCancer during pregnancy is a rare condition, though healthcare is becoming more exposed to it due to the increasing risk of acquiring cancer during the fertile period over the past 20years.1 The incidence of cancer during pregnancy is estimated to be 1 in 1000 pregnancies, including cases within a year after delivery, the period when most cancers are identified. A small group of women is diagnosed during pregnancy, often with rapidly progressing disease. The outcome, for both the mother and child, is more favorable if diagnosed in the last trimester. The incidence numbers are assumed to be underreported, as registry-based studies have found that terminated pregnancies due to malignancies are seldom reported.2 Next to breast and hematological malignancies, gynecological cancers are the most frequent occurring  \nmalignancies during pregnancy although rare. Among gynecological cancers mainly cervical and ovarian cancer are found and fortunately often diagnosed in early stages of the disease. Endometrial and vulvar cancer are rarely seen.3 Nevertheless, these are complex medical conditions that requires careful management and considerations in each case. Importantly, the recommended treatment of gynecological cancer has in most cases an impact on fertility as it affects the reproductive organs. This is the greatest challenge when it occurs during pregnancy: Is fertility and pregnancy sparing treatment an option?  \nA correct and adequate diagnosis and staging are essential to determine when and how treatment should be initiated in relation  \nto the length of the pregnancy. Treatment should not be hastened  \n\n| Abbreviations: BOT, borderline tumor; MRI, magnetic resonance imaging. |\n| --- |\n| This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.\u003Cbr>© 2024 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetricsand Gynecology (NFOG) . |\n\nActa Obstet Gynecol Scand. 2024;103:761–[766.](766. wileyonlinelibrary.com/journal/aogs | 761)[ wi","cbCaieFT3d5wmX5X","https://ap.wps.com/l/cbCaieFT3d5wmX5X","pdf",494516,"English","# Abstract\n## Diagnosis and staging\n## Imaging and fetal safety\n## Cervical cancer management\n## Ovarian cancer management\n## Advanced disease and multidisciplinary decision-making","[{\"question\":\"Why is accurate diagnosis and staging crucial for gynecological cancer during pregnancy?\",\"answer\":\"Accurate diagnosis and staging determine when and how treatment should start relative to gestational age, enabling selection of the most suitable approach.\"},{\"question\":\"How can MRI and ultrasound be used in pregnant patients?\",\"answer\":\"MRI and ultrasound are described as options that can be used without causing fetal harm.\"},{\"question\":\"What treatment conflicts with preserving pregnancy in advanced cervical cancer?\",\"answer\":\"Chemoradiotherapy, recommended for advanced stages, is stated to be incompatible with pregnancy preservation.\"}]","Gynecological cancer during pregnancy - From a gyneoncological perspective | PDF",1789988573,15]